The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Pharmaceutical Sciences |
Texto Completo: | https://www.revistas.usp.br/bjps/article/view/159305 |
Resumo: | The objective of the study was to evaluate the use of human albumin in a Brazilian university hospital, in compliance with the institutional protocol and other clinical guidelines, taking into account the therapeutic indications and the dosage regimens. Data was obtained from the pharmacy dispensing records of human albumin, the requests for use it and, when available, the patient’s records between January and October 2017. After evaluation the therapeutic indications and the dosage regimens were classified as “appropriate” and “inappropriate”. The analysis of 98 requests showed that, when compared to the institutional protocol, 54 (55.1%) requests had an inappropriate therapeutic indication. However, when a comparison was made between 25 medical records (54 requests) and other clinical guidelines, it was observed that the therapeutic indication had none classified as inappropriate. In addition, 16 (29.7%) requests were considered inappropriate in relation to dosage regimens. From these results, it was possible to conclude that although the use of human albumin in the hospital was associated to a clinical protocol, it was outdated. Thus, it is possible to affirm that not only the adoption of a clinical protocol, but its periodical updating is an important strategy to promote the rational use of drugs. |
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Brazilian Journal of Pharmaceutical Sciences |
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The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimenAlbumins/drug utilization reviewHealth servicesUniversity Hospital/BrazilDrugs/useThe objective of the study was to evaluate the use of human albumin in a Brazilian university hospital, in compliance with the institutional protocol and other clinical guidelines, taking into account the therapeutic indications and the dosage regimens. Data was obtained from the pharmacy dispensing records of human albumin, the requests for use it and, when available, the patient’s records between January and October 2017. After evaluation the therapeutic indications and the dosage regimens were classified as “appropriate” and “inappropriate”. The analysis of 98 requests showed that, when compared to the institutional protocol, 54 (55.1%) requests had an inappropriate therapeutic indication. However, when a comparison was made between 25 medical records (54 requests) and other clinical guidelines, it was observed that the therapeutic indication had none classified as inappropriate. In addition, 16 (29.7%) requests were considered inappropriate in relation to dosage regimens. From these results, it was possible to conclude that although the use of human albumin in the hospital was associated to a clinical protocol, it was outdated. Thus, it is possible to affirm that not only the adoption of a clinical protocol, but its periodical updating is an important strategy to promote the rational use of drugs.Universidade de São Paulo. Faculdade de Ciências Farmacêuticas2018-12-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjps/article/view/15930510.1590/s2175-97902018000418008Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. 4 (2018); e18008Brazilian Journal of Pharmaceutical Sciences; v. 54 n. 4 (2018); e18008Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. 4 (2018); e180082175-97901984-8250reponame:Brazilian Journal of Pharmaceutical Sciencesinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/bjps/article/view/159305/154101Copyright (c) 2018 Brazilian Journal of Pharmaceutical Sciencesinfo:eu-repo/semantics/openAccessIshida, Tatiane SayuriSakai, Maria CristinaMelo, Daniela Oliveira de2019-06-24T20:15:38Zoai:revistas.usp.br:article/159305Revistahttps://www.revistas.usp.br/bjps/indexPUBhttps://old.scielo.br/oai/scielo-oai.phpbjps@usp.br||elizabeth.igne@gmail.com2175-97901984-8250opendoar:2019-06-24T20:15:38Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen |
title |
The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen |
spellingShingle |
The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen Ishida, Tatiane Sayuri Albumins/drug utilization review Health services University Hospital/Brazil Drugs/use |
title_short |
The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen |
title_full |
The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen |
title_fullStr |
The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen |
title_full_unstemmed |
The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen |
title_sort |
The appropriate use of human albumin in a Brazilian University Hospital: therapeutic indication and dosage regimen |
author |
Ishida, Tatiane Sayuri |
author_facet |
Ishida, Tatiane Sayuri Sakai, Maria Cristina Melo, Daniela Oliveira de |
author_role |
author |
author2 |
Sakai, Maria Cristina Melo, Daniela Oliveira de |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Ishida, Tatiane Sayuri Sakai, Maria Cristina Melo, Daniela Oliveira de |
dc.subject.por.fl_str_mv |
Albumins/drug utilization review Health services University Hospital/Brazil Drugs/use |
topic |
Albumins/drug utilization review Health services University Hospital/Brazil Drugs/use |
description |
The objective of the study was to evaluate the use of human albumin in a Brazilian university hospital, in compliance with the institutional protocol and other clinical guidelines, taking into account the therapeutic indications and the dosage regimens. Data was obtained from the pharmacy dispensing records of human albumin, the requests for use it and, when available, the patient’s records between January and October 2017. After evaluation the therapeutic indications and the dosage regimens were classified as “appropriate” and “inappropriate”. The analysis of 98 requests showed that, when compared to the institutional protocol, 54 (55.1%) requests had an inappropriate therapeutic indication. However, when a comparison was made between 25 medical records (54 requests) and other clinical guidelines, it was observed that the therapeutic indication had none classified as inappropriate. In addition, 16 (29.7%) requests were considered inappropriate in relation to dosage regimens. From these results, it was possible to conclude that although the use of human albumin in the hospital was associated to a clinical protocol, it was outdated. Thus, it is possible to affirm that not only the adoption of a clinical protocol, but its periodical updating is an important strategy to promote the rational use of drugs. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-20 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/bjps/article/view/159305 10.1590/s2175-97902018000418008 |
url |
https://www.revistas.usp.br/bjps/article/view/159305 |
identifier_str_mv |
10.1590/s2175-97902018000418008 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/bjps/article/view/159305/154101 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Brazilian Journal of Pharmaceutical Sciences info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Brazilian Journal of Pharmaceutical Sciences |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Ciências Farmacêuticas |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Ciências Farmacêuticas |
dc.source.none.fl_str_mv |
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. 4 (2018); e18008 Brazilian Journal of Pharmaceutical Sciences; v. 54 n. 4 (2018); e18008 Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. 4 (2018); e18008 2175-9790 1984-8250 reponame:Brazilian Journal of Pharmaceutical Sciences instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Brazilian Journal of Pharmaceutical Sciences |
collection |
Brazilian Journal of Pharmaceutical Sciences |
repository.name.fl_str_mv |
Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
bjps@usp.br||elizabeth.igne@gmail.com |
_version_ |
1800222914409136128 |