Manifestação oral de mieloma múltiplo: um estudo de caso

Detalhes bibliográficos
Autor(a) principal: Tenório, Jefferson da Rocha
Data de Publicação: 2021
Outros Autores: Milani, Basílio de Almeida, Matuck, Bruno Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinical and Laboratorial Research in Dentistry
Texto Completo: https://www.revistas.usp.br/clrd/article/view/180062
Resumo: Multiple myeloma (MM) is a relatively uncommon oncohematological condition characterized by abnormal proliferation of plasma cells. Oral manifestations of MM can occur in soft and intraosseous parts. We present a case of a 69-year-old man diagnosed with MM and undergoing chemotherapy, referred to the dental service complaining of a nodular swelling in the maxilla. An incisional biopsy was conducted and the histopathological analysis showed a monoclonal proliferation of plasma cells with a positive CD 138 immunophenotype, which allowed the diagnosis of extramedullary plasmacytoma. The outcome of the case was unfavorable and the patient died. We emphasize the importance of diagnosing MM extramedullary disease in the maxillofacial region.
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spelling Manifestação oral de mieloma múltiplo: um estudo de casoOral manifestation of multiple myeloma: a case reportOral DiagnosisMultiple MyelomaOral CancerDiagnóstico bucalMieloma múltiploNeoplasias bucaisMultiple myeloma (MM) is a relatively uncommon oncohematological condition characterized by abnormal proliferation of plasma cells. Oral manifestations of MM can occur in soft and intraosseous parts. We present a case of a 69-year-old man diagnosed with MM and undergoing chemotherapy, referred to the dental service complaining of a nodular swelling in the maxilla. An incisional biopsy was conducted and the histopathological analysis showed a monoclonal proliferation of plasma cells with a positive CD 138 immunophenotype, which allowed the diagnosis of extramedullary plasmacytoma. The outcome of the case was unfavorable and the patient died. We emphasize the importance of diagnosing MM extramedullary disease in the maxillofacial region.O Mieloma múltiplo (MM) é uma condição oncohematológica relativamente incomum caracterizada pela proliferação anormal de células plasmáticas. Manifestações orais de MM podem ocorrer tanto em partes moles quanto intraósseas. Apresentamos o caso de um homem de 69 anos, diagnosticado com MM e em tratamento quimioterápico, levado a tratamento odontológico por uma queixa de inchaço nodular no maxilar. Uma biópsia incisional foi realizada e a análise histopatológica revelou uma proliferação monoclonal de células plasmáticas com imunofenótipo CD 138, levando ao diagnóstico de plasmocitoma extramedular. O desfecho do caso foi desfavorável, com o paciente indo a óbito. Enfatizamos a importância do diagnóstico de MM extramedular na região maxilofacial.Universidade de São Paulo. Faculdade de Odontologia2021-11-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clrd/article/view/180062Clinical and Laboratorial Research in Dentistry; 2021Clinical and Laboratorial Research in Dentistry; 20212357-8041reponame:Clinical and Laboratorial Research in Dentistryinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clrd/article/view/180062/177287Copyright (c) 2021 Jefferson da Rocha Tenório, Basílio de Almeida Milani, Bruno Fernandes Matuckhttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessTenório, Jefferson da RochaMilani, Basílio de AlmeidaMatuck, Bruno FernandesTenório, Jefferson da RochaMilani, Basílio de AlmeidaMatuck, Bruno Fernandes2022-02-18T14:02:47Zoai:revistas.usp.br:article/180062Revistahttps://www.revistas.usp.br/clrdPUBhttps://www.revistas.usp.br/clrd/oai||clrd.fo@usp.br2357-80412357-8041opendoar:2022-02-18T14:02:47Clinical and Laboratorial Research in Dentistry - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Manifestação oral de mieloma múltiplo: um estudo de caso
Oral manifestation of multiple myeloma: a case report
title Manifestação oral de mieloma múltiplo: um estudo de caso
spellingShingle Manifestação oral de mieloma múltiplo: um estudo de caso
Tenório, Jefferson da Rocha
Oral Diagnosis
Multiple Myeloma
Oral Cancer
Diagnóstico bucal
Mieloma múltiplo
Neoplasias bucais
title_short Manifestação oral de mieloma múltiplo: um estudo de caso
title_full Manifestação oral de mieloma múltiplo: um estudo de caso
title_fullStr Manifestação oral de mieloma múltiplo: um estudo de caso
title_full_unstemmed Manifestação oral de mieloma múltiplo: um estudo de caso
title_sort Manifestação oral de mieloma múltiplo: um estudo de caso
author Tenório, Jefferson da Rocha
author_facet Tenório, Jefferson da Rocha
Milani, Basílio de Almeida
Matuck, Bruno Fernandes
author_role author
author2 Milani, Basílio de Almeida
Matuck, Bruno Fernandes
author2_role author
author
dc.contributor.author.fl_str_mv Tenório, Jefferson da Rocha
Milani, Basílio de Almeida
Matuck, Bruno Fernandes
Tenório, Jefferson da Rocha
Milani, Basílio de Almeida
Matuck, Bruno Fernandes
dc.subject.por.fl_str_mv Oral Diagnosis
Multiple Myeloma
Oral Cancer
Diagnóstico bucal
Mieloma múltiplo
Neoplasias bucais
topic Oral Diagnosis
Multiple Myeloma
Oral Cancer
Diagnóstico bucal
Mieloma múltiplo
Neoplasias bucais
description Multiple myeloma (MM) is a relatively uncommon oncohematological condition characterized by abnormal proliferation of plasma cells. Oral manifestations of MM can occur in soft and intraosseous parts. We present a case of a 69-year-old man diagnosed with MM and undergoing chemotherapy, referred to the dental service complaining of a nodular swelling in the maxilla. An incisional biopsy was conducted and the histopathological analysis showed a monoclonal proliferation of plasma cells with a positive CD 138 immunophenotype, which allowed the diagnosis of extramedullary plasmacytoma. The outcome of the case was unfavorable and the patient died. We emphasize the importance of diagnosing MM extramedullary disease in the maxillofacial region.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-10
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clrd/article/view/180062
url https://www.revistas.usp.br/clrd/article/view/180062
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clrd/article/view/180062/177287
dc.rights.driver.fl_str_mv Copyright (c) 2021 Jefferson da Rocha Tenório, Basílio de Almeida Milani, Bruno Fernandes Matuck
http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Jefferson da Rocha Tenório, Basílio de Almeida Milani, Bruno Fernandes Matuck
http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia
dc.source.none.fl_str_mv Clinical and Laboratorial Research in Dentistry; 2021
Clinical and Laboratorial Research in Dentistry; 2021
2357-8041
reponame:Clinical and Laboratorial Research in Dentistry
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinical and Laboratorial Research in Dentistry
collection Clinical and Laboratorial Research in Dentistry
repository.name.fl_str_mv Clinical and Laboratorial Research in Dentistry - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clrd.fo@usp.br
_version_ 1800222878225924096

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