Fine needle aspiration cytologic and histologic correlation in canine mammary tumors

Detalhes bibliográficos
Autor(a) principal: Zuccari, Debora Aparecida Pires de Campos
Data de Publicação: 2001
Outros Autores: Santana, Aureo Evangelista, Rocha, Noeme Souza
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
Texto Completo: https://www.revistas.usp.br/bjvras/article/view/5917
Resumo: Cytologic and histologic examination of 35 canine mammary masses was performed over a year period, from dogs that underwent mastectomy for mammary neoplasms at the UNESP Veterinary Medical Teaching Hospital -- Jaboticabal (SP) Brazil. The mastectomy specimens were evaluated according to structural parameters found to be prognostically significant in human mammary tumors, such as grade of atypia, nuclear criteria (shape, size, form, abnormal mitotic figures), chromatin and nucleolar patterns, high cellularity and poor intercellular cohesions. These criteria were used for differentiation of benign from malignant mammary tumors with 63% of a concordant diagnosis and sensibility of 73% and specificity of 83%. The "fine needle aspiration" technique is discussed as a tool to perform early diagnosis. Our data were found to have a positive correlation to the prognosis indicating that we can recognize structural variables of malignancy by citopathology. Application of the described parameters should facilitate comparative studies of histopathologic diagnosis with biologic behavior of canine mammary tumors using this technique to obtain early diagnosis and a secure prognosis.
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spelling Fine needle aspiration cytologic and histologic correlation in canine mammary tumorsCorrelação entre a citologia aspirativa por agulha fina e a histologia no diagnóstico de tumores mamários de cadelasNeoplasias das glândulas mamáriasCadelasHistopatologiaCitologia Aspirativa por Agulha FinaMammary gland neoplasmsBitchHistopathologyFine Needle AspirationCytologic and histologic examination of 35 canine mammary masses was performed over a year period, from dogs that underwent mastectomy for mammary neoplasms at the UNESP Veterinary Medical Teaching Hospital -- Jaboticabal (SP) Brazil. The mastectomy specimens were evaluated according to structural parameters found to be prognostically significant in human mammary tumors, such as grade of atypia, nuclear criteria (shape, size, form, abnormal mitotic figures), chromatin and nucleolar patterns, high cellularity and poor intercellular cohesions. These criteria were used for differentiation of benign from malignant mammary tumors with 63% of a concordant diagnosis and sensibility of 73% and specificity of 83%. The "fine needle aspiration" technique is discussed as a tool to perform early diagnosis. Our data were found to have a positive correlation to the prognosis indicating that we can recognize structural variables of malignancy by citopathology. Application of the described parameters should facilitate comparative studies of histopathologic diagnosis with biologic behavior of canine mammary tumors using this technique to obtain early diagnosis and a secure prognosis.Foram estudados tumores de mama em cadelas, comparando o seu padrão citológico, obtido através da Citologia Aspirativa por Agulha Fina (CAAF), com os resultados da histopatologia. Num período de um ano, as cadelas trazidas ao Hospital Veterinário -- UNESP -- Câmpus de Jaboticabal foram submetidas a exérese cirúrgica dos tumores mamários. As amostras foram avaliadas de acordo com parâmetros estruturais utilizados nos tumores mamários humanos, como grau de atipia, critérios nucleares, padrão de cromatina e nucléolos, alta celularidade e pouca coesão intercelular. Utilizaram-se estes critérios para diferenciar tumores mamários benignos de malignos com 63% de diagnósticos concordantes, sensibilidade de 73% e especificidade de 83%. Nossos dados mostraram ter uma correlação positiva com o prognóstico, demonstrando que é possível reconhecer variáveis estruturais de malignidade na citopatologia para obter um diagnóstico precoce e um prognóstico seguro.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2001-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/591710.1590/S1413-95962001000100007Brazilian Journal of Veterinary Research and Animal Science; Vol. 38 Núm. 1 (2001); 38-41Brazilian Journal of Veterinary Research and Animal Science; Vol. 38 No. 1 (2001); 38-41Brazilian Journal of Veterinary Research and Animal Science; v. 38 n. 1 (2001); 38-41Brazilian Journal of Veterinary Research and Animal Science; V. 38 N. 1 (2001); 38-411678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/5917/7448Zuccari, Debora Aparecida Pires de CamposSantana, Aureo EvangelistaRocha, Noeme Souzainfo:eu-repo/semantics/openAccess2020-06-23T04:38:33Zoai:revistas.usp.br:article/5917Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:42:29.361371Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false
dc.title.none.fl_str_mv Fine needle aspiration cytologic and histologic correlation in canine mammary tumors
Correlação entre a citologia aspirativa por agulha fina e a histologia no diagnóstico de tumores mamários de cadelas
title Fine needle aspiration cytologic and histologic correlation in canine mammary tumors
spellingShingle Fine needle aspiration cytologic and histologic correlation in canine mammary tumors
Zuccari, Debora Aparecida Pires de Campos
Neoplasias das glândulas mamárias
Cadelas
Histopatologia
Citologia Aspirativa por Agulha Fina
Mammary gland neoplasms
Bitch
Histopathology
Fine Needle Aspiration
title_short Fine needle aspiration cytologic and histologic correlation in canine mammary tumors
title_full Fine needle aspiration cytologic and histologic correlation in canine mammary tumors
title_fullStr Fine needle aspiration cytologic and histologic correlation in canine mammary tumors
title_full_unstemmed Fine needle aspiration cytologic and histologic correlation in canine mammary tumors
title_sort Fine needle aspiration cytologic and histologic correlation in canine mammary tumors
author Zuccari, Debora Aparecida Pires de Campos
author_facet Zuccari, Debora Aparecida Pires de Campos
Santana, Aureo Evangelista
Rocha, Noeme Souza
author_role author
author2 Santana, Aureo Evangelista
Rocha, Noeme Souza
author2_role author
author
dc.contributor.author.fl_str_mv Zuccari, Debora Aparecida Pires de Campos
Santana, Aureo Evangelista
Rocha, Noeme Souza
dc.subject.por.fl_str_mv Neoplasias das glândulas mamárias
Cadelas
Histopatologia
Citologia Aspirativa por Agulha Fina
Mammary gland neoplasms
Bitch
Histopathology
Fine Needle Aspiration
topic Neoplasias das glândulas mamárias
Cadelas
Histopatologia
Citologia Aspirativa por Agulha Fina
Mammary gland neoplasms
Bitch
Histopathology
Fine Needle Aspiration
description Cytologic and histologic examination of 35 canine mammary masses was performed over a year period, from dogs that underwent mastectomy for mammary neoplasms at the UNESP Veterinary Medical Teaching Hospital -- Jaboticabal (SP) Brazil. The mastectomy specimens were evaluated according to structural parameters found to be prognostically significant in human mammary tumors, such as grade of atypia, nuclear criteria (shape, size, form, abnormal mitotic figures), chromatin and nucleolar patterns, high cellularity and poor intercellular cohesions. These criteria were used for differentiation of benign from malignant mammary tumors with 63% of a concordant diagnosis and sensibility of 73% and specificity of 83%. The "fine needle aspiration" technique is discussed as a tool to perform early diagnosis. Our data were found to have a positive correlation to the prognosis indicating that we can recognize structural variables of malignancy by citopathology. Application of the described parameters should facilitate comparative studies of histopathologic diagnosis with biologic behavior of canine mammary tumors using this technique to obtain early diagnosis and a secure prognosis.
publishDate 2001
dc.date.none.fl_str_mv 2001-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/5917
10.1590/S1413-95962001000100007
url https://www.revistas.usp.br/bjvras/article/view/5917
identifier_str_mv 10.1590/S1413-95962001000100007
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/5917/7448
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science; Vol. 38 Núm. 1 (2001); 38-41
Brazilian Journal of Veterinary Research and Animal Science; Vol. 38 No. 1 (2001); 38-41
Brazilian Journal of Veterinary Research and Animal Science; v. 38 n. 1 (2001); 38-41
Brazilian Journal of Veterinary Research and Animal Science; V. 38 N. 1 (2001); 38-41
1678-4456
1413-9596
reponame:Brazilian Journal of Veterinary Research and Animal Science
instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron:USP
instname_str Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Veterinary Research and Animal Science
collection Brazilian Journal of Veterinary Research and Animal Science
repository.name.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
repository.mail.fl_str_mv bjvras@usp.br
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