Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles

Detalhes bibliográficos
Autor(a) principal: Alfredo, Patrícia Pereira
Data de Publicação: 2008
Outros Autores: Anaruma, Carlos Alberto, Pião, Antônio Carlos Simões, João, Sílvia Maria Amado, Casarotto, Raquel Aparecida
Tipo de documento: Artigo
Idioma: por
Título da fonte: Fisioterapia e Pesquisa
Texto Completo: https://www.revistas.usp.br/fpusp/article/view/12044
Resumo: This study aimed at verifying the effects of phonophoresis associated to Arnica montana on the acute phase of an inflammatory muscle injury. Forty Wistar male rats of which the Tibialis Anterior muscle was surgically lesioned, were divided into 4 groups (n=10 each): control group received no treatment; the ultrasound group (US), treated with US; the US+A group was treated with arnica phonophoresis; and the arnica group (A) received massage with arnica gel. Treatment for the three groups started 24 h after surgical injury and lasted 3 days, being applied during 3 minutes once a day. On the 4th day after lesion animals were sacrificed and sections of the injured, inflamed muscle were removed for histological analysis. Results showed, in C group, an intense infiltrate of inflammatory cells and an only incipient regeneration process; in both US and US+A groups an advanced inflammatory process was noticed, with organized and thick conjunctive tissue. In A group a reduced number of ill-arranged inflammatory cells was detected, which might lead to delays in the regeneration process. Since both US and US+A groups showed similar acceleration of the acute inflammatory process, it may be inferred that arnica phonophoresis did not have extra healing effect, hence is inneffective when compared to ultrasound alone.
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spelling Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles Análise qualitativa dos efeitos da sonoforese com Arnica montana sobre o processo inflamatório agudo do músculo esquelético de ratos ArnicaFonoforeseMúsculo esquelético/anatomia & histologiaTerapia por ultra-somArnicaMuscleskeletal/anatomy & histologyPhonophoresisUltrasonic therapy This study aimed at verifying the effects of phonophoresis associated to Arnica montana on the acute phase of an inflammatory muscle injury. Forty Wistar male rats of which the Tibialis Anterior muscle was surgically lesioned, were divided into 4 groups (n=10 each): control group received no treatment; the ultrasound group (US), treated with US; the US+A group was treated with arnica phonophoresis; and the arnica group (A) received massage with arnica gel. Treatment for the three groups started 24 h after surgical injury and lasted 3 days, being applied during 3 minutes once a day. On the 4th day after lesion animals were sacrificed and sections of the injured, inflamed muscle were removed for histological analysis. Results showed, in C group, an intense infiltrate of inflammatory cells and an only incipient regeneration process; in both US and US+A groups an advanced inflammatory process was noticed, with organized and thick conjunctive tissue. In A group a reduced number of ill-arranged inflammatory cells was detected, which might lead to delays in the regeneration process. Since both US and US+A groups showed similar acceleration of the acute inflammatory process, it may be inferred that arnica phonophoresis did not have extra healing effect, hence is inneffective when compared to ultrasound alone. Este estudo visou verificar o efeito da sonoforese com Arnica montana sobre a fase inflamatória aguda de uma lesão muscular. Para isso, 40 ratos Wistar machos, lesados cirurgicamente, foram divididos em 4 grupos: controle (C), 10 ratos lesados e não tratados; grupo ultra-som (US), 10 lesados, tratados com US; grupo ultra-som com arnica (US+A), 10 ratos lesados, tratados com sonoforese de gel de arnica; grupo arnica (A), 10 ratos lesados, tratados com massagem de gel de arnica. O tratamento dos três grupos foi iniciado 24h após a lesão, sendo aplicado uma vez ao dia durante 3 minutos, por três dias. Quatro dias após a lesão, os animais foram sacrificados e o terço médio do músculo tibial anterior lesado foi removido e tratado histologicamente. Os resultados da análise qualitativa mostram que, no grupo C, formou-se um intenso infiltrado de células inflamatórias no espaço intersticial e um processo de regeneração apenas iniciado. Nos grupos US e US+A foi detectado um avançado processo inflamatório, com tecido conjuntivo mais organizado e consistente. No grupo A foi detectada diminuição no número de células inflamatórias e uma desorganização em sua disposição, o que poderia levar a um atraso no processo de regeneração. Conclui-se que os grupos que receberam a aplicação do ultra-som e ultra-som com arnica apresentaram semelhante aceleração do processo inflamatório agudo, sugerindo ineficácia da sonoforese quando comparada à aplicação de apenas ultra-som. Universidade de São Paulo. Faculdade de Medicina2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/fpusp/article/view/1204410.1590/S1809-29502008000300010Fisioterapia e Pesquisa; Vol. 15 No. 3 (2008); 273-279 Fisioterapia e Pesquisa; Vol. 15 Núm. 3 (2008); 273-279 Fisioterapia e Pesquisa; v. 15 n. 3 (2008); 273-279 2316-91171809-2950reponame:Fisioterapia e Pesquisainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/fpusp/article/view/12044/13821Copyright (c) 2017 Fisioterapia e Pesquisainfo:eu-repo/semantics/openAccessAlfredo, Patrícia PereiraAnaruma, Carlos AlbertoPião, Antônio Carlos SimõesJoão, Sílvia Maria AmadoCasarotto, Raquel Aparecida2012-05-13T15:50:12Zoai:revistas.usp.br:article/12044Revistahttp://www.revistas.usp.br/fpuspPUBhttps://www.revistas.usp.br/fpusp/oai||revfisio@usp.br2316-91171809-2950opendoar:2012-05-13T15:50:12Fisioterapia e Pesquisa - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles
Análise qualitativa dos efeitos da sonoforese com Arnica montana sobre o processo inflamatório agudo do músculo esquelético de ratos
title Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles
spellingShingle Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles
Alfredo, Patrícia Pereira
Arnica
Fonoforese
Músculo esquelético/anatomia & histologia
Terapia por ultra-som
Arnica
Muscle
skeletal/anatomy & histology
Phonophoresis
Ultrasonic therapy
title_short Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles
title_full Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles
title_fullStr Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles
title_full_unstemmed Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles
title_sort Qualitative analysis of effects of phonophoresis with Arnica montana onto acute inflammatory process in rat skeletal muscles
author Alfredo, Patrícia Pereira
author_facet Alfredo, Patrícia Pereira
Anaruma, Carlos Alberto
Pião, Antônio Carlos Simões
João, Sílvia Maria Amado
Casarotto, Raquel Aparecida
author_role author
author2 Anaruma, Carlos Alberto
Pião, Antônio Carlos Simões
João, Sílvia Maria Amado
Casarotto, Raquel Aparecida
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Alfredo, Patrícia Pereira
Anaruma, Carlos Alberto
Pião, Antônio Carlos Simões
João, Sílvia Maria Amado
Casarotto, Raquel Aparecida
dc.subject.por.fl_str_mv Arnica
Fonoforese
Músculo esquelético/anatomia & histologia
Terapia por ultra-som
Arnica
Muscle
skeletal/anatomy & histology
Phonophoresis
Ultrasonic therapy
topic Arnica
Fonoforese
Músculo esquelético/anatomia & histologia
Terapia por ultra-som
Arnica
Muscle
skeletal/anatomy & histology
Phonophoresis
Ultrasonic therapy
description This study aimed at verifying the effects of phonophoresis associated to Arnica montana on the acute phase of an inflammatory muscle injury. Forty Wistar male rats of which the Tibialis Anterior muscle was surgically lesioned, were divided into 4 groups (n=10 each): control group received no treatment; the ultrasound group (US), treated with US; the US+A group was treated with arnica phonophoresis; and the arnica group (A) received massage with arnica gel. Treatment for the three groups started 24 h after surgical injury and lasted 3 days, being applied during 3 minutes once a day. On the 4th day after lesion animals were sacrificed and sections of the injured, inflamed muscle were removed for histological analysis. Results showed, in C group, an intense infiltrate of inflammatory cells and an only incipient regeneration process; in both US and US+A groups an advanced inflammatory process was noticed, with organized and thick conjunctive tissue. In A group a reduced number of ill-arranged inflammatory cells was detected, which might lead to delays in the regeneration process. Since both US and US+A groups showed similar acceleration of the acute inflammatory process, it may be inferred that arnica phonophoresis did not have extra healing effect, hence is inneffective when compared to ultrasound alone.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/fpusp/article/view/12044
10.1590/S1809-29502008000300010
url https://www.revistas.usp.br/fpusp/article/view/12044
identifier_str_mv 10.1590/S1809-29502008000300010
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/fpusp/article/view/12044/13821
dc.rights.driver.fl_str_mv Copyright (c) 2017 Fisioterapia e Pesquisa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Fisioterapia e Pesquisa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina
dc.source.none.fl_str_mv Fisioterapia e Pesquisa; Vol. 15 No. 3 (2008); 273-279
Fisioterapia e Pesquisa; Vol. 15 Núm. 3 (2008); 273-279
Fisioterapia e Pesquisa; v. 15 n. 3 (2008); 273-279
2316-9117
1809-2950
reponame:Fisioterapia e Pesquisa
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Fisioterapia e Pesquisa
collection Fisioterapia e Pesquisa
repository.name.fl_str_mv Fisioterapia e Pesquisa - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||revfisio@usp.br
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