Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes?
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Archives of Clinical Psychiatry |
Texto Completo: | https://www.revistas.usp.br/acp/article/view/153014 |
Resumo: | Background: Optical coherence tomography is a contactless and fast neuroimaging method. Previous Studies have observed thinning of the ganglion cell layer and inner plexiform layer in many neurodegenerative diseases. Objective: The aim of this study was to compare the layers of ganglion cell complex in conversion disorder. Methods: This study involved 50 conversion disorder patients and 50 healthy volunteers as the control. The parameters were measured and recorded automatically by a spectral optical coherence tomography device. Results: There was no difference in the retinal nerve fiber layers between the conversion disorder group and the control group (p > 0.05). The left and right choroid layer thickness acquired from three regions of the choroid layer was higher in patients compared with controls (p < 0.05). The ganglion cell layer and inner plexiform layer volumes were also significantly lower in the patient group (p < 0.05). Discussion: These ganglion cell layer and inner plexiform layer findings suggest that neurodegeneration occurs during the course of conversion disorder especially in subtype involved motor component. The choroid seems to be more related to the sensory component and it may be used to determine the active stage of the disease and to monitor inflammatory process like other inflammation markers used in systemic inflammatory diseases. |
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Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes?Conversion disorderganglion cell layerinner plexiform layerneuron degenerationoptical coherence tomographyBackground: Optical coherence tomography is a contactless and fast neuroimaging method. Previous Studies have observed thinning of the ganglion cell layer and inner plexiform layer in many neurodegenerative diseases. Objective: The aim of this study was to compare the layers of ganglion cell complex in conversion disorder. Methods: This study involved 50 conversion disorder patients and 50 healthy volunteers as the control. The parameters were measured and recorded automatically by a spectral optical coherence tomography device. Results: There was no difference in the retinal nerve fiber layers between the conversion disorder group and the control group (p > 0.05). The left and right choroid layer thickness acquired from three regions of the choroid layer was higher in patients compared with controls (p < 0.05). The ganglion cell layer and inner plexiform layer volumes were also significantly lower in the patient group (p < 0.05). Discussion: These ganglion cell layer and inner plexiform layer findings suggest that neurodegeneration occurs during the course of conversion disorder especially in subtype involved motor component. The choroid seems to be more related to the sensory component and it may be used to determine the active stage of the disease and to monitor inflammatory process like other inflammation markers used in systemic inflammatory diseases.Universidade de São Paulo. Faculdade de Medicina. Instituto de Psiquiatria2018-12-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/acp/article/view/15301410.1590/acp.v45i6.153014Archives of Clinical Psychiatry; v. 45 n. 6 (2018); 154-160Archives of Clinical Psychiatry; Vol. 45 No. 6 (2018); 154-160Revista de Psiquiatria Clínica; Vol. 45 Núm. 6 (2018); 154-1601806-938X0101-6083reponame:Archives of Clinical Psychiatryinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/acp/article/view/153014/149513Copyright (c) 2018 Archives of Clinical Psychiatryinfo:eu-repo/semantics/openAccessKaradag, Ayse SevgiKalenderoglu, AysunOrum, Mehmet Hamdi2018-12-19T18:37:36Zoai:revistas.usp.br:article/153014Revistahttp://www.hcnet.usp.br/ipq/revista/index.htmlPUBhttps://old.scielo.br/oai/scielo-oai.php||archives@usp.br1806-938X0101-6083opendoar:2018-12-19T18:37:36Archives of Clinical Psychiatry - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes? |
title |
Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes? |
spellingShingle |
Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes? Karadag, Ayse Sevgi Conversion disorder ganglion cell layer inner plexiform layer neuron degeneration optical coherence tomography |
title_short |
Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes? |
title_full |
Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes? |
title_fullStr |
Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes? |
title_full_unstemmed |
Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes? |
title_sort |
Optical coherence tomography findings in conversion disorder: are there any differences in the etiopathogenesis of subtypes? |
author |
Karadag, Ayse Sevgi |
author_facet |
Karadag, Ayse Sevgi Kalenderoglu, Aysun Orum, Mehmet Hamdi |
author_role |
author |
author2 |
Kalenderoglu, Aysun Orum, Mehmet Hamdi |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Karadag, Ayse Sevgi Kalenderoglu, Aysun Orum, Mehmet Hamdi |
dc.subject.por.fl_str_mv |
Conversion disorder ganglion cell layer inner plexiform layer neuron degeneration optical coherence tomography |
topic |
Conversion disorder ganglion cell layer inner plexiform layer neuron degeneration optical coherence tomography |
description |
Background: Optical coherence tomography is a contactless and fast neuroimaging method. Previous Studies have observed thinning of the ganglion cell layer and inner plexiform layer in many neurodegenerative diseases. Objective: The aim of this study was to compare the layers of ganglion cell complex in conversion disorder. Methods: This study involved 50 conversion disorder patients and 50 healthy volunteers as the control. The parameters were measured and recorded automatically by a spectral optical coherence tomography device. Results: There was no difference in the retinal nerve fiber layers between the conversion disorder group and the control group (p > 0.05). The left and right choroid layer thickness acquired from three regions of the choroid layer was higher in patients compared with controls (p < 0.05). The ganglion cell layer and inner plexiform layer volumes were also significantly lower in the patient group (p < 0.05). Discussion: These ganglion cell layer and inner plexiform layer findings suggest that neurodegeneration occurs during the course of conversion disorder especially in subtype involved motor component. The choroid seems to be more related to the sensory component and it may be used to determine the active stage of the disease and to monitor inflammatory process like other inflammation markers used in systemic inflammatory diseases. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/acp/article/view/153014 10.1590/acp.v45i6.153014 |
url |
https://www.revistas.usp.br/acp/article/view/153014 |
identifier_str_mv |
10.1590/acp.v45i6.153014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/acp/article/view/153014/149513 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Archives of Clinical Psychiatry info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Archives of Clinical Psychiatry |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina. Instituto de Psiquiatria |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina. Instituto de Psiquiatria |
dc.source.none.fl_str_mv |
Archives of Clinical Psychiatry; v. 45 n. 6 (2018); 154-160 Archives of Clinical Psychiatry; Vol. 45 No. 6 (2018); 154-160 Revista de Psiquiatria Clínica; Vol. 45 Núm. 6 (2018); 154-160 1806-938X 0101-6083 reponame:Archives of Clinical Psychiatry instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Archives of Clinical Psychiatry |
collection |
Archives of Clinical Psychiatry |
repository.name.fl_str_mv |
Archives of Clinical Psychiatry - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||archives@usp.br |
_version_ |
1800237624263180288 |