Neuromuscular blockade in children

Detalhes bibliográficos
Autor(a) principal: Almeida,João Fernando Lourenço de
Data de Publicação: 2000
Outros Autores: Kalil Filho,W. Jorge, Troster,Eduardo J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Hospital das Clínicas
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812000000300007
Resumo: Neuromuscular blocking agents (NMBAs) have been widely used to control patients who need to be immobilized for some kind of medical intervention, such as an invasive procedure or synchronism with mechanical ventilation. The purpose of this monograph is to review the pharmacology of the NMBAs, to compare the main differences between the neuromuscular junction in neonates, infants, toddlers and adults, and moreover to discuss their indications in critically ill pediatric patients. Continuous improvement of knowledge about NMBAs pharmacology, adverse effects, and the many other remaining unanswered questions about neuromuscular junction and neuromuscular blockade in children is essential for the correct use of these drugs. Therefore, the indication of these agents in pediatrics is determined with extreme judiciousness. Computorized (Medline 1990-2000) and active search of articles were the mechanisms used in this review.
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spelling Neuromuscular blockade in childrenNeuromuscular blocking agentsNeuromuscular blocking drugsNeuromuscular junctionNeuromuscular blockNeonateInfantChildNeuromuscular blocking agents (NMBAs) have been widely used to control patients who need to be immobilized for some kind of medical intervention, such as an invasive procedure or synchronism with mechanical ventilation. The purpose of this monograph is to review the pharmacology of the NMBAs, to compare the main differences between the neuromuscular junction in neonates, infants, toddlers and adults, and moreover to discuss their indications in critically ill pediatric patients. Continuous improvement of knowledge about NMBAs pharmacology, adverse effects, and the many other remaining unanswered questions about neuromuscular junction and neuromuscular blockade in children is essential for the correct use of these drugs. Therefore, the indication of these agents in pediatrics is determined with extreme judiciousness. Computorized (Medline 1990-2000) and active search of articles were the mechanisms used in this review.Faculdade de Medicina / Universidade de São Paulo - FM/USP2000-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812000000300007Revista do Hospital das Clínicas v.55 n.3 2000reponame:Revista do Hospital das Clínicasinstname:Universidade de São Paulo (USP)instacron:USP10.1590/S0041-87812000000300007info:eu-repo/semantics/openAccessAlmeida,João Fernando Lourenço deKalil Filho,W. JorgeTroster,Eduardo J.eng2000-09-06T00:00:00Zoai:scielo:S0041-87812000000300007Revistahttp://www.scielo.br/rhcPUBhttps://old.scielo.br/oai/scielo-oai.php||revista.hc@hcnet.usp.br1678-99030041-8781opendoar:2000-09-06T00:00Revista do Hospital das Clínicas - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Neuromuscular blockade in children
title Neuromuscular blockade in children
spellingShingle Neuromuscular blockade in children
Almeida,João Fernando Lourenço de
Neuromuscular blocking agents
Neuromuscular blocking drugs
Neuromuscular junction
Neuromuscular block
Neonate
Infant
Child
title_short Neuromuscular blockade in children
title_full Neuromuscular blockade in children
title_fullStr Neuromuscular blockade in children
title_full_unstemmed Neuromuscular blockade in children
title_sort Neuromuscular blockade in children
author Almeida,João Fernando Lourenço de
author_facet Almeida,João Fernando Lourenço de
Kalil Filho,W. Jorge
Troster,Eduardo J.
author_role author
author2 Kalil Filho,W. Jorge
Troster,Eduardo J.
author2_role author
author
dc.contributor.author.fl_str_mv Almeida,João Fernando Lourenço de
Kalil Filho,W. Jorge
Troster,Eduardo J.
dc.subject.por.fl_str_mv Neuromuscular blocking agents
Neuromuscular blocking drugs
Neuromuscular junction
Neuromuscular block
Neonate
Infant
Child
topic Neuromuscular blocking agents
Neuromuscular blocking drugs
Neuromuscular junction
Neuromuscular block
Neonate
Infant
Child
description Neuromuscular blocking agents (NMBAs) have been widely used to control patients who need to be immobilized for some kind of medical intervention, such as an invasive procedure or synchronism with mechanical ventilation. The purpose of this monograph is to review the pharmacology of the NMBAs, to compare the main differences between the neuromuscular junction in neonates, infants, toddlers and adults, and moreover to discuss their indications in critically ill pediatric patients. Continuous improvement of knowledge about NMBAs pharmacology, adverse effects, and the many other remaining unanswered questions about neuromuscular junction and neuromuscular blockade in children is essential for the correct use of these drugs. Therefore, the indication of these agents in pediatrics is determined with extreme judiciousness. Computorized (Medline 1990-2000) and active search of articles were the mechanisms used in this review.
publishDate 2000
dc.date.none.fl_str_mv 2000-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812000000300007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812000000300007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0041-87812000000300007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade de Medicina / Universidade de São Paulo - FM/USP
publisher.none.fl_str_mv Faculdade de Medicina / Universidade de São Paulo - FM/USP
dc.source.none.fl_str_mv Revista do Hospital das Clínicas v.55 n.3 2000
reponame:Revista do Hospital das Clínicas
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista do Hospital das Clínicas
collection Revista do Hospital das Clínicas
repository.name.fl_str_mv Revista do Hospital das Clínicas - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||revista.hc@hcnet.usp.br
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