Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil

Detalhes bibliográficos
Autor(a) principal: Costa, Heni Falcão da
Data de Publicação: 2012
Outros Autores: Stachissini, Anne Valéria Mendonça, Langoni, Hélio, Padovani, Carlos Roberto, Gennari, Solange Maria, Modolo, José Rafael
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
Texto Completo: https://www.revistas.usp.br/bjvras/article/view/40261
Resumo: This study aimed at assessing the occurrence of antibodies against the caprine arthritis-encephalitis virus (CAEV), Toxoplasma gondii and Neospora caninum, as well as the associations between the presence of antibodies and the occurrence of reproductive failures in goats. Serum samples were collected from 923 goats of both sexes, over 3 months of age, from 17 dairy farms located in different municipalities of São Paulo State, Brazil. Infections by T. gondii, N. caninum and CAEV were evaluated by indirect methods of diagnosis based on indirect fluorescence antibody test (IFAT), Neospora agglutination test (NAT), and agar gel immunodiffusion (AGID), respectively. A survey was conducted on the farms to obtain information about reproduction dates (abortions, stillbirths and births of weak and premature kids) and zoosanitary management. Antibodies against CAEV, T. gondii and N. caninum was found in 37.81%, 23.62% and 17.23% respectively. There was no significant association between the presence of anti-CAEV antibodies and CAEV/T. gondii or CAEV/N. caninum co-infection, suggesting that CAEV does not predispose goats to infection by these agents. However, when CAEV/T. gondii (p<0.01) or CAEV/N. caninum (p<0.001) co-infection was present, the occurrence of reproductive failures was significantly higher what could indicate that CAEV-induced immunosuppression may predispose goats to develop the clinical symptoms of toxoplasmosis and neosporosis increasing the risks of the reproductive failures.
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spelling Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, BrazilFalhas reprodutivas associadas com a presença de do vírus da artrite-encefalite caprina, Toxoplasma gondii e Neospora caninum em caprinos no estado de São Paulo, BrasilCaprinoCAEVToxoplasma gondiiNeospora caninumFalhas reprodutivasGoatCAEVToxoplasma gondiiNeospora caninumCo-infectionReproductive failuresThis study aimed at assessing the occurrence of antibodies against the caprine arthritis-encephalitis virus (CAEV), Toxoplasma gondii and Neospora caninum, as well as the associations between the presence of antibodies and the occurrence of reproductive failures in goats. Serum samples were collected from 923 goats of both sexes, over 3 months of age, from 17 dairy farms located in different municipalities of São Paulo State, Brazil. Infections by T. gondii, N. caninum and CAEV were evaluated by indirect methods of diagnosis based on indirect fluorescence antibody test (IFAT), Neospora agglutination test (NAT), and agar gel immunodiffusion (AGID), respectively. A survey was conducted on the farms to obtain information about reproduction dates (abortions, stillbirths and births of weak and premature kids) and zoosanitary management. Antibodies against CAEV, T. gondii and N. caninum was found in 37.81%, 23.62% and 17.23% respectively. There was no significant association between the presence of anti-CAEV antibodies and CAEV/T. gondii or CAEV/N. caninum co-infection, suggesting that CAEV does not predispose goats to infection by these agents. However, when CAEV/T. gondii (p<0.01) or CAEV/N. caninum (p<0.001) co-infection was present, the occurrence of reproductive failures was significantly higher what could indicate that CAEV-induced immunosuppression may predispose goats to develop the clinical symptoms of toxoplasmosis and neosporosis increasing the risks of the reproductive failures.O objetivo do presente estudo foi avaliar a ocorrência de anticorpos para o vírus da atrite-encefalite caprina (CAEV), Toxoplasma gondii e Neospora caninum e de possíveis associações entre a presença de anticorpos e a ocorrência de problemas reprodutivos em caprinos. Para tanto, foram colhidas amostras sangüíneas de 923 caprinos de ambos os sexos, acima de três meses de idade e oriundos de 17 propriedades leiteiras, de diferentes municípios do estado de São Paulo, Brasil. Os diagnósticos para T. gondii, N. caninum e CAEV foram baseados, respectivamente, na reação de imunofluorescência indireta (RIFI), teste de aglutinação para Neospora (NAT) e a imunodifusão em gel de ágar (IDGA). Um inquérito epidemiológico foi aplicado nas propriedades para obtenção de informações sobre dados reprodutivos (abortamentos, natimortalidade e nascimentos de filhotes fracos e prematuros) e de manejo zoossanitário. As ocorrências de anticorpos foram de 37,81% para CAEV, de 23,62% para T. gondii e de 17,23% para N. caninum. Não houve associação significativa entre a presença de anticorpos anti-CAEV e co-infecção com T. gondii ou N. caninum, sugerindo que o CAEV não predispõe os caprinos à infecção por estes agentes. Entretanto, quando havia, nas fazendas, animais com co-infecção pelo CAEV e T. gondii (p<0,01) ou CAEV e N. caninum (p<0,001) as ocorrências de falhas reprodutivas foram significativamente maiores, sugerindo que a imunossupressão causada pelo CAEV pode predispor os caprinos ao desenvolvimento de sintomas clínicos da toxoplasmose e neosporose, potencializando os riscos da ocorrência de problemas reprodutivos causados por estas enfermidades.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2012-02-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/4026110.11606/issn.2318-3659.v49i1p67-72Brazilian Journal of Veterinary Research and Animal Science; Vol. 49 Núm. 1 (2012); 67-72Brazilian Journal of Veterinary Research and Animal Science; Vol. 49 No. 1 (2012); 67-72Brazilian Journal of Veterinary Research and Animal Science; v. 49 n. 1 (2012); 67-72Brazilian Journal of Veterinary Research and Animal Science; V. 49 N. 1 (2012); 67-721678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPenghttps://www.revistas.usp.br/bjvras/article/view/40261/43127Costa, Heni Falcão daStachissini, Anne Valéria MendonçaLangoni, HélioPadovani, Carlos RobertoGennari, Solange MariaModolo, José Rafaelinfo:eu-repo/semantics/openAccess2020-06-23T04:08:39Zoai:revistas.usp.br:article/40261Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:43:13.161467Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false
dc.title.none.fl_str_mv Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil
Falhas reprodutivas associadas com a presença de do vírus da artrite-encefalite caprina, Toxoplasma gondii e Neospora caninum em caprinos no estado de São Paulo, Brasil
title Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil
spellingShingle Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil
Costa, Heni Falcão da
Caprino
CAEV
Toxoplasma gondii
Neospora caninum
Falhas reprodutivas
Goat
CAEV
Toxoplasma gondii
Neospora caninum
Co-infection
Reproductive failures
title_short Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil
title_full Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil
title_fullStr Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil
title_full_unstemmed Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil
title_sort Reproductive failures associated with antibodies against caprine arthritis-encephalitis virus, Toxoplasma gondii and Neospora caninum in goats in the state of Sao Paulo, Brazil
author Costa, Heni Falcão da
author_facet Costa, Heni Falcão da
Stachissini, Anne Valéria Mendonça
Langoni, Hélio
Padovani, Carlos Roberto
Gennari, Solange Maria
Modolo, José Rafael
author_role author
author2 Stachissini, Anne Valéria Mendonça
Langoni, Hélio
Padovani, Carlos Roberto
Gennari, Solange Maria
Modolo, José Rafael
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Costa, Heni Falcão da
Stachissini, Anne Valéria Mendonça
Langoni, Hélio
Padovani, Carlos Roberto
Gennari, Solange Maria
Modolo, José Rafael
dc.subject.por.fl_str_mv Caprino
CAEV
Toxoplasma gondii
Neospora caninum
Falhas reprodutivas
Goat
CAEV
Toxoplasma gondii
Neospora caninum
Co-infection
Reproductive failures
topic Caprino
CAEV
Toxoplasma gondii
Neospora caninum
Falhas reprodutivas
Goat
CAEV
Toxoplasma gondii
Neospora caninum
Co-infection
Reproductive failures
description This study aimed at assessing the occurrence of antibodies against the caprine arthritis-encephalitis virus (CAEV), Toxoplasma gondii and Neospora caninum, as well as the associations between the presence of antibodies and the occurrence of reproductive failures in goats. Serum samples were collected from 923 goats of both sexes, over 3 months of age, from 17 dairy farms located in different municipalities of São Paulo State, Brazil. Infections by T. gondii, N. caninum and CAEV were evaluated by indirect methods of diagnosis based on indirect fluorescence antibody test (IFAT), Neospora agglutination test (NAT), and agar gel immunodiffusion (AGID), respectively. A survey was conducted on the farms to obtain information about reproduction dates (abortions, stillbirths and births of weak and premature kids) and zoosanitary management. Antibodies against CAEV, T. gondii and N. caninum was found in 37.81%, 23.62% and 17.23% respectively. There was no significant association between the presence of anti-CAEV antibodies and CAEV/T. gondii or CAEV/N. caninum co-infection, suggesting that CAEV does not predispose goats to infection by these agents. However, when CAEV/T. gondii (p<0.01) or CAEV/N. caninum (p<0.001) co-infection was present, the occurrence of reproductive failures was significantly higher what could indicate that CAEV-induced immunosuppression may predispose goats to develop the clinical symptoms of toxoplasmosis and neosporosis increasing the risks of the reproductive failures.
publishDate 2012
dc.date.none.fl_str_mv 2012-02-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/40261
10.11606/issn.2318-3659.v49i1p67-72
url https://www.revistas.usp.br/bjvras/article/view/40261
identifier_str_mv 10.11606/issn.2318-3659.v49i1p67-72
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/40261/43127
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science; Vol. 49 Núm. 1 (2012); 67-72
Brazilian Journal of Veterinary Research and Animal Science; Vol. 49 No. 1 (2012); 67-72
Brazilian Journal of Veterinary Research and Animal Science; v. 49 n. 1 (2012); 67-72
Brazilian Journal of Veterinary Research and Animal Science; V. 49 N. 1 (2012); 67-72
1678-4456
1413-9596
reponame:Brazilian Journal of Veterinary Research and Animal Science
instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron:USP
instname_str Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Veterinary Research and Animal Science
collection Brazilian Journal of Veterinary Research and Animal Science
repository.name.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
repository.mail.fl_str_mv bjvras@usp.br
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