Anátomo histopathologic evaluation of the effect of medroxiprogesterone acetate and megestrol acetate on the uterus of adult bitches

• Autor(a) principal: Vicente, Wilter Ricardo Russiano
• Data de Publicação: 1991
• Outros Autores: Toniollo, Gilson Hélio, Sobreira, Lucia Ferreira da Rosa, Laus, José Luiz, Silva, Valéria Maria Saboya da, Moraes, Flávio Ruas de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
• Texto Completo: https://www.revistas.usp.br/bjvras/article/view/51941
• topic: Endometrite (cães); Medroxiprogesterona; Megestrol; Hedroxi progesterone acetate; Megestrol acetate; Endometritis of bitches

In this trial, 18 adult clinically sound bitches, without clinical symptoms of estrus were utilized, being randomly assigned in 6 groups with 3 animals each. After uterine biopsy for control, medroxiprogesterone acetate was injected into females of the group I, II and III, and megestrol acetate into females of the group IV, V and VI. It was observed that both drugs were capable in inducing endometritis, but this effect was more discrete in the animals of group IV, V and VI. The occurrence of poliuria, polidipsia, abdominal distention, purulent or bloody vaginal secretion, leucocitosis or anemia was not recorded.