Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Veterinary Research and Animal Science |
Texto Completo: | https://www.revistas.usp.br/bjvras/article/view/39970 |
Resumo: | The aim of this study was to evaluate the calcium phosphate, calcium pyrophosphate (CPP) with heat treatment at 700 and 900 ° C, tricalcium phosphate combined with hydroxyapatite (TCP/HA) and hydroxyapatite (HA) as bone substitutes. We used 20 rabbits (Oryctolagus cuniculus) of both sexes, New Zealand breed, with mean weigh of 2.5 ± 0.41 kg. The animals were randomly divided into two groups of 10 animals in the period in which they were euthanized (30 or 60 days). The implants were placed on the proximal and distal metaphysis of each femur so that CPP 700 and 900 were introduced in the left, while TCP/HA and HA in the right. Clinical and radiographic-surgical evaluations were performed immediately after surgery, and 30 and 60 days post-surgery. The animals showed normal clinical evolution. In the radiographic evaluation there was statistical difference between groups with higher degree of radiopacity at group 60 days that used TCP/HA and HA implants. In the histological evaluation by light microscopy and morphometric analysis the materials TCP/HA and HA showed greater one formation around the implants than CPP700 and CPP900 at 30 and 60-days evaluation. |
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USP-49 |
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Brazilian Journal of Veterinary Research and Animal Science |
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Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological studyAvaliação de diferentes proporções de fosfato de cálcio na regeneração do tecido ósseo de coelhos: estudo clínicocirúrgico, radiológico e histológicoBiomateriaisCicatrização ósseaCirurgiaBiomaterialsBone healingSurgeryThe aim of this study was to evaluate the calcium phosphate, calcium pyrophosphate (CPP) with heat treatment at 700 and 900 ° C, tricalcium phosphate combined with hydroxyapatite (TCP/HA) and hydroxyapatite (HA) as bone substitutes. We used 20 rabbits (Oryctolagus cuniculus) of both sexes, New Zealand breed, with mean weigh of 2.5 ± 0.41 kg. The animals were randomly divided into two groups of 10 animals in the period in which they were euthanized (30 or 60 days). The implants were placed on the proximal and distal metaphysis of each femur so that CPP 700 and 900 were introduced in the left, while TCP/HA and HA in the right. Clinical and radiographic-surgical evaluations were performed immediately after surgery, and 30 and 60 days post-surgery. The animals showed normal clinical evolution. In the radiographic evaluation there was statistical difference between groups with higher degree of radiopacity at group 60 days that used TCP/HA and HA implants. In the histological evaluation by light microscopy and morphometric analysis the materials TCP/HA and HA showed greater one formation around the implants than CPP700 and CPP900 at 30 and 60-days evaluation.O objetivo deste estudo foi avaliar os fosfatos de cálcio, pirofosfato de cálcio (CPP) com tratamento térmico a 700 e 900°C, fosfato tricálcio associado à hidroxiapatita (TCP/HA) e hidroxiapatita (HA) como substitutos ósseos. Foram utilizados 20 coelhos (Oryctolagus cuniculus), de ambos os sexos, da raça Nova Zelândia, pesando em média 2,5±0,41kg. Os animais foram distribuídos, ao acaso, em dois grupos de 10 animais de acordo com o período em que foram eutanasiados (30 ou 60 dias). Os implantes foram introduzidos na metáfise proximal e distal de cada fêmur, de modo que os CPP 700 e 900 foram introduzidos no membro esquerdo, enquanto o TCP/HA e HA no membro direito. Foram realizadas avaliações clínico-cirúrgicas e radiográficas imediatamente após a cirurgia e aos 30 e 60 dias do pós-operatório. Os animais apresentaram evolução clínica normal. Na avaliação radiográfica observou-se diferença estatística entre os grupos com maior grau de radiopacidade nos animais do grupo 60 dias que utilizaram os implantes TCP/HA e HA. Na avaliação histológica, por meio de microscopia de luz e análise morfométrica, os materiais TCP/HA e HA proporcionaram maior neoformação óssea ao redor dos implantes do que com os CPP700 e CPP900 aos 30 e 60 dias de avaliação.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2012-02-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/3997010.11606/issn.2318-3659.v49i1p12-18Brazilian Journal of Veterinary Research and Animal Science; Vol. 49 Núm. 1 (2012); 12-18Brazilian Journal of Veterinary Research and Animal Science; Vol. 49 No. 1 (2012); 12-18Brazilian Journal of Veterinary Research and Animal Science; v. 49 n. 1 (2012); 12-18Brazilian Journal of Veterinary Research and Animal Science; V. 49 N. 1 (2012); 12-181678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/39970/42834Azevedo, Adilío Santos deSá, Marcelo Jorge Cavalcanti deCosta Neto, Pedro Isidro daFook, Marcus Vinícius LiaPortela, Roseane de AraújoAzevedo, Sérgio Santos deinfo:eu-repo/semantics/openAccess2020-06-23T04:08:47Zoai:revistas.usp.br:article/39970Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:43:12.758196Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false |
dc.title.none.fl_str_mv |
Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study Avaliação de diferentes proporções de fosfato de cálcio na regeneração do tecido ósseo de coelhos: estudo clínicocirúrgico, radiológico e histológico |
title |
Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study |
spellingShingle |
Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study Azevedo, Adilío Santos de Biomateriais Cicatrização óssea Cirurgia Biomaterials Bone healing Surgery |
title_short |
Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study |
title_full |
Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study |
title_fullStr |
Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study |
title_full_unstemmed |
Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study |
title_sort |
Evaluation of different proportions of calcium phosphate in the regeneration of bone tissue of rabbits: clinical-surgical, radiological and histological study |
author |
Azevedo, Adilío Santos de |
author_facet |
Azevedo, Adilío Santos de Sá, Marcelo Jorge Cavalcanti de Costa Neto, Pedro Isidro da Fook, Marcus Vinícius Lia Portela, Roseane de Araújo Azevedo, Sérgio Santos de |
author_role |
author |
author2 |
Sá, Marcelo Jorge Cavalcanti de Costa Neto, Pedro Isidro da Fook, Marcus Vinícius Lia Portela, Roseane de Araújo Azevedo, Sérgio Santos de |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Azevedo, Adilío Santos de Sá, Marcelo Jorge Cavalcanti de Costa Neto, Pedro Isidro da Fook, Marcus Vinícius Lia Portela, Roseane de Araújo Azevedo, Sérgio Santos de |
dc.subject.por.fl_str_mv |
Biomateriais Cicatrização óssea Cirurgia Biomaterials Bone healing Surgery |
topic |
Biomateriais Cicatrização óssea Cirurgia Biomaterials Bone healing Surgery |
description |
The aim of this study was to evaluate the calcium phosphate, calcium pyrophosphate (CPP) with heat treatment at 700 and 900 ° C, tricalcium phosphate combined with hydroxyapatite (TCP/HA) and hydroxyapatite (HA) as bone substitutes. We used 20 rabbits (Oryctolagus cuniculus) of both sexes, New Zealand breed, with mean weigh of 2.5 ± 0.41 kg. The animals were randomly divided into two groups of 10 animals in the period in which they were euthanized (30 or 60 days). The implants were placed on the proximal and distal metaphysis of each femur so that CPP 700 and 900 were introduced in the left, while TCP/HA and HA in the right. Clinical and radiographic-surgical evaluations were performed immediately after surgery, and 30 and 60 days post-surgery. The animals showed normal clinical evolution. In the radiographic evaluation there was statistical difference between groups with higher degree of radiopacity at group 60 days that used TCP/HA and HA implants. In the histological evaluation by light microscopy and morphometric analysis the materials TCP/HA and HA showed greater one formation around the implants than CPP700 and CPP900 at 30 and 60-days evaluation. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-02-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/39970 10.11606/issn.2318-3659.v49i1p12-18 |
url |
https://www.revistas.usp.br/bjvras/article/view/39970 |
identifier_str_mv |
10.11606/issn.2318-3659.v49i1p12-18 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/39970/42834 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science; Vol. 49 Núm. 1 (2012); 12-18 Brazilian Journal of Veterinary Research and Animal Science; Vol. 49 No. 1 (2012); 12-18 Brazilian Journal of Veterinary Research and Animal Science; v. 49 n. 1 (2012); 12-18 Brazilian Journal of Veterinary Research and Animal Science; V. 49 N. 1 (2012); 12-18 1678-4456 1413-9596 reponame:Brazilian Journal of Veterinary Research and Animal Science instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) instacron:USP |
instname_str |
Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Brazilian Journal of Veterinary Research and Animal Science |
collection |
Brazilian Journal of Veterinary Research and Animal Science |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
repository.mail.fl_str_mv |
bjvras@usp.br |
_version_ |
1797051554074722304 |