Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats

Detalhes bibliográficos
Autor(a) principal: Busarello, Fernanda de Oliveira
Data de Publicação: 2011
Outros Autores: Artifon, Elisângela Lourdes, Loth, Eduardo Alexandre, Bertolini, Gladson Ricardo Flor
Tipo de documento: Artigo
Idioma: por
Título da fonte: Fisioterapia e Pesquisa
Texto Completo: https://www.revistas.usp.br/fpusp/article/view/12281
Resumo: The commitment of immune system, which may be presented by individuals with chronic diseases, leading to a low immune response. One of the treatments used for acute injuries in tendons is the low-power laser, however there is a gap in relation to its use in immunosuppression. The objective of this study was to analyze if low-level laser therapy is effective for the treatment of pain in immunosuppressed rats subjected to trauma tendon. We used 23 male rats of Wistar strain, divided randomly in three groups: control group, placebo and laser. The animals were immunosuppressed (by administration of Cyclosporin A) and underwent right Achilles tendon injury, with impact of about 0.40 J. For treatment, we used low-level laser, 670 nm, 30 mW and 2 J/cm², during 3 days. Pain assessment was performed by the functional incapacitation test and von Frey filament digital. The results showed a reduction of functional pain and pressure pain on the plantar surface and the injured site (right Achilles tendon) for the laser group. Therefore, we concluded that the low-power laser is effective for reducing pain in immunosuppressed rats subjected to trauma tendon.
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spelling Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats Análise da eficácia do laser de baixa potência no tratamento da dor tendínea em ratos imunossuprimidos terapia a laser de baixa intensidadetendão do calcâneotendinopatiamedição da dorlaser therapylow-levelAchilles tendontendinopathypain measurement The commitment of immune system, which may be presented by individuals with chronic diseases, leading to a low immune response. One of the treatments used for acute injuries in tendons is the low-power laser, however there is a gap in relation to its use in immunosuppression. The objective of this study was to analyze if low-level laser therapy is effective for the treatment of pain in immunosuppressed rats subjected to trauma tendon. We used 23 male rats of Wistar strain, divided randomly in three groups: control group, placebo and laser. The animals were immunosuppressed (by administration of Cyclosporin A) and underwent right Achilles tendon injury, with impact of about 0.40 J. For treatment, we used low-level laser, 670 nm, 30 mW and 2 J/cm², during 3 days. Pain assessment was performed by the functional incapacitation test and von Frey filament digital. The results showed a reduction of functional pain and pressure pain on the plantar surface and the injured site (right Achilles tendon) for the laser group. Therefore, we concluded that the low-power laser is effective for reducing pain in immunosuppressed rats subjected to trauma tendon. O comprometimento do sistema imune, que pode ser apresentado por indivíduos com doenças crônicas, leva à baixa resposta imunológica. Um dos tratamentos utilizados para lesões agudas em tendões é o laser de baixa potência, contudo há uma lacuna em relação ao seu uso em imunodepressão. O objetivo do presente estudo foi analisar se o laser de baixa potência é eficaz para o tratamento da dor em ratos imunodeprimidos submetidos a trauma tendíneo. Foram utilizados 23 ratos, machos, da linhagem Wistar, divididos aleatoriamente em três grupos: grupo controle, placebo e laser. Os animais foram imunodeprimidos (por administração de Ciclosporina A) e submetidos à lesão no tendão calcâneo direito, com impacto de cerca de 0,40 J. Para o tratamento, utilizou-se laser de baixa potência, 670 nm, 30 mW e dose de 2 J/cm², durante 3 dias. A avaliação da dor foi realizada pelo teste de incapacidade funcional e por filamento de Von Frey digital. Os resultados apresentaram valores significativos para o grupo laser, com diminuição de dor funcional e da dor à pressão na superfície plantar e no local lesionado (tendão calcâneo direito). Portanto, concluiu-se que o laser de baixa potência é eficaz para reduzir a dor em ratos imunodeprimidos submetidos a trauma tendíneo. Universidade de São Paulo. Faculdade de Medicina2011-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/fpusp/article/view/1228110.1590/S1809-29502011000400007Fisioterapia e Pesquisa; Vol. 18 No. 4 (2011); 335-340 Fisioterapia e Pesquisa; Vol. 18 Núm. 4 (2011); 335-340 Fisioterapia e Pesquisa; v. 18 n. 4 (2011); 335-340 2316-91171809-2950reponame:Fisioterapia e Pesquisainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/fpusp/article/view/12281/14058Copyright (c) 2017 Fisioterapia e Pesquisainfo:eu-repo/semantics/openAccessBusarello, Fernanda de OliveiraArtifon, Elisângela LourdesLoth, Eduardo AlexandreBertolini, Gladson Ricardo Flor2012-05-13T16:07:58Zoai:revistas.usp.br:article/12281Revistahttp://www.revistas.usp.br/fpuspPUBhttps://www.revistas.usp.br/fpusp/oai||revfisio@usp.br2316-91171809-2950opendoar:2012-05-13T16:07:58Fisioterapia e Pesquisa - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats
Análise da eficácia do laser de baixa potência no tratamento da dor tendínea em ratos imunossuprimidos
title Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats
spellingShingle Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats
Busarello, Fernanda de Oliveira
terapia a laser de baixa intensidade
tendão do calcâneo
tendinopatia
medição da dor
laser therapy
low-level
Achilles tendon
tendinopathy
pain measurement
title_short Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats
title_full Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats
title_fullStr Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats
title_full_unstemmed Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats
title_sort Analysis of low-level laser therapy efficacy on tendon pain treatment in immunosuppressed rats
author Busarello, Fernanda de Oliveira
author_facet Busarello, Fernanda de Oliveira
Artifon, Elisângela Lourdes
Loth, Eduardo Alexandre
Bertolini, Gladson Ricardo Flor
author_role author
author2 Artifon, Elisângela Lourdes
Loth, Eduardo Alexandre
Bertolini, Gladson Ricardo Flor
author2_role author
author
author
dc.contributor.author.fl_str_mv Busarello, Fernanda de Oliveira
Artifon, Elisângela Lourdes
Loth, Eduardo Alexandre
Bertolini, Gladson Ricardo Flor
dc.subject.por.fl_str_mv terapia a laser de baixa intensidade
tendão do calcâneo
tendinopatia
medição da dor
laser therapy
low-level
Achilles tendon
tendinopathy
pain measurement
topic terapia a laser de baixa intensidade
tendão do calcâneo
tendinopatia
medição da dor
laser therapy
low-level
Achilles tendon
tendinopathy
pain measurement
description The commitment of immune system, which may be presented by individuals with chronic diseases, leading to a low immune response. One of the treatments used for acute injuries in tendons is the low-power laser, however there is a gap in relation to its use in immunosuppression. The objective of this study was to analyze if low-level laser therapy is effective for the treatment of pain in immunosuppressed rats subjected to trauma tendon. We used 23 male rats of Wistar strain, divided randomly in three groups: control group, placebo and laser. The animals were immunosuppressed (by administration of Cyclosporin A) and underwent right Achilles tendon injury, with impact of about 0.40 J. For treatment, we used low-level laser, 670 nm, 30 mW and 2 J/cm², during 3 days. Pain assessment was performed by the functional incapacitation test and von Frey filament digital. The results showed a reduction of functional pain and pressure pain on the plantar surface and the injured site (right Achilles tendon) for the laser group. Therefore, we concluded that the low-power laser is effective for reducing pain in immunosuppressed rats subjected to trauma tendon.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/fpusp/article/view/12281
10.1590/S1809-29502011000400007
url https://www.revistas.usp.br/fpusp/article/view/12281
identifier_str_mv 10.1590/S1809-29502011000400007
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/fpusp/article/view/12281/14058
dc.rights.driver.fl_str_mv Copyright (c) 2017 Fisioterapia e Pesquisa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Fisioterapia e Pesquisa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina
dc.source.none.fl_str_mv Fisioterapia e Pesquisa; Vol. 18 No. 4 (2011); 335-340
Fisioterapia e Pesquisa; Vol. 18 Núm. 4 (2011); 335-340
Fisioterapia e Pesquisa; v. 18 n. 4 (2011); 335-340
2316-9117
1809-2950
reponame:Fisioterapia e Pesquisa
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Fisioterapia e Pesquisa
collection Fisioterapia e Pesquisa
repository.name.fl_str_mv Fisioterapia e Pesquisa - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||revfisio@usp.br
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