Effect of charcoal-treated bovine follicular fluid on the secretion of FSH in ovariectomized and intact prepubertal heifers

• Autor(a) principal: Alvarez, Rafael Herrera
• Data de Publicação: 1998
• Outros Autores: Arcaro, Juliana Rodrigues Pozzi, Ribela, Maria Teresa Carvalho Pinto, Perone, Cibele Nunes
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
• Texto Completo: https://www.revistas.usp.br/bjvras/article/view/5685
• topic: Fluido folicular; FSH; Bovinos; Follicular fluid; FSH; Bovine

The aim of the experiment was to determine whether charcoal-treated bovine follicular fluid (bFF) removed from visible (< 22 mm) follicles altered the secretion of follicle-stimulating hormone (FSH) in intact and ovariectomized prepubertal heifers. After a 10-ml injection of bFF given at three consecutive 8-h intervals, secretion of FSH was depressed in approximately 44% of the ovariectomized heifers but there was no effect in intact heifers. When the bFF treatment ceased, there were no rebound effects on FSH concentrations above that of controls pretreatment levels. These results suggest that proteins from bFF act at the pituitary level to inhibit FSH secretion and, differently of the intact, the ovariectomized heifer is an adequate model to put this effect in evidence, particularly when the bFF have low FSH suppressing activity.