Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis

Detalhes bibliográficos
Autor(a) principal: Costa, Fabiano Séllos
Data de Publicação: 2009
Outros Autores: Cardoso, Mauro José Lahm, Muniz, Lucy Marie Ribeiro, Vulcano, Luiz Carlos, Ramos, Paulo Roberto Rodrigues, Justulin Junior, Luís Antonio, Felisbino, Sérgio Luís, Santos, Warley Gomes dos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
Texto Completo: https://www.revistas.usp.br/bjvras/article/view/26788
Resumo: Thyrotoxicosis, characterized by excessive serum levels of thyroid hormones, can cause serious effects in bone metabolism, elevating the total alkaline phosphatase, which is a frequent laboratorial alteration observed in feline hyperthyroidism. A rise in total serum levels of alkaline phosphatase can be caused by different isoenzymes, and in human hyperthyroidism, bone and hepatic isoenzymes are commonly increased. After serum biochemical evaluation of eight cats with induced thyrotoxicosis and associated elevation of alkaline phosphatase, the present paper shows a significant elevation of bone isoenzyme serum levels when compared with hepatic isoenzyme. It was possible to conclude that bone metabolism alterations were the main responsible for the increase of serum alkaline phosphatase in cats with induced thyrotoxicosis.
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spelling Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosisAvaliação da fosfatase alcalina óssea e hepática em gatos com tirotoxicose induzidaFosfatase alcalinaIsoenzimaHipertiroidismoGatoAlkaline phosphataseIsoenzymeHyperthyroidismCatThyrotoxicosis, characterized by excessive serum levels of thyroid hormones, can cause serious effects in bone metabolism, elevating the total alkaline phosphatase, which is a frequent laboratorial alteration observed in feline hyperthyroidism. A rise in total serum levels of alkaline phosphatase can be caused by different isoenzymes, and in human hyperthyroidism, bone and hepatic isoenzymes are commonly increased. After serum biochemical evaluation of eight cats with induced thyrotoxicosis and associated elevation of alkaline phosphatase, the present paper shows a significant elevation of bone isoenzyme serum levels when compared with hepatic isoenzyme. It was possible to conclude that bone metabolism alterations were the main responsible for the increase of serum alkaline phosphatase in cats with induced thyrotoxicosis.A tirotoxicose é caracterizada pelas excessivas concentrações séricas dos hormônios tiroidianos, podendo desencadear graves alterações no metabolismo ósseo, sendo a elevação da fosfatase alcalina total uma alteração laboratorial freqüentemente observada no hipertiroidismo felino. O aumento global dos níveis séricos de fosfatase alcalina pode ser decorrente de diferentes isoenzimas e, no caso do hipertiroidismo em humanos, as isoenzimas de origem óssea e hepática apresentam-se comumente elevadas. A partir da avaliação da bioquímica sérica de oito gatos com tirotoxicose induzida e elevação da fosfatase alcalina associada, o presente trabalho demonstra um aumento significativamente maior dos níveis séricos da fosfatase alcalina de origem óssea quando comparado com a isoenzima de origem hepática. Conclui-se que as alterações no metabolismo ósseo foram as principais responsáveis pelo aumento da fosfatase alcalina nos gatos com tirotoxicose induzida.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2009-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/2678810.11606/issn.1678-4456.bjvras.2009.26788Brazilian Journal of Veterinary Research and Animal Science; Vol. 46 Núm. 5 (2009); 387-394 Brazilian Journal of Veterinary Research and Animal Science; Vol. 46 No. 5 (2009); 387-394 Brazilian Journal of Veterinary Research and Animal Science; v. 46 n. 5 (2009); 387-394 Brazilian Journal of Veterinary Research and Animal Science; V. 46 N. 5 (2009); 387-394 1678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/26788/28571Costa, Fabiano SéllosCardoso, Mauro José LahmMuniz, Lucy Marie RibeiroVulcano, Luiz CarlosRamos, Paulo Roberto RodriguesJustulin Junior, Luís AntonioFelisbino, Sérgio LuísSantos, Warley Gomes dosinfo:eu-repo/semantics/openAccess2020-06-23T04:11:24Zoai:revistas.usp.br:article/26788Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:43:03.958747Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false
dc.title.none.fl_str_mv Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis
Avaliação da fosfatase alcalina óssea e hepática em gatos com tirotoxicose induzida
title Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis
spellingShingle Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis
Costa, Fabiano Séllos
Fosfatase alcalina
Isoenzima
Hipertiroidismo
Gato
Alkaline phosphatase
Isoenzyme
Hyperthyroidism
Cat
title_short Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis
title_full Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis
title_fullStr Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis
title_full_unstemmed Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis
title_sort Evaluation of bone and liver alkaline phosphatase in cats with induced thyrotoxicosis
author Costa, Fabiano Séllos
author_facet Costa, Fabiano Séllos
Cardoso, Mauro José Lahm
Muniz, Lucy Marie Ribeiro
Vulcano, Luiz Carlos
Ramos, Paulo Roberto Rodrigues
Justulin Junior, Luís Antonio
Felisbino, Sérgio Luís
Santos, Warley Gomes dos
author_role author
author2 Cardoso, Mauro José Lahm
Muniz, Lucy Marie Ribeiro
Vulcano, Luiz Carlos
Ramos, Paulo Roberto Rodrigues
Justulin Junior, Luís Antonio
Felisbino, Sérgio Luís
Santos, Warley Gomes dos
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Costa, Fabiano Séllos
Cardoso, Mauro José Lahm
Muniz, Lucy Marie Ribeiro
Vulcano, Luiz Carlos
Ramos, Paulo Roberto Rodrigues
Justulin Junior, Luís Antonio
Felisbino, Sérgio Luís
Santos, Warley Gomes dos
dc.subject.por.fl_str_mv Fosfatase alcalina
Isoenzima
Hipertiroidismo
Gato
Alkaline phosphatase
Isoenzyme
Hyperthyroidism
Cat
topic Fosfatase alcalina
Isoenzima
Hipertiroidismo
Gato
Alkaline phosphatase
Isoenzyme
Hyperthyroidism
Cat
description Thyrotoxicosis, characterized by excessive serum levels of thyroid hormones, can cause serious effects in bone metabolism, elevating the total alkaline phosphatase, which is a frequent laboratorial alteration observed in feline hyperthyroidism. A rise in total serum levels of alkaline phosphatase can be caused by different isoenzymes, and in human hyperthyroidism, bone and hepatic isoenzymes are commonly increased. After serum biochemical evaluation of eight cats with induced thyrotoxicosis and associated elevation of alkaline phosphatase, the present paper shows a significant elevation of bone isoenzyme serum levels when compared with hepatic isoenzyme. It was possible to conclude that bone metabolism alterations were the main responsible for the increase of serum alkaline phosphatase in cats with induced thyrotoxicosis.
publishDate 2009
dc.date.none.fl_str_mv 2009-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/26788
10.11606/issn.1678-4456.bjvras.2009.26788
url https://www.revistas.usp.br/bjvras/article/view/26788
identifier_str_mv 10.11606/issn.1678-4456.bjvras.2009.26788
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/26788/28571
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science; Vol. 46 Núm. 5 (2009); 387-394
Brazilian Journal of Veterinary Research and Animal Science; Vol. 46 No. 5 (2009); 387-394
Brazilian Journal of Veterinary Research and Animal Science; v. 46 n. 5 (2009); 387-394
Brazilian Journal of Veterinary Research and Animal Science; V. 46 N. 5 (2009); 387-394
1678-4456
1413-9596
reponame:Brazilian Journal of Veterinary Research and Animal Science
instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron:USP
instname_str Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Veterinary Research and Animal Science
collection Brazilian Journal of Veterinary Research and Animal Science
repository.name.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
repository.mail.fl_str_mv bjvras@usp.br
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