Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Fisioterapia e Pesquisa |
Texto Completo: | https://www.revistas.usp.br/fpusp/article/view/77289 |
Resumo: | With the population aging, the prevalence of chronic diseases of muscles and joints restricting in the elderly functional capacity has been increasing. The rheumatoid arthritis is part of this group of pathologies and the treatment of the disease has been basically to reduce the symptoms as pain, edema, rigidity, muscular atrophies through the inhibition of the inflammatory process. For this, treatments with drugs and treatment with physical therapeutics resources are used. The ultrasound is a physical therapeutic resource that has been used thoroughly in the clinical practice with the objective of solving the inflammatory process of the rheumatoid arthritis. The effect of the ultra-sound was observed on the edema and on the hyperalgesia of the posterior paws of arthritic rats. The rheumatoid arthritis was induced through an injection of an emulsion oil-water contends 400 ?g of Micobacierium butiricum. The hyperalgesia was detected in the 11 st day and the edema in the 12nd day after the induction of the rheumatoid arthritis. For comparative study, it was administered the indometacina orally in the dose of 0,5 mg/kg/dia during 15 days where we didn't observe reduction of the hyperalgesia but there was reduction of the edema of the posterior paws of the arthritic rats. The ultrasound in the frequency of 1 MHz. intensity 0,2 watts/cm2, for 5 minutes, for 15 days didn't reduce the hyperalgesia or edema of the posterior paws of the arthritic rats. The association of the ultrasound with the indomethacin in the doses already mentioned previously got to inhibit the hyperalgesia and edema of the posterior paws of the arthritic rats significantly. |
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Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic ratsOs efeitos do ultra-som na hyperalgesia e no edema de ratos artríticosTerapia por ultrassommétodosEnvelhecimentoFisioterapiareabilitaçãoHiperalgesiaArtriteEdemasUltrasonic therapymethodsAgingPhysical therapyreabilitaçãoHyperalgesiaArthritis rheumatoidrehabilitationEdemaWith the population aging, the prevalence of chronic diseases of muscles and joints restricting in the elderly functional capacity has been increasing. The rheumatoid arthritis is part of this group of pathologies and the treatment of the disease has been basically to reduce the symptoms as pain, edema, rigidity, muscular atrophies through the inhibition of the inflammatory process. For this, treatments with drugs and treatment with physical therapeutics resources are used. The ultrasound is a physical therapeutic resource that has been used thoroughly in the clinical practice with the objective of solving the inflammatory process of the rheumatoid arthritis. The effect of the ultra-sound was observed on the edema and on the hyperalgesia of the posterior paws of arthritic rats. The rheumatoid arthritis was induced through an injection of an emulsion oil-water contends 400 ?g of Micobacierium butiricum. The hyperalgesia was detected in the 11 st day and the edema in the 12nd day after the induction of the rheumatoid arthritis. For comparative study, it was administered the indometacina orally in the dose of 0,5 mg/kg/dia during 15 days where we didn't observe reduction of the hyperalgesia but there was reduction of the edema of the posterior paws of the arthritic rats. The ultrasound in the frequency of 1 MHz. intensity 0,2 watts/cm2, for 5 minutes, for 15 days didn't reduce the hyperalgesia or edema of the posterior paws of the arthritic rats. The association of the ultrasound with the indomethacin in the doses already mentioned previously got to inhibit the hyperalgesia and edema of the posterior paws of the arthritic rats significantly.Com o envelhecimento populacional a prevalência de doenças osteomusculares crônicas, que restringem a capacidade funcional dos idosos tem aumentado. A artrite reumatóide, integrante desse grupo de patologias, tem atualmente a sua abordagem terapêutica realizada através dô medicamentos e de fisioterapia. Os tratamentos propostos consistem basicamente em reduzir os sintomas apresentados pela doença tais como: a dor, o edema, a rigidez e a atrofia muscular, através da inibição do processo inflamatórip. Foi observado o efeito do ultra-som no edema e na hiperalgesia das patas posteriores de ratos artríticos. A artrite reumatóide foi induzida experimentalmente através de uma injeção de uma emulsão óleo-água contendo 400 ug de Micobacterium butiricum. A hiperalgesia foi detectada no 1 I o dia e o edema no 12° dia após a indução da artrite. O ultra-som com uma freqüência de 1 MHz, intensidade de 0,2 watts/cm2 , aplicado por 5 minutos diariamente durante 15 dias, não reduziu a hiperalgesia ou p edema das patas posteriores dos ratos artríticos. Para estudo comparativo, foi administrado um antiinflamatório não-esteróide, a indometacina, por via oral na dose de 0,5 mg/kg/dia durante 15 dias consecutivos onde não foi observado a redução da hiperalgesia, mas ocorreu a redução do edema. A associação do ultra-som com a indometacina, nas doses j á citadas anteriormente, conseguiu inibir significativamente a hiperalgesia e o edema das patas dos ratos artríticos. Em nossos estudos, concluímos que o ultra-som associado à indometacina foi mais efetivo do que quando a indometacina ou ultra-som foram utilizados isoladamente na inibição da hiperalgesia e no edema de ratos artríticos.Universidade de São Paulo. Faculdade de Medicina1998-12-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/fpusp/article/view/7728910.1590/fpusp.v5i2.77289Fisioterapia e Pesquisa; Vol. 5 No. 2 (1998); 83-96Fisioterapia e Pesquisa; Vol. 5 Núm. 2 (1998); 83-96Fisioterapia e Pesquisa; v. 5 n. 2 (1998); 83-962316-91171809-2950reponame:Fisioterapia e Pesquisainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/fpusp/article/view/77289/81156Copyright (c) 2017 Fisioterapia e Pesquisainfo:eu-repo/semantics/openAccessPereira, Leani Souza MáximoFrancischi, Janetti Nogueira deSilva, Fabrícia Mendes Pereira eSantos, Ândrea Marília CostaTiradentes, Kamile AlmeidaCarmo, Simone Caldeira2014-05-07T22:47:47Zoai:revistas.usp.br:article/77289Revistahttp://www.revistas.usp.br/fpuspPUBhttps://www.revistas.usp.br/fpusp/oai||revfisio@usp.br2316-91171809-2950opendoar:2014-05-07T22:47:47Fisioterapia e Pesquisa - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats Os efeitos do ultra-som na hyperalgesia e no edema de ratos artríticos |
title |
Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats |
spellingShingle |
Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats Pereira, Leani Souza Máximo Terapia por ultrassom métodos Envelhecimento Fisioterapia reabilitação Hiperalgesia Artrite Edemas Ultrasonic therapy methods Aging Physical therapy reabilitação Hyperalgesia Arthritis rheumatoid rehabilitation Edema |
title_short |
Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats |
title_full |
Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats |
title_fullStr |
Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats |
title_full_unstemmed |
Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats |
title_sort |
Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats |
author |
Pereira, Leani Souza Máximo |
author_facet |
Pereira, Leani Souza Máximo Francischi, Janetti Nogueira de Silva, Fabrícia Mendes Pereira e Santos, Ândrea Marília Costa Tiradentes, Kamile Almeida Carmo, Simone Caldeira |
author_role |
author |
author2 |
Francischi, Janetti Nogueira de Silva, Fabrícia Mendes Pereira e Santos, Ândrea Marília Costa Tiradentes, Kamile Almeida Carmo, Simone Caldeira |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pereira, Leani Souza Máximo Francischi, Janetti Nogueira de Silva, Fabrícia Mendes Pereira e Santos, Ândrea Marília Costa Tiradentes, Kamile Almeida Carmo, Simone Caldeira |
dc.subject.por.fl_str_mv |
Terapia por ultrassom métodos Envelhecimento Fisioterapia reabilitação Hiperalgesia Artrite Edemas Ultrasonic therapy methods Aging Physical therapy reabilitação Hyperalgesia Arthritis rheumatoid rehabilitation Edema |
topic |
Terapia por ultrassom métodos Envelhecimento Fisioterapia reabilitação Hiperalgesia Artrite Edemas Ultrasonic therapy methods Aging Physical therapy reabilitação Hyperalgesia Arthritis rheumatoid rehabilitation Edema |
description |
With the population aging, the prevalence of chronic diseases of muscles and joints restricting in the elderly functional capacity has been increasing. The rheumatoid arthritis is part of this group of pathologies and the treatment of the disease has been basically to reduce the symptoms as pain, edema, rigidity, muscular atrophies through the inhibition of the inflammatory process. For this, treatments with drugs and treatment with physical therapeutics resources are used. The ultrasound is a physical therapeutic resource that has been used thoroughly in the clinical practice with the objective of solving the inflammatory process of the rheumatoid arthritis. The effect of the ultra-sound was observed on the edema and on the hyperalgesia of the posterior paws of arthritic rats. The rheumatoid arthritis was induced through an injection of an emulsion oil-water contends 400 ?g of Micobacierium butiricum. The hyperalgesia was detected in the 11 st day and the edema in the 12nd day after the induction of the rheumatoid arthritis. For comparative study, it was administered the indometacina orally in the dose of 0,5 mg/kg/dia during 15 days where we didn't observe reduction of the hyperalgesia but there was reduction of the edema of the posterior paws of the arthritic rats. The ultrasound in the frequency of 1 MHz. intensity 0,2 watts/cm2, for 5 minutes, for 15 days didn't reduce the hyperalgesia or edema of the posterior paws of the arthritic rats. The association of the ultrasound with the indomethacin in the doses already mentioned previously got to inhibit the hyperalgesia and edema of the posterior paws of the arthritic rats significantly. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-12-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/fpusp/article/view/77289 10.1590/fpusp.v5i2.77289 |
url |
https://www.revistas.usp.br/fpusp/article/view/77289 |
identifier_str_mv |
10.1590/fpusp.v5i2.77289 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/fpusp/article/view/77289/81156 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Fisioterapia e Pesquisa info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Fisioterapia e Pesquisa |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina |
dc.source.none.fl_str_mv |
Fisioterapia e Pesquisa; Vol. 5 No. 2 (1998); 83-96 Fisioterapia e Pesquisa; Vol. 5 Núm. 2 (1998); 83-96 Fisioterapia e Pesquisa; v. 5 n. 2 (1998); 83-96 2316-9117 1809-2950 reponame:Fisioterapia e Pesquisa instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Fisioterapia e Pesquisa |
collection |
Fisioterapia e Pesquisa |
repository.name.fl_str_mv |
Fisioterapia e Pesquisa - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||revfisio@usp.br |
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1787713735790428160 |