Experimental peritonitis in horses. Hematological and biochemistry aspects

• Autor(a) principal: Mendes, Luiz Cláudio Nogueira
• Data de Publicação: 2000
• Outros Autores: Marques, Luiz Carlos, Schocken-Iturrino, Ruben Pablo, Ávila, Fernando Antônio de, Malheiros, Euclides Braga
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
• Texto Completo: https://www.revistas.usp.br/bjvras/article/view/5836
• topic: Peritonite; Eqüinos; Escherichia coli; Bacteroides fragilis; Peritonitis; Horses; Escherichia coli; Bacteroides fragilis

Sixteen adult horses were randomly divided into 4 equal groups (GI, GII, GIII and GIV) of 4 animals and each group was injected intraperitoneally with one of the following suspension: Group I, 100 x 10(7) colony-forming units (CFU) of E. coli diluted in 500 ml of 0.9% saline; Group II, 100 x 10(7) CFU of Bacteroides fragilis in 500 ml of 0.9% saline; Group III, 100 x 10(7) CFU of E. coli in combination with 100 x 10(7) CFU of B. fragilis in 500 ml of 0.9% saline; Group IV, 500 ml of 0.9% saline. Leukopenia appeared in all animals inoculated with bacteria within the first six hours of the experiment. After this period, leukocytosis was observed in some inoculated horses. Horses inoculated with pure cultures of either E. coli or B. fragilis demonstrated mild and self-limiting peritonitis, whereas those inoculated with a combination of both bacteria demonstrated laboratory findings of higher intensity and duration.