Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?

Detalhes bibliográficos
Autor(a) principal: Freitas, Rodrigo Pegado de Abreu
Data de Publicação: 2013
Outros Autores: Barcelos, Ana Paula Medeiros de, Nóbrega, Brenda Medeiros da, Macedo, Aline Barbosa, Oliveira, Anderson Rodrigues de, Ramos, Ana Maria de Oliveira, Vieira, Wouber Hérickson de Brito
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Fisioterapia e Pesquisa
Texto Completo: https://www.revistas.usp.br/fpusp/article/view/78343
Resumo: This study aimed to investigate if there are differences between the associated and isolated therapies from the laser and micro current on healing of burn wound healing in rats. A total of 40 male rats were randomly allocated into four groups: control group (CG), micro current group (MG), laser group (LG) and laser/micro current group (LMG), treated with associated laser and micro current. Thermal damage was done on the back of the animal and a total of ten days therapy was performed. After treatment samples were taken from the lesions to perform semi quantitative histopathological study using Hematoxylin Eosin and Masson Trichrome. The Kruskal-Wallis and Dunn's Test were used for statistical analyses. We observed a significant difference between groups for production of fibroblasts (p=0.0003), collagen (p=0.0153), neoangiogenesis (p=0.0031) and skin annexes (p=0.0004). In semi-quantitative histological analysis, the LMG showed lower values in presence of collagen, fibroblasts and number of skin appendages, only for neoangiogenesis, the associated therapy showed similar values to single modality therapy groups. Laser and microcurrent have beneficial effects on tissue healing. However, it is suggested that the association of these two therapies reduces the effectiveness of the treatment when compared to single mode treatment.
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spelling Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas? Laserterapia y microcorriente en la cicatrización de quemaduras en ratas: ¿terapias asociadas o aisladas? Low-level laser therapy and micro current in burn wound healing in rats: associated or isolated therapy? This study aimed to investigate if there are differences between the associated and isolated therapies from the laser and micro current on healing of burn wound healing in rats. A total of 40 male rats were randomly allocated into four groups: control group (CG), micro current group (MG), laser group (LG) and laser/micro current group (LMG), treated with associated laser and micro current. Thermal damage was done on the back of the animal and a total of ten days therapy was performed. After treatment samples were taken from the lesions to perform semi quantitative histopathological study using Hematoxylin Eosin and Masson Trichrome. The Kruskal-Wallis and Dunn's Test were used for statistical analyses. We observed a significant difference between groups for production of fibroblasts (p=0.0003), collagen (p=0.0153), neoangiogenesis (p=0.0031) and skin annexes (p=0.0004). In semi-quantitative histological analysis, the LMG showed lower values in presence of collagen, fibroblasts and number of skin appendages, only for neoangiogenesis, the associated therapy showed similar values to single modality therapy groups. Laser and microcurrent have beneficial effects on tissue healing. However, it is suggested that the association of these two therapies reduces the effectiveness of the treatment when compared to single mode treatment. Este estudio tiene el objetivo de investigar si hay diferencias entre las terapias asociadas y aisladas del láser y microcorrientes en la reparación de lesión por quemadura en ratas. Un total de 40 animales fueron divididos aleatoriamente en cuatro grupos: grupo control (GC), grupo microcorriente (GM), grupo láser (GL) y grupo láser/microcorriente (GLM), tratados con láser asociado a microcorrientes. Después de inducidas las lesiones térmicas en el dorso del animal, fueron realizados en total diez días de tratamiento. Las muestras de tejido fueron recolectadas para el estudio histopatológico semicuantitativo usando Hematoxilina Eosina y Tricómico de Masson. Fueron utilizados los tests de Kruskal-Wallis y post-hoc de Dunn's. Hubo diferencia significativa entre los grupos para la producción de fibroblastos (p=0,0003), colágeno (p=0,0153), neoangiogénesis (p=0,0031) y anexos cutáneos (p=0,0004). En el análisis histológico semicuantitativo, el GLM presentó valores menores en los parámetros histológicos de presencia de colágeno, número de fibroblastos y anexos cutáneos (p Este estudo teve o objetivo de investigar se há diferenças entre as terapias associadas e isoladas do laser e microcorrentes no reparo de lesão por queimadura em ratos. Um total de 40 animais foi dividido aleatoriamente em quatro grupos: grupo controle (GC); grupo microcorrente (GM), grupo laser (GL) e grupo laser/microcorrente (GLM), tratados com laser associado a microcorrentes. Após lesões térmicas induzidas no dorso do animal, foi realizado um total de dez dias de tratamento. Amostras do tecido foram coletadas para estudo histopatológico semiquantitativo com Hematoxilina Eosina e Tricrômico de Masson. Foram utilizados os testes de Kruskal-Wallis e post-hoc de Dunn. Houve diferença significativa entre os grupos para a produção de fibroblastos (p=0,0003), colágeno (p=0,0153), neoangiogênese (p=0,0031) e anexos cutâneos (p=0,0004). Na análise histológica semiquantitativa, o GLM apresentou valores menores nos parâmetros histológicos de presença de colágeno, número de fibroblastos e anexos cutâneos (pUniversidade de São Paulo. Faculdade de Medicina2013-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.revistas.usp.br/fpusp/article/view/7834310.1590/S1809-29502013000100005Fisioterapia e Pesquisa; Vol. 20 No. 1 (2013); 24-30Fisioterapia e Pesquisa; Vol. 20 Núm. 1 (2013); 24-30Fisioterapia e Pesquisa; v. 20 n. 1 (2013); 24-302316-91171809-2950reponame:Fisioterapia e Pesquisainstname:Universidade de São Paulo (USP)instacron:USPporenghttps://www.revistas.usp.br/fpusp/article/view/78343/82354https://www.revistas.usp.br/fpusp/article/view/78343/82355Copyright (c) 2017 Fisioterapia e Pesquisainfo:eu-repo/semantics/openAccessFreitas, Rodrigo Pegado de AbreuBarcelos, Ana Paula Medeiros deNóbrega, Brenda Medeiros daMacedo, Aline BarbosaOliveira, Anderson Rodrigues deRamos, Ana Maria de OliveiraVieira, Wouber Hérickson de Brito2014-04-02T17:27:22Zoai:revistas.usp.br:article/78343Revistahttp://www.revistas.usp.br/fpuspPUBhttps://www.revistas.usp.br/fpusp/oai||revfisio@usp.br2316-91171809-2950opendoar:2014-04-02T17:27:22Fisioterapia e Pesquisa - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?
Laserterapia y microcorriente en la cicatrización de quemaduras en ratas: ¿terapias asociadas o aisladas?
Low-level laser therapy and micro current in burn wound healing in rats: associated or isolated therapy?
title Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?
spellingShingle Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?
Freitas, Rodrigo Pegado de Abreu
title_short Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?
title_full Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?
title_fullStr Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?
title_full_unstemmed Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?
title_sort Laserterapia e microcorrente na cicatrização de queimadura em ratos: terapias associadas ou isoladas?
author Freitas, Rodrigo Pegado de Abreu
author_facet Freitas, Rodrigo Pegado de Abreu
Barcelos, Ana Paula Medeiros de
Nóbrega, Brenda Medeiros da
Macedo, Aline Barbosa
Oliveira, Anderson Rodrigues de
Ramos, Ana Maria de Oliveira
Vieira, Wouber Hérickson de Brito
author_role author
author2 Barcelos, Ana Paula Medeiros de
Nóbrega, Brenda Medeiros da
Macedo, Aline Barbosa
Oliveira, Anderson Rodrigues de
Ramos, Ana Maria de Oliveira
Vieira, Wouber Hérickson de Brito
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas, Rodrigo Pegado de Abreu
Barcelos, Ana Paula Medeiros de
Nóbrega, Brenda Medeiros da
Macedo, Aline Barbosa
Oliveira, Anderson Rodrigues de
Ramos, Ana Maria de Oliveira
Vieira, Wouber Hérickson de Brito
description This study aimed to investigate if there are differences between the associated and isolated therapies from the laser and micro current on healing of burn wound healing in rats. A total of 40 male rats were randomly allocated into four groups: control group (CG), micro current group (MG), laser group (LG) and laser/micro current group (LMG), treated with associated laser and micro current. Thermal damage was done on the back of the animal and a total of ten days therapy was performed. After treatment samples were taken from the lesions to perform semi quantitative histopathological study using Hematoxylin Eosin and Masson Trichrome. The Kruskal-Wallis and Dunn's Test were used for statistical analyses. We observed a significant difference between groups for production of fibroblasts (p=0.0003), collagen (p=0.0153), neoangiogenesis (p=0.0031) and skin annexes (p=0.0004). In semi-quantitative histological analysis, the LMG showed lower values in presence of collagen, fibroblasts and number of skin appendages, only for neoangiogenesis, the associated therapy showed similar values to single modality therapy groups. Laser and microcurrent have beneficial effects on tissue healing. However, it is suggested that the association of these two therapies reduces the effectiveness of the treatment when compared to single mode treatment.
publishDate 2013
dc.date.none.fl_str_mv 2013-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/fpusp/article/view/78343
10.1590/S1809-29502013000100005
url https://www.revistas.usp.br/fpusp/article/view/78343
identifier_str_mv 10.1590/S1809-29502013000100005
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/fpusp/article/view/78343/82354
https://www.revistas.usp.br/fpusp/article/view/78343/82355
dc.rights.driver.fl_str_mv Copyright (c) 2017 Fisioterapia e Pesquisa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Fisioterapia e Pesquisa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina
dc.source.none.fl_str_mv Fisioterapia e Pesquisa; Vol. 20 No. 1 (2013); 24-30
Fisioterapia e Pesquisa; Vol. 20 Núm. 1 (2013); 24-30
Fisioterapia e Pesquisa; v. 20 n. 1 (2013); 24-30
2316-9117
1809-2950
reponame:Fisioterapia e Pesquisa
instname:Universidade de São Paulo (USP)
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instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Fisioterapia e Pesquisa
collection Fisioterapia e Pesquisa
repository.name.fl_str_mv Fisioterapia e Pesquisa - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||revfisio@usp.br
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