Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity

Detalhes bibliográficos
Autor(a) principal: Govindan, Ramu
Data de Publicação: 2023
Outros Autores: Anh Huy, Roan Ngoc, Sivaramakumar, Navanita, Raman, Rajesh, Jayaraman, Saravanan, Basavan, Duraiswamy, Palanisamy, Dhanabal S
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Pharmaceutical Sciences
Texto Completo: https://www.revistas.usp.br/bjps/article/view/208316
Resumo: The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.
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spelling Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activityCalculiLitholyticBasella rubra Plant organsThe inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.Universidade de São Paulo. Faculdade de Ciências Farmacêuticas2023-02-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjps/article/view/20831610.1590/s2175-97902022e20582Brazilian Journal of Pharmaceutical Sciences; Vol. 58 (2022)Brazilian Journal of Pharmaceutical Sciences; v. 58 (2022)Brazilian Journal of Pharmaceutical Sciences; Vol. 58 (2022)2175-97901984-8250reponame:Brazilian Journal of Pharmaceutical Sciencesinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/bjps/article/view/208316/197671Copyright (c) 2022 Brazilian Journal of Pharmaceutical Scienceshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGovindan, RamuAnh Huy, Roan Ngoc Sivaramakumar, Navanita Raman, RajeshJayaraman, SaravananBasavan, Duraiswamy Palanisamy, Dhanabal S 2023-08-30T19:40:51Zoai:revistas.usp.br:article/208316Revistahttps://www.revistas.usp.br/bjps/indexPUBhttps://old.scielo.br/oai/scielo-oai.phpbjps@usp.br||elizabeth.igne@gmail.com2175-97901984-8250opendoar:2023-08-30T19:40:51Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
title Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
spellingShingle Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
Govindan, Ramu
Calculi
Litholytic
Basella rubra
Plant organs
title_short Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
title_full Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
title_fullStr Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
title_full_unstemmed Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
title_sort Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
author Govindan, Ramu
author_facet Govindan, Ramu
Anh Huy, Roan Ngoc
Sivaramakumar, Navanita
Raman, Rajesh
Jayaraman, Saravanan
Basavan, Duraiswamy
Palanisamy, Dhanabal S
author_role author
author2 Anh Huy, Roan Ngoc
Sivaramakumar, Navanita
Raman, Rajesh
Jayaraman, Saravanan
Basavan, Duraiswamy
Palanisamy, Dhanabal S
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Govindan, Ramu
Anh Huy, Roan Ngoc
Sivaramakumar, Navanita
Raman, Rajesh
Jayaraman, Saravanan
Basavan, Duraiswamy
Palanisamy, Dhanabal S
dc.subject.por.fl_str_mv Calculi
Litholytic
Basella rubra
Plant organs
topic Calculi
Litholytic
Basella rubra
Plant organs
description The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.
publishDate 2023
dc.date.none.fl_str_mv 2023-02-17
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjps/article/view/208316
10.1590/s2175-97902022e20582
url https://www.revistas.usp.br/bjps/article/view/208316
identifier_str_mv 10.1590/s2175-97902022e20582
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjps/article/view/208316/197671
dc.rights.driver.fl_str_mv Copyright (c) 2022 Brazilian Journal of Pharmaceutical Sciences
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Brazilian Journal of Pharmaceutical Sciences
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Ciências Farmacêuticas
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Ciências Farmacêuticas
dc.source.none.fl_str_mv Brazilian Journal of Pharmaceutical Sciences; Vol. 58 (2022)
Brazilian Journal of Pharmaceutical Sciences; v. 58 (2022)
Brazilian Journal of Pharmaceutical Sciences; Vol. 58 (2022)
2175-9790
1984-8250
reponame:Brazilian Journal of Pharmaceutical Sciences
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Pharmaceutical Sciences
collection Brazilian Journal of Pharmaceutical Sciences
repository.name.fl_str_mv Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP)
repository.mail.fl_str_mv bjps@usp.br||elizabeth.igne@gmail.com
_version_ 1800222917603098624

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