Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries

Detalhes bibliográficos
Autor(a) principal: Morúa,O. C.
Data de Publicação: 2021
Outros Autores: Cardoso,M. J. B., Silva,H. N. da, Carrodeguas,R. G., Rodríguez,M. A., Fook,M. V. L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cerâmica (São Paulo. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132021000300289
Resumo: Abstract The objective of this work was to produce brushite cement for orthopedic applications, based on the system wollastonite/phosphoric acid with the incorporation of polyethylene glycol (PEG) as a setting and processing additive. Brushite/PEG cement was obtained by the dissolution-precipitation method and its physicochemical properties were characterized by X-ray diffraction, compressive strength, porosimetry, and biological behavior (cell adhesion and bioactivity tests). The results indicated the formation of brushite cement with 21.4 MPa of compressive strength and 30% porosity, similar to human trabecular bone. The surface was shown to be adequate for cell adhesion and growth and bioactive with the formation of apatite layers. The incorporation of PEG improved working conditions without causing undesirable changes in the physicochemical properties and biological behavior of developed cement, thus promising for the repair of bone tissue injuries.
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network_name_str Cerâmica (São Paulo. Online)
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spelling Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuriesbrushitewollastonitePEGbone cementsbiomaterialsAbstract The objective of this work was to produce brushite cement for orthopedic applications, based on the system wollastonite/phosphoric acid with the incorporation of polyethylene glycol (PEG) as a setting and processing additive. Brushite/PEG cement was obtained by the dissolution-precipitation method and its physicochemical properties were characterized by X-ray diffraction, compressive strength, porosimetry, and biological behavior (cell adhesion and bioactivity tests). The results indicated the formation of brushite cement with 21.4 MPa of compressive strength and 30% porosity, similar to human trabecular bone. The surface was shown to be adequate for cell adhesion and growth and bioactive with the formation of apatite layers. The incorporation of PEG improved working conditions without causing undesirable changes in the physicochemical properties and biological behavior of developed cement, thus promising for the repair of bone tissue injuries.Associação Brasileira de Cerâmica2021-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132021000300289Cerâmica v.67 n.383 2021reponame:Cerâmica (São Paulo. Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/0366-69132021673833054info:eu-repo/semantics/openAccessMorúa,O. C.Cardoso,M. J. B.Silva,H. N. daCarrodeguas,R. G.Rodríguez,M. A.Fook,M. V. L.eng2021-09-24T00:00:00Zoai:scielo:S0366-69132021000300289Revistahttps://www.scielo.br/j/ce/PUBhttps://old.scielo.br/oai/scielo-oai.phpceram.abc@gmail.com||ceram.abc@gmail.com1678-45530366-6913opendoar:2021-09-24T00:00Cerâmica (São Paulo. Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries
title Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries
spellingShingle Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries
Morúa,O. C.
brushite
wollastonite
PEG
bone cements
biomaterials
title_short Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries
title_full Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries
title_fullStr Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries
title_full_unstemmed Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries
title_sort Synthesis of brushite/polyethylene glycol cement for filler in bone tissue injuries
author Morúa,O. C.
author_facet Morúa,O. C.
Cardoso,M. J. B.
Silva,H. N. da
Carrodeguas,R. G.
Rodríguez,M. A.
Fook,M. V. L.
author_role author
author2 Cardoso,M. J. B.
Silva,H. N. da
Carrodeguas,R. G.
Rodríguez,M. A.
Fook,M. V. L.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Morúa,O. C.
Cardoso,M. J. B.
Silva,H. N. da
Carrodeguas,R. G.
Rodríguez,M. A.
Fook,M. V. L.
dc.subject.por.fl_str_mv brushite
wollastonite
PEG
bone cements
biomaterials
topic brushite
wollastonite
PEG
bone cements
biomaterials
description Abstract The objective of this work was to produce brushite cement for orthopedic applications, based on the system wollastonite/phosphoric acid with the incorporation of polyethylene glycol (PEG) as a setting and processing additive. Brushite/PEG cement was obtained by the dissolution-precipitation method and its physicochemical properties were characterized by X-ray diffraction, compressive strength, porosimetry, and biological behavior (cell adhesion and bioactivity tests). The results indicated the formation of brushite cement with 21.4 MPa of compressive strength and 30% porosity, similar to human trabecular bone. The surface was shown to be adequate for cell adhesion and growth and bioactive with the formation of apatite layers. The incorporation of PEG improved working conditions without causing undesirable changes in the physicochemical properties and biological behavior of developed cement, thus promising for the repair of bone tissue injuries.
publishDate 2021
dc.date.none.fl_str_mv 2021-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132021000300289
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132021000300289
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0366-69132021673833054
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Cerâmica
publisher.none.fl_str_mv Associação Brasileira de Cerâmica
dc.source.none.fl_str_mv Cerâmica v.67 n.383 2021
reponame:Cerâmica (São Paulo. Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Cerâmica (São Paulo. Online)
collection Cerâmica (São Paulo. Online)
repository.name.fl_str_mv Cerâmica (São Paulo. Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ceram.abc@gmail.com||ceram.abc@gmail.com
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