Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Pharmaceutical Sciences |
Texto Completo: | https://www.revistas.usp.br/bjps/article/view/207608 |
Resumo: | Resistant starch is particularly concerned with beneficial effects in regulating blood glucose concentration and lipid metabolism, reducing the risk of diabetes and cardiovascular diseases. This study aimed to validate the effects of wheat starch acetate containing 32.1% resistant starch on postprandial blood glucose response and lipid profile on obesity, dyslipidemia Swiss mice induced by a high-fat diet. The result showed that there was a restriction on postprandial hyperglycemia and remained stable for 2 hours after meal efficiently comparing with the control group fed natural wheat starch. Simultaneously, when maintaining the dose of 5g/kg once or twice a day for 8 weeks, wheat starch acetate to be able to reduce body weight and blood glucose, triglyceride, cholesterol levels compared to the control group (p<0.05). |
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USP-31 |
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Brazilian Journal of Pharmaceutical Sciences |
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Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia miceAcetate wheat starchGlucoseLipidCholesterolResistant starch is particularly concerned with beneficial effects in regulating blood glucose concentration and lipid metabolism, reducing the risk of diabetes and cardiovascular diseases. This study aimed to validate the effects of wheat starch acetate containing 32.1% resistant starch on postprandial blood glucose response and lipid profile on obesity, dyslipidemia Swiss mice induced by a high-fat diet. The result showed that there was a restriction on postprandial hyperglycemia and remained stable for 2 hours after meal efficiently comparing with the control group fed natural wheat starch. Simultaneously, when maintaining the dose of 5g/kg once or twice a day for 8 weeks, wheat starch acetate to be able to reduce body weight and blood glucose, triglyceride, cholesterol levels compared to the control group (p<0.05).Universidade de São Paulo. Faculdade de Ciências Farmacêuticas2023-02-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjps/article/view/20760810.1590/s2175-97902022e20890Brazilian Journal of Pharmaceutical Sciences; Vol. 58 (2022)Brazilian Journal of Pharmaceutical Sciences; v. 58 (2022)Brazilian Journal of Pharmaceutical Sciences; Vol. 58 (2022)2175-97901984-8250reponame:Brazilian Journal of Pharmaceutical Sciencesinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/bjps/article/view/207608/197666Copyright (c) 2022 Brazilian Journal of Pharmaceutical Scienceshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessChu Thi Thu HienPhu Thi HoaNguyen Hai ThuyTran Huu Dung2023-08-30T19:27:37Zoai:revistas.usp.br:article/207608Revistahttps://www.revistas.usp.br/bjps/indexPUBhttps://old.scielo.br/oai/scielo-oai.phpbjps@usp.br||elizabeth.igne@gmail.com2175-97901984-8250opendoar:2023-08-30T19:27:37Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice |
title |
Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice |
spellingShingle |
Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice Chu Thi Thu Hien Acetate wheat starch Glucose Lipid Cholesterol |
title_short |
Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice |
title_full |
Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice |
title_fullStr |
Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice |
title_full_unstemmed |
Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice |
title_sort |
Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice |
author |
Chu Thi Thu Hien |
author_facet |
Chu Thi Thu Hien Phu Thi Hoa Nguyen Hai Thuy Tran Huu Dung |
author_role |
author |
author2 |
Phu Thi Hoa Nguyen Hai Thuy Tran Huu Dung |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Chu Thi Thu Hien Phu Thi Hoa Nguyen Hai Thuy Tran Huu Dung |
dc.subject.por.fl_str_mv |
Acetate wheat starch Glucose Lipid Cholesterol |
topic |
Acetate wheat starch Glucose Lipid Cholesterol |
description |
Resistant starch is particularly concerned with beneficial effects in regulating blood glucose concentration and lipid metabolism, reducing the risk of diabetes and cardiovascular diseases. This study aimed to validate the effects of wheat starch acetate containing 32.1% resistant starch on postprandial blood glucose response and lipid profile on obesity, dyslipidemia Swiss mice induced by a high-fat diet. The result showed that there was a restriction on postprandial hyperglycemia and remained stable for 2 hours after meal efficiently comparing with the control group fed natural wheat starch. Simultaneously, when maintaining the dose of 5g/kg once or twice a day for 8 weeks, wheat starch acetate to be able to reduce body weight and blood glucose, triglyceride, cholesterol levels compared to the control group (p<0.05). |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-02-02 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/bjps/article/view/207608 10.1590/s2175-97902022e20890 |
url |
https://www.revistas.usp.br/bjps/article/view/207608 |
identifier_str_mv |
10.1590/s2175-97902022e20890 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/bjps/article/view/207608/197666 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Brazilian Journal of Pharmaceutical Sciences https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Brazilian Journal of Pharmaceutical Sciences https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Ciências Farmacêuticas |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Ciências Farmacêuticas |
dc.source.none.fl_str_mv |
Brazilian Journal of Pharmaceutical Sciences; Vol. 58 (2022) Brazilian Journal of Pharmaceutical Sciences; v. 58 (2022) Brazilian Journal of Pharmaceutical Sciences; Vol. 58 (2022) 2175-9790 1984-8250 reponame:Brazilian Journal of Pharmaceutical Sciences instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Brazilian Journal of Pharmaceutical Sciences |
collection |
Brazilian Journal of Pharmaceutical Sciences |
repository.name.fl_str_mv |
Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
bjps@usp.br||elizabeth.igne@gmail.com |
_version_ |
1800222917136482304 |