Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits

Detalhes bibliográficos
Autor(a) principal: Schwarz, Aline
Data de Publicação: 2009
Outros Autores: Kempinas, Wilma De Grava, Soares, Milena Rodrigues, Bernardi, Maria Martha, Spinosa, Helenice de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
Texto Completo: https://www.revistas.usp.br/bjvras/article/view/26762
Resumo: This work employed pregnant rats treated with Solanum lycocarpum unripe fruits (10% in diet) from gestation day (GD) 06 to post-natal day (PND) 07, for the evaluation of the sperm number, daily sperm production and epididymal sperm transit time of the male offspring at PND 60 and PND 90. No differences were observed in the daily sperm production (DSP) and sperm number in the testis of the exposed males at PND 60 and PND 90. Also, no alterations were observed in sperm transit time in the caput epididymis of the exposed males at PND 60 and PND 90. However, a reduced sperm transit time was observed in the corpus/cauda epididymis of the experimental males at PND 90. The last data may explain the reduced sperm number observed in the corpus/cauda epididymis of the experimental male rats at PND 90. These data show that the male rats exposed to S. lycocarpum fruits during gestation did not present alterations in testis sperm production and number, however the sperm transit time through epididymis was impaired, resulting in a decreased number of spermatozoa in epididymis cauda. We conclude that S. lycocarpum may cause imbalance on hypothalamus-pituitary gland axis
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spelling Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruitsAlterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpumSolanum lycocarpumSolasodinaFunção reprodutivaFertilidadeProdução espermáticaRatoSolanum lycocarpumSolasodineReproductive functionFertilitySperm productionRatThis work employed pregnant rats treated with Solanum lycocarpum unripe fruits (10% in diet) from gestation day (GD) 06 to post-natal day (PND) 07, for the evaluation of the sperm number, daily sperm production and epididymal sperm transit time of the male offspring at PND 60 and PND 90. No differences were observed in the daily sperm production (DSP) and sperm number in the testis of the exposed males at PND 60 and PND 90. Also, no alterations were observed in sperm transit time in the caput epididymis of the exposed males at PND 60 and PND 90. However, a reduced sperm transit time was observed in the corpus/cauda epididymis of the experimental males at PND 90. The last data may explain the reduced sperm number observed in the corpus/cauda epididymis of the experimental male rats at PND 90. These data show that the male rats exposed to S. lycocarpum fruits during gestation did not present alterations in testis sperm production and number, however the sperm transit time through epididymis was impaired, resulting in a decreased number of spermatozoa in epididymis cauda. We conclude that S. lycocarpum may cause imbalance on hypothalamus-pituitary gland axisRatas prenhes foram tratadas do dia 06 da gestação (GD 06) ao dia 07 pós-natal (PND 07) com frutos verdes secos e moídos da Solanum lycocarpum (10% na ração). Após nascimento das ninhadas, foi avaliado na prole masculina adulta aos 60 e 90 dias de vida, o número de espermátides e a produção espermática diária nos testículos e o tempo de trânsito espermático no epidídimo. A exposição não foi capaz de promover alterações na produção espermática diária (DSP) e no número de espermátides produzidas pelo testículo dos ratos expostos aos frutos verdes da S. lycocarpum durante a gestação e início da lactação. Não foram observadas alterações no tempo de trânsito espermático na cabeça do epidídimo, porém, foi constatado menor número de espermatozóides no corpo/cauda do epidídimo nos machos experimentais com 90 dias de vida, provavelmente resultante do menor tempo de trânsito espermático observado no corpo/cauda do epidídimo aos PND 90. Estes dados sugerem que a exposição de ratos aos frutos verdes da S. lycocarpum durante a gestação e início da lactação, não foi suficiente para promover alterações na produção mas sim no trânsito espermático, indicando possível alteração no eixo hormônio liberador das gonadotrofinas hipotálamo-hipófise-gônadaUniversidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2009-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/2676210.11606/issn.1678-4456.bjvras.2009.26762Brazilian Journal of Veterinary Research and Animal Science; Vol. 46 Núm. 2 (2009); 152-157 Brazilian Journal of Veterinary Research and Animal Science; Vol. 46 No. 2 (2009); 152-157 Brazilian Journal of Veterinary Research and Animal Science; v. 46 n. 2 (2009); 152-157 Brazilian Journal of Veterinary Research and Animal Science; V. 46 N. 2 (2009); 152-157 1678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPenghttps://www.revistas.usp.br/bjvras/article/view/26762/28545Schwarz, AlineKempinas, Wilma De GravaSoares, Milena RodriguesBernardi, Maria MarthaSpinosa, Helenice de Souzainfo:eu-repo/semantics/openAccess2020-06-23T04:11:55Zoai:revistas.usp.br:article/26762Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:43:02.443979Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false
dc.title.none.fl_str_mv Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits
Alterações reprodutivas em ratos machos expostos perinatalmente aos frutos da Solanum lycocarpum
title Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits
spellingShingle Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits
Schwarz, Aline
Solanum lycocarpum
Solasodina
Função reprodutiva
Fertilidade
Produção espermática
Rato
Solanum lycocarpum
Solasodine
Reproductive function
Fertility
Sperm production
Rat
title_short Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits
title_full Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits
title_fullStr Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits
title_full_unstemmed Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits
title_sort Reproductive alterations in male rats exposed perinatally to Solanum lycocarpum fruits
author Schwarz, Aline
author_facet Schwarz, Aline
Kempinas, Wilma De Grava
Soares, Milena Rodrigues
Bernardi, Maria Martha
Spinosa, Helenice de Souza
author_role author
author2 Kempinas, Wilma De Grava
Soares, Milena Rodrigues
Bernardi, Maria Martha
Spinosa, Helenice de Souza
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Schwarz, Aline
Kempinas, Wilma De Grava
Soares, Milena Rodrigues
Bernardi, Maria Martha
Spinosa, Helenice de Souza
dc.subject.por.fl_str_mv Solanum lycocarpum
Solasodina
Função reprodutiva
Fertilidade
Produção espermática
Rato
Solanum lycocarpum
Solasodine
Reproductive function
Fertility
Sperm production
Rat
topic Solanum lycocarpum
Solasodina
Função reprodutiva
Fertilidade
Produção espermática
Rato
Solanum lycocarpum
Solasodine
Reproductive function
Fertility
Sperm production
Rat
description This work employed pregnant rats treated with Solanum lycocarpum unripe fruits (10% in diet) from gestation day (GD) 06 to post-natal day (PND) 07, for the evaluation of the sperm number, daily sperm production and epididymal sperm transit time of the male offspring at PND 60 and PND 90. No differences were observed in the daily sperm production (DSP) and sperm number in the testis of the exposed males at PND 60 and PND 90. Also, no alterations were observed in sperm transit time in the caput epididymis of the exposed males at PND 60 and PND 90. However, a reduced sperm transit time was observed in the corpus/cauda epididymis of the experimental males at PND 90. The last data may explain the reduced sperm number observed in the corpus/cauda epididymis of the experimental male rats at PND 90. These data show that the male rats exposed to S. lycocarpum fruits during gestation did not present alterations in testis sperm production and number, however the sperm transit time through epididymis was impaired, resulting in a decreased number of spermatozoa in epididymis cauda. We conclude that S. lycocarpum may cause imbalance on hypothalamus-pituitary gland axis
publishDate 2009
dc.date.none.fl_str_mv 2009-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/26762
10.11606/issn.1678-4456.bjvras.2009.26762
url https://www.revistas.usp.br/bjvras/article/view/26762
identifier_str_mv 10.11606/issn.1678-4456.bjvras.2009.26762
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/26762/28545
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science; Vol. 46 Núm. 2 (2009); 152-157
Brazilian Journal of Veterinary Research and Animal Science; Vol. 46 No. 2 (2009); 152-157
Brazilian Journal of Veterinary Research and Animal Science; v. 46 n. 2 (2009); 152-157
Brazilian Journal of Veterinary Research and Animal Science; V. 46 N. 2 (2009); 152-157
1678-4456
1413-9596
reponame:Brazilian Journal of Veterinary Research and Animal Science
instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron:USP
instname_str Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Veterinary Research and Animal Science
collection Brazilian Journal of Veterinary Research and Animal Science
repository.name.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
repository.mail.fl_str_mv bjvras@usp.br
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