Toxoplasma gondii: I. Evaluation of the virulence of eight strains
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Veterinary Research and Animal Science |
Texto Completo: | https://www.revistas.usp.br/bjvras/article/view/5666 |
Resumo: | In order to evaluate the virulence and pathogenicity of tachyzoites, eight Toxoplasma gondii strains isolated from different animal species and humans - LIV IV, LIV V e S 11 isolated from swine, RH e VPS from humans, AS 28 from mice, HV III from dog and CN from cat - were inoculated in mice and rabbits. All the strains were strongly virulent for mice. Groups of mice inoculated, intraperitonially, with 10(4) tachyzoites died in an average of 6.0 to 7.8 days, after inoculation. The strains isolated more recently, LIV V and HV III (LD50 of 7 and 15 tachyzoites, respectively) were the most virulent. The RH strain showed the lowest virulence, with LD50 of 3160 tachyzoites. The LIV V strain also seems to be most virulent to rabbits. |
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Brazilian Journal of Veterinary Research and Animal Science |
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Toxoplasma gondii: I. Evaluation of the virulence of eight strainsToxoplasma gondii: I. Avaliação da virulência de oito amostrasToxoplasma gondiiPatogenicidadeAnimais de laboratórioToxoplasma gondiiPathogenicityLaboratory animalsIn order to evaluate the virulence and pathogenicity of tachyzoites, eight Toxoplasma gondii strains isolated from different animal species and humans - LIV IV, LIV V e S 11 isolated from swine, RH e VPS from humans, AS 28 from mice, HV III from dog and CN from cat - were inoculated in mice and rabbits. All the strains were strongly virulent for mice. Groups of mice inoculated, intraperitonially, with 10(4) tachyzoites died in an average of 6.0 to 7.8 days, after inoculation. The strains isolated more recently, LIV V and HV III (LD50 of 7 and 15 tachyzoites, respectively) were the most virulent. The RH strain showed the lowest virulence, with LD50 of 3160 tachyzoites. The LIV V strain also seems to be most virulent to rabbits.Oito amostras de T. gondii - LIV IV, LIV V e S 11 isoladas de suínos, RH e VPS de seres humanos, AS 28 de camundongo, HV III de cão e CN de gato - foram inoculadas em camundongos suíços albinos e em coelhos com o objetivo de avaliar a virulência e a patogenicidade. As oito amostras apresentaram-se altamente virulentas para camundongos, matando todos os animais que receberam inóculo, via intraperitoneal, de 10(4) taquizoítas, entre 6,0 e 7,8 dias, em média, após a inoculação. As amostras isoladas mais recentemente, LIV V e HV III (DL50 de 7 e 15 taquizoítas, respectivamente) foram as mais virulentas. A amostra RH foi a que apresentou a menor virulência, com DL50 de 3.160 taquizoítas. A amostra LIV V também se mostrou mais virulenta para coelhos, porém, como foram inoculados apenas 2 animais, estudos posteriores devem ser realizados para confirmar este achado.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia1998-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/566610.1590/S1413-95961998000100005Brazilian Journal of Veterinary Research and Animal Science; Vol. 35 Núm. 1 (1998); 29-31Brazilian Journal of Veterinary Research and Animal Science; Vol. 35 No. 1 (1998); 29-31Brazilian Journal of Veterinary Research and Animal Science; v. 35 n. 1 (1998); 29-31Brazilian Journal of Veterinary Research and Animal Science; V. 35 N. 1 (1998); 29-311678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/5666/7197Mitsuka, ReginaBeckner da Silva, Andrea CristinaNavarro, Italmar TeodoricoBreganó, José WanderVidotto, Odiloninfo:eu-repo/semantics/openAccess2020-06-23T04:46:43Zoai:revistas.usp.br:article/5666Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:42:16.198221Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false |
dc.title.none.fl_str_mv |
Toxoplasma gondii: I. Evaluation of the virulence of eight strains Toxoplasma gondii: I. Avaliação da virulência de oito amostras |
title |
Toxoplasma gondii: I. Evaluation of the virulence of eight strains |
spellingShingle |
Toxoplasma gondii: I. Evaluation of the virulence of eight strains Mitsuka, Regina Toxoplasma gondii Patogenicidade Animais de laboratório Toxoplasma gondii Pathogenicity Laboratory animals |
title_short |
Toxoplasma gondii: I. Evaluation of the virulence of eight strains |
title_full |
Toxoplasma gondii: I. Evaluation of the virulence of eight strains |
title_fullStr |
Toxoplasma gondii: I. Evaluation of the virulence of eight strains |
title_full_unstemmed |
Toxoplasma gondii: I. Evaluation of the virulence of eight strains |
title_sort |
Toxoplasma gondii: I. Evaluation of the virulence of eight strains |
author |
Mitsuka, Regina |
author_facet |
Mitsuka, Regina Beckner da Silva, Andrea Cristina Navarro, Italmar Teodorico Breganó, José Wander Vidotto, Odilon |
author_role |
author |
author2 |
Beckner da Silva, Andrea Cristina Navarro, Italmar Teodorico Breganó, José Wander Vidotto, Odilon |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Mitsuka, Regina Beckner da Silva, Andrea Cristina Navarro, Italmar Teodorico Breganó, José Wander Vidotto, Odilon |
dc.subject.por.fl_str_mv |
Toxoplasma gondii Patogenicidade Animais de laboratório Toxoplasma gondii Pathogenicity Laboratory animals |
topic |
Toxoplasma gondii Patogenicidade Animais de laboratório Toxoplasma gondii Pathogenicity Laboratory animals |
description |
In order to evaluate the virulence and pathogenicity of tachyzoites, eight Toxoplasma gondii strains isolated from different animal species and humans - LIV IV, LIV V e S 11 isolated from swine, RH e VPS from humans, AS 28 from mice, HV III from dog and CN from cat - were inoculated in mice and rabbits. All the strains were strongly virulent for mice. Groups of mice inoculated, intraperitonially, with 10(4) tachyzoites died in an average of 6.0 to 7.8 days, after inoculation. The strains isolated more recently, LIV V and HV III (LD50 of 7 and 15 tachyzoites, respectively) were the most virulent. The RH strain showed the lowest virulence, with LD50 of 3160 tachyzoites. The LIV V strain also seems to be most virulent to rabbits. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/5666 10.1590/S1413-95961998000100005 |
url |
https://www.revistas.usp.br/bjvras/article/view/5666 |
identifier_str_mv |
10.1590/S1413-95961998000100005 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/5666/7197 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science; Vol. 35 Núm. 1 (1998); 29-31 Brazilian Journal of Veterinary Research and Animal Science; Vol. 35 No. 1 (1998); 29-31 Brazilian Journal of Veterinary Research and Animal Science; v. 35 n. 1 (1998); 29-31 Brazilian Journal of Veterinary Research and Animal Science; V. 35 N. 1 (1998); 29-31 1678-4456 1413-9596 reponame:Brazilian Journal of Veterinary Research and Animal Science instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) instacron:USP |
instname_str |
Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Brazilian Journal of Veterinary Research and Animal Science |
collection |
Brazilian Journal of Veterinary Research and Animal Science |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
repository.mail.fl_str_mv |
bjvras@usp.br |
_version_ |
1797051554048507904 |