Genetic characterization of bovine viral diarrhoea virus detected in persistently infected cattle in Southern Minas Gerais, Brazil

• Autor(a) principal: Dias, Fabio Carvalho
• Data de Publicação: 2012
• Outros Autores: Médici, Kerlei Cristina, Sousa, Ricardo Luiz Moro de, Alfieri, Amauri Alcindo, Samara, Samir Issa
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
• Texto Completo: https://www.revistas.usp.br/bjvras/article/view/53921
• topic: Vírus da diarreia viral bovina; Animal persistentemente infectado; Caracterização genotípica; Brasil; Bovine viral diarrhoea virus; Persistently infected animal; Genotypic characterization; Brazil

Isolates of bovine viral diarrhoea virus (BVDV) detected in serum samples of two persistently infected animals (PI) identified in a herd located in the southern state of Minas Gerais, Brazil, underwent genetic characterization trough partial nucleotide sequencing and analysis of the 5’ Untranslated Region (5’UTR) of the viral genome. The isolates were characterized as belonging to genotype BVDV-1, subgenotype BVDV-1b. The results of this study suggest BVDV-1b as an agent of importance in the occurrence of bovine viral diarrhoea (BVD) in the herds of the region. Moreover, the genotypic characterization of isolates of BVDV helps to better understand the epidemiology of the disease, as the genetic variability of BVDV interferes in the serological tests and has implications for the use of vaccines, whose majority is produced only with reference strains of BVDV. Therefore, the investigation on the genetic diversity of BVDV existing in Brazil is required for the improvement of the disease prevention and control measures