Piroxicam voltammetric determination by ultra low cost pencil graphite electrode

Detalhes bibliográficos
Autor(a) principal: Macêdo, Isaac Yves Lopes de
Data de Publicação: 2020
Outros Autores: Alecrim, Morgana Fernandes, Oliveira Neto, Jerônimo Raimundo, Torres, Ieda Maria Sapateiro, Thomaz, Douglas Vieira, Gil, Eric de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Pharmaceutical Sciences
DOI: 10.1590/s2175-97902019000317344
Texto Completo: https://www.revistas.usp.br/bjps/article/view/181232
Resumo: Piroxicam (PRX) was determined in pharmaceutical capsules with differential pulse voltammetry (DPV) in a three electrode system consisting of a pencil graphite electrode (PGE) as working electrode, a Pt wire and a reference electrode of Ag/AgCl/KCl 3 M. An irreversible oxidation peak was observed in Epa c.a. 0.6 V, which correlates to the oxidation of PRX. The coefficient of linear correlation obtained was 0.9946, with limit of detection of 2.1 µM and limit of quantification of 4.7 µM. PGE assays showed good analytical performance compared to high performance liquid chromatography and spectrophotometry, showing the potential to be further developed and employed in quick and simple analyses.
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spelling Piroxicam voltammetric determination by ultra low cost pencil graphite electrodeElectroanalysisPencil graphite electrodePiroxicamVoltammetryPiroxicam (PRX) was determined in pharmaceutical capsules with differential pulse voltammetry (DPV) in a three electrode system consisting of a pencil graphite electrode (PGE) as working electrode, a Pt wire and a reference electrode of Ag/AgCl/KCl 3 M. An irreversible oxidation peak was observed in Epa c.a. 0.6 V, which correlates to the oxidation of PRX. The coefficient of linear correlation obtained was 0.9946, with limit of detection of 2.1 µM and limit of quantification of 4.7 µM. PGE assays showed good analytical performance compared to high performance liquid chromatography and spectrophotometry, showing the potential to be further developed and employed in quick and simple analyses.Universidade de São Paulo. Faculdade de Ciências Farmacêuticas2020-12-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjps/article/view/18123210.1590/s2175-97902019000317344Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e17344 Brazilian Journal of Pharmaceutical Sciences; v. 56 (2020); e17344 Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e17344 2175-97901984-8250reponame:Brazilian Journal of Pharmaceutical Sciencesinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/bjps/article/view/181232/168165Copyright (c) 2020 Brazilian Journal of Pharmaceutical Scienceshttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMacêdo, Isaac Yves Lopes de Alecrim, Morgana Fernandes Oliveira Neto, Jerônimo Raimundo Torres, Ieda Maria Sapateiro Thomaz, Douglas Vieira Gil, Eric de Souza 2021-06-12T19:46:54Zoai:revistas.usp.br:article/181232Revistahttps://www.revistas.usp.br/bjps/indexPUBhttps://old.scielo.br/oai/scielo-oai.phpbjps@usp.br||elizabeth.igne@gmail.com2175-97901984-8250opendoar:2021-06-12T19:46:54Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
title Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
spellingShingle Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
Macêdo, Isaac Yves Lopes de
Electroanalysis
Pencil graphite electrode
Piroxicam
Voltammetry
Macêdo, Isaac Yves Lopes de
Electroanalysis
Pencil graphite electrode
Piroxicam
Voltammetry
title_short Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
title_full Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
title_fullStr Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
title_full_unstemmed Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
title_sort Piroxicam voltammetric determination by ultra low cost pencil graphite electrode
author Macêdo, Isaac Yves Lopes de
author_facet Macêdo, Isaac Yves Lopes de
Macêdo, Isaac Yves Lopes de
Alecrim, Morgana Fernandes
Oliveira Neto, Jerônimo Raimundo
Torres, Ieda Maria Sapateiro
Thomaz, Douglas Vieira
Gil, Eric de Souza
Alecrim, Morgana Fernandes
Oliveira Neto, Jerônimo Raimundo
Torres, Ieda Maria Sapateiro
Thomaz, Douglas Vieira
Gil, Eric de Souza
author_role author
author2 Alecrim, Morgana Fernandes
Oliveira Neto, Jerônimo Raimundo
Torres, Ieda Maria Sapateiro
Thomaz, Douglas Vieira
Gil, Eric de Souza
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Macêdo, Isaac Yves Lopes de
Alecrim, Morgana Fernandes
Oliveira Neto, Jerônimo Raimundo
Torres, Ieda Maria Sapateiro
Thomaz, Douglas Vieira
Gil, Eric de Souza
dc.subject.por.fl_str_mv Electroanalysis
Pencil graphite electrode
Piroxicam
Voltammetry
topic Electroanalysis
Pencil graphite electrode
Piroxicam
Voltammetry
description Piroxicam (PRX) was determined in pharmaceutical capsules with differential pulse voltammetry (DPV) in a three electrode system consisting of a pencil graphite electrode (PGE) as working electrode, a Pt wire and a reference electrode of Ag/AgCl/KCl 3 M. An irreversible oxidation peak was observed in Epa c.a. 0.6 V, which correlates to the oxidation of PRX. The coefficient of linear correlation obtained was 0.9946, with limit of detection of 2.1 µM and limit of quantification of 4.7 µM. PGE assays showed good analytical performance compared to high performance liquid chromatography and spectrophotometry, showing the potential to be further developed and employed in quick and simple analyses.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-09
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjps/article/view/181232
10.1590/s2175-97902019000317344
url https://www.revistas.usp.br/bjps/article/view/181232
identifier_str_mv 10.1590/s2175-97902019000317344
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjps/article/view/181232/168165
dc.rights.driver.fl_str_mv Copyright (c) 2020 Brazilian Journal of Pharmaceutical Sciences
http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Brazilian Journal of Pharmaceutical Sciences
http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Ciências Farmacêuticas
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Ciências Farmacêuticas
dc.source.none.fl_str_mv Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e17344
Brazilian Journal of Pharmaceutical Sciences; v. 56 (2020); e17344
Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e17344
2175-9790
1984-8250
reponame:Brazilian Journal of Pharmaceutical Sciences
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Pharmaceutical Sciences
collection Brazilian Journal of Pharmaceutical Sciences
repository.name.fl_str_mv Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP)
repository.mail.fl_str_mv bjps@usp.br||elizabeth.igne@gmail.com
_version_ 1822181823106514944
dc.identifier.doi.none.fl_str_mv 10.1590/s2175-97902019000317344

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