Pouchitis: extracolonic manifestation of ulcerative colitis?

Detalhes bibliográficos
Autor(a) principal: Teixeira,William Gemio Jacobsen
Data de Publicação: 1999
Outros Autores: Silva,José Hyppólito da, Teixeira,Magaly Gemio, Almeida,Maristela, Calache,João Elias, Habr-Gama,Angelita
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Hospital das Clínicas
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87811999000500005
Resumo: Pouchitis is the most frequent complication of ileal pouch-anal anastomosis for treatment of ulcerative colitis. There are several possible explanations. Among them, we focus on the one that considers pouchitis as an extracolonic manifestation of ulcerative colitis. The aim of this study was to investigate the association between pouchitis and extra-intestinal manifestations (EIM), which are frequent in these patients. Sixty patients underwent restorative proctocolectomy with an ileal J pouch (IPAA) from September 1984 to December 1998. Pouchitis was defined by clinical, endoscopic, and histologic criteria. The following extra-intestinal manifestations were studied: articular, cutaneous, hepatobiliary, ocular, genitourinary, and growth failure. Thirteen patients, of which 10 were female (76.9%), developed one or more episodes of pouchitis. Twelve patients of this group (92.3%) presented some kind of extra-intestinal manifestation, 4 pre-operatively (exclusively), 2 post-operatively (exclusively), and 6 both pre- and post-operatively (1.7 per patient). Twenty patients (42.7%) of the 47 without pouchitis did not present extra-intestinal manifestations; 10/35 (28.5%) of females had pouchitis, compared to 3/35 (12.0%) of men. Pouchitis was more frequent among females, though not statistically significant. EIM increases the risk of pouchitis. Pouchitis is related to EIM in 92.3 % of cases, corroborating the hypothesis that it could be an extracolonic manifestation of ulcerative colitis.
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spelling Pouchitis: extracolonic manifestation of ulcerative colitis?Ulcerative colitisIleal-pouch anastomosisExtraintestinal manifestationsPouchitis surgerPouchitis is the most frequent complication of ileal pouch-anal anastomosis for treatment of ulcerative colitis. There are several possible explanations. Among them, we focus on the one that considers pouchitis as an extracolonic manifestation of ulcerative colitis. The aim of this study was to investigate the association between pouchitis and extra-intestinal manifestations (EIM), which are frequent in these patients. Sixty patients underwent restorative proctocolectomy with an ileal J pouch (IPAA) from September 1984 to December 1998. Pouchitis was defined by clinical, endoscopic, and histologic criteria. The following extra-intestinal manifestations were studied: articular, cutaneous, hepatobiliary, ocular, genitourinary, and growth failure. Thirteen patients, of which 10 were female (76.9%), developed one or more episodes of pouchitis. Twelve patients of this group (92.3%) presented some kind of extra-intestinal manifestation, 4 pre-operatively (exclusively), 2 post-operatively (exclusively), and 6 both pre- and post-operatively (1.7 per patient). Twenty patients (42.7%) of the 47 without pouchitis did not present extra-intestinal manifestations; 10/35 (28.5%) of females had pouchitis, compared to 3/35 (12.0%) of men. Pouchitis was more frequent among females, though not statistically significant. EIM increases the risk of pouchitis. Pouchitis is related to EIM in 92.3 % of cases, corroborating the hypothesis that it could be an extracolonic manifestation of ulcerative colitis.Faculdade de Medicina / Universidade de São Paulo - FM/USP1999-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87811999000500005Revista do Hospital das Clínicas v.54 n.5 1999reponame:Revista do Hospital das Clínicasinstname:Universidade de São Paulo (USP)instacron:USP10.1590/S0041-87811999000500005info:eu-repo/semantics/openAccessTeixeira,William Gemio JacobsenSilva,José Hyppólito daTeixeira,Magaly GemioAlmeida,MaristelaCalache,João EliasHabr-Gama,Angelitaeng2000-04-28T00:00:00Zoai:scielo:S0041-87811999000500005Revistahttp://www.scielo.br/rhcPUBhttps://old.scielo.br/oai/scielo-oai.php||revista.hc@hcnet.usp.br1678-99030041-8781opendoar:2000-04-28T00:00Revista do Hospital das Clínicas - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Pouchitis: extracolonic manifestation of ulcerative colitis?
title Pouchitis: extracolonic manifestation of ulcerative colitis?
spellingShingle Pouchitis: extracolonic manifestation of ulcerative colitis?
Teixeira,William Gemio Jacobsen
Ulcerative colitis
Ileal-pouch anastomosis
Extraintestinal manifestations
Pouchitis surger
title_short Pouchitis: extracolonic manifestation of ulcerative colitis?
title_full Pouchitis: extracolonic manifestation of ulcerative colitis?
title_fullStr Pouchitis: extracolonic manifestation of ulcerative colitis?
title_full_unstemmed Pouchitis: extracolonic manifestation of ulcerative colitis?
title_sort Pouchitis: extracolonic manifestation of ulcerative colitis?
author Teixeira,William Gemio Jacobsen
author_facet Teixeira,William Gemio Jacobsen
Silva,José Hyppólito da
Teixeira,Magaly Gemio
Almeida,Maristela
Calache,João Elias
Habr-Gama,Angelita
author_role author
author2 Silva,José Hyppólito da
Teixeira,Magaly Gemio
Almeida,Maristela
Calache,João Elias
Habr-Gama,Angelita
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Teixeira,William Gemio Jacobsen
Silva,José Hyppólito da
Teixeira,Magaly Gemio
Almeida,Maristela
Calache,João Elias
Habr-Gama,Angelita
dc.subject.por.fl_str_mv Ulcerative colitis
Ileal-pouch anastomosis
Extraintestinal manifestations
Pouchitis surger
topic Ulcerative colitis
Ileal-pouch anastomosis
Extraintestinal manifestations
Pouchitis surger
description Pouchitis is the most frequent complication of ileal pouch-anal anastomosis for treatment of ulcerative colitis. There are several possible explanations. Among them, we focus on the one that considers pouchitis as an extracolonic manifestation of ulcerative colitis. The aim of this study was to investigate the association between pouchitis and extra-intestinal manifestations (EIM), which are frequent in these patients. Sixty patients underwent restorative proctocolectomy with an ileal J pouch (IPAA) from September 1984 to December 1998. Pouchitis was defined by clinical, endoscopic, and histologic criteria. The following extra-intestinal manifestations were studied: articular, cutaneous, hepatobiliary, ocular, genitourinary, and growth failure. Thirteen patients, of which 10 were female (76.9%), developed one or more episodes of pouchitis. Twelve patients of this group (92.3%) presented some kind of extra-intestinal manifestation, 4 pre-operatively (exclusively), 2 post-operatively (exclusively), and 6 both pre- and post-operatively (1.7 per patient). Twenty patients (42.7%) of the 47 without pouchitis did not present extra-intestinal manifestations; 10/35 (28.5%) of females had pouchitis, compared to 3/35 (12.0%) of men. Pouchitis was more frequent among females, though not statistically significant. EIM increases the risk of pouchitis. Pouchitis is related to EIM in 92.3 % of cases, corroborating the hypothesis that it could be an extracolonic manifestation of ulcerative colitis.
publishDate 1999
dc.date.none.fl_str_mv 1999-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87811999000500005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87811999000500005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0041-87811999000500005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade de Medicina / Universidade de São Paulo - FM/USP
publisher.none.fl_str_mv Faculdade de Medicina / Universidade de São Paulo - FM/USP
dc.source.none.fl_str_mv Revista do Hospital das Clínicas v.54 n.5 1999
reponame:Revista do Hospital das Clínicas
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista do Hospital das Clínicas
collection Revista do Hospital das Clínicas
repository.name.fl_str_mv Revista do Hospital das Clínicas - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||revista.hc@hcnet.usp.br
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