Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)

Detalhes bibliográficos
Autor(a) principal: Brunckhorst, Claudia Stoll
Data de Publicação: 2000
Outros Autores: Vuono, Laudinor de, Barnabe, Renato Camparanut
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
Texto Completo: https://www.revistas.usp.br/bjvras/article/view/5819
Resumo: The problem of the choice of a reliable and safe method of elective interruption of pregnancy in bitches was analysed. The methods are common in the small animal practice in preventing the birth of unwanted litters and are considered an important factor not only for the solution of owners personal problems, but also for this species population control. The favorable aspects and the counter indications of surgical and medicamental interruption of pregnancy were discussed. The surgical interruption is considered as the best choice for animals not intended to be utilized for reproduction. The serious side effects restricted the use of estrogens, tamoxifen citrate and non- hormonal embryotoxic agents. Epostane needs more studies to confirm its efficiency. Although possible, the utilization of analogues of GnRH still has supplying and cost limitations. The specificity of the used agents and their possible side effects limit immunological control of pregnancy. The use of glucocorticoids is limited through the length of the treatment and side effects. Mifepristone and aglepristone, commercially unavailable products, have been indicated as promising drugs in the future due to their efficiency, security and utilization during all stages of pregnancy. Despite the previsible side effects and the necessity of hospitalization for the treated animals, prostaglandins are more and more utilized as abortive drugs. Throughout dopamine agonists, cabergoline presents the best results, especially when associated with the analog of the prostaglandin cloprostenol. It can be used as soon as the diagnosis of pregnancy is possible, with 100% of efficiency and little side effects.
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spelling Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)Interrupção eletiva da gestação em cães (Canis familiaris, Linnaeus, 1758)PrenhezAbortoCadelasPregnancyAbortionBitchesThe problem of the choice of a reliable and safe method of elective interruption of pregnancy in bitches was analysed. The methods are common in the small animal practice in preventing the birth of unwanted litters and are considered an important factor not only for the solution of owners personal problems, but also for this species population control. The favorable aspects and the counter indications of surgical and medicamental interruption of pregnancy were discussed. The surgical interruption is considered as the best choice for animals not intended to be utilized for reproduction. The serious side effects restricted the use of estrogens, tamoxifen citrate and non- hormonal embryotoxic agents. Epostane needs more studies to confirm its efficiency. Although possible, the utilization of analogues of GnRH still has supplying and cost limitations. The specificity of the used agents and their possible side effects limit immunological control of pregnancy. The use of glucocorticoids is limited through the length of the treatment and side effects. Mifepristone and aglepristone, commercially unavailable products, have been indicated as promising drugs in the future due to their efficiency, security and utilization during all stages of pregnancy. Despite the previsible side effects and the necessity of hospitalization for the treated animals, prostaglandins are more and more utilized as abortive drugs. Throughout dopamine agonists, cabergoline presents the best results, especially when associated with the analog of the prostaglandin cloprostenol. It can be used as soon as the diagnosis of pregnancy is possible, with 100% of efficiency and little side effects.Analisou-se a problemática da escolha de um método confiável e seguro para a interrupção eletiva da gestação em cadelas, prática comum em clínica de pequenos animais para a prevenção do nascimento de ninhadas indesejadas e fator importante não só na solução de problemas pessoais de proprietários, mas também no controle populacional da espécie. Foram abordados os aspectos favoráveis e contra-indicações da interrupção cirúrgica e medicamentosa da prenhez. A interrupção cirúrgica é considerada a melhor escolha para animais que não se pretenda utilizar para reprodução. A utilização de estrógenos, do citrato de tamoxifena e agentes embriotóxicos não-hormonais é restringida pelos seus graves efeitos colaterais. A epostana necessita maiores estudos para confirmar sua eficiência. Apesar de possível, o uso dos análogos de GnRH esbarra em limitações de fornecimento e custo, assim como o controle imunológico da gestação, na especificidade dos agentes utilizados e possíveis efeitos colaterais, enquanto o uso de glicocorticóides, na duração do tratamento e efeitos secundários inerentes aos corticosteróides. Mifepristona e aglepristona, indisponíveis no mercado, têm sido apontadas como drogas de futuro promissor em face de sua eficácia, segurança e utilização em qualquer fase da gestação. Apesar dos seus previsíveis efeitos colaterais e da necessidade de hospitalização dos animais tratados, as prostaglandinas são cada vez mais utilizadas como drogas abortivas. Dentre os agonistas de dopamina, a cabergolina mostra os melhores resultados, principalmente quando associada ao análogo da prostaglandina cloprostenol, podendo ser utilizada assim que o diagnóstico de gestação seja possível, com eficiência de 100% e poucos efeitos colaterais.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2000-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/581910.1590/S1413-95962000000300009Brazilian Journal of Veterinary Research and Animal Science; Vol. 37 Núm. 3 (2000); 221-228Brazilian Journal of Veterinary Research and Animal Science; Vol. 37 No. 3 (2000); 221-228Brazilian Journal of Veterinary Research and Animal Science; v. 37 n. 3 (2000); 221-228Brazilian Journal of Veterinary Research and Animal Science; V. 37 N. 3 (2000); 221-2281678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/5819/62473Brunckhorst, Claudia StollVuono, Laudinor deBarnabe, Renato Camparanutinfo:eu-repo/semantics/openAccess2020-06-23T04:41:38Zoai:revistas.usp.br:article/5819Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:42:24.016435Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false
dc.title.none.fl_str_mv Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)
Interrupção eletiva da gestação em cães (Canis familiaris, Linnaeus, 1758)
title Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)
spellingShingle Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)
Brunckhorst, Claudia Stoll
Prenhez
Aborto
Cadelas
Pregnancy
Abortion
Bitches
title_short Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)
title_full Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)
title_fullStr Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)
title_full_unstemmed Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)
title_sort Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)
author Brunckhorst, Claudia Stoll
author_facet Brunckhorst, Claudia Stoll
Vuono, Laudinor de
Barnabe, Renato Camparanut
author_role author
author2 Vuono, Laudinor de
Barnabe, Renato Camparanut
author2_role author
author
dc.contributor.author.fl_str_mv Brunckhorst, Claudia Stoll
Vuono, Laudinor de
Barnabe, Renato Camparanut
dc.subject.por.fl_str_mv Prenhez
Aborto
Cadelas
Pregnancy
Abortion
Bitches
topic Prenhez
Aborto
Cadelas
Pregnancy
Abortion
Bitches
description The problem of the choice of a reliable and safe method of elective interruption of pregnancy in bitches was analysed. The methods are common in the small animal practice in preventing the birth of unwanted litters and are considered an important factor not only for the solution of owners personal problems, but also for this species population control. The favorable aspects and the counter indications of surgical and medicamental interruption of pregnancy were discussed. The surgical interruption is considered as the best choice for animals not intended to be utilized for reproduction. The serious side effects restricted the use of estrogens, tamoxifen citrate and non- hormonal embryotoxic agents. Epostane needs more studies to confirm its efficiency. Although possible, the utilization of analogues of GnRH still has supplying and cost limitations. The specificity of the used agents and their possible side effects limit immunological control of pregnancy. The use of glucocorticoids is limited through the length of the treatment and side effects. Mifepristone and aglepristone, commercially unavailable products, have been indicated as promising drugs in the future due to their efficiency, security and utilization during all stages of pregnancy. Despite the previsible side effects and the necessity of hospitalization for the treated animals, prostaglandins are more and more utilized as abortive drugs. Throughout dopamine agonists, cabergoline presents the best results, especially when associated with the analog of the prostaglandin cloprostenol. It can be used as soon as the diagnosis of pregnancy is possible, with 100% of efficiency and little side effects.
publishDate 2000
dc.date.none.fl_str_mv 2000-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/5819
10.1590/S1413-95962000000300009
url https://www.revistas.usp.br/bjvras/article/view/5819
identifier_str_mv 10.1590/S1413-95962000000300009
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/5819/62473
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science; Vol. 37 Núm. 3 (2000); 221-228
Brazilian Journal of Veterinary Research and Animal Science; Vol. 37 No. 3 (2000); 221-228
Brazilian Journal of Veterinary Research and Animal Science; v. 37 n. 3 (2000); 221-228
Brazilian Journal of Veterinary Research and Animal Science; V. 37 N. 3 (2000); 221-228
1678-4456
1413-9596
reponame:Brazilian Journal of Veterinary Research and Animal Science
instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron:USP
instname_str Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Veterinary Research and Animal Science
collection Brazilian Journal of Veterinary Research and Animal Science
repository.name.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
repository.mail.fl_str_mv bjvras@usp.br
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