Infecção sistêmica por Spencermartinsiella sp. em um crocodilo do Nilo (Crocodylus niloticus)

• Autor(a) principal: Carvalho, Tatiane Furtado de
• Data de Publicação: 2017
• Outros Autores: Tinoco, Herlandes Penha, Malta, Marcelo Cordeiro Campos, Pessanha, Angela Tinoco, Matos, Thelma Tirone Silvério, Rocha, Cláudia Emanuela, Gomes, Priscilla Parreira Rocha, Garcia, Luize Néli Nunes, Frois, Daniella Noronha, Pereira, Marianna de Paula Martins, Johann, Susana, Rosa, Carlos Augusto, Paixão, Tatiane Alves da, Santos, Renato Lima
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
• Texto Completo: https://www.revistas.usp.br/bjvras/article/view/109058
• topic: Crocodile; Crocodylus niloticus; Candidiasis; Spencermartinsiella sp; Crocodilo; Crocodylus niloticus; Candidíase; Spencermartinsiella sp

A male adult crocodile (Crocodylus niloticus) was diagnosed with systemic yeast infection. Histologically, there were extensive areas of necrosis in the lung, which were associated with a diffuse severe lympho-plasmo-histiocytic inflammatory infiltrate, with numerous multinucleated giant cells, and myriads of intralesional pseudo-hyphae and yeast like organisms within distended foveolae. Necrotic foci were also observed in the mucosa of the digestive tract, trachea, tunica intima of arteries, liver, and heart, with a marked inflammatory lympho-histiocytic infiltrate, with large numbers of epithelioid macrophages and giant cells, and intralesional and intravascular pseudo-hyphae and yeast-like organisms. Oval yeast structures with 4 to 6 μm in diameter and 5 to 8 μm thick paralleled-wall pseudo-hyphae were observed in PAS or GMS stained sections. PCR with DNA template extracted from paraffin embedded tissues amplified the D1/D2 domains of the large subunit rRNA gene, which was sequenced and found to be identical to sequences of a new species, isolated from rotting wood in Brazil, of the genus Spencermartinsiella, which its closest relative is Spencermartinsiella cellulosicola.