Stem cells and bioengineering in the current context of dentistry and general health / Células-tronco e bioengenharia no contexto atual da odontologia e saúde geral

• Autor(a) principal: Ambrosio, Marcella Vieira
• Data de Publicação: 2020
• Outros Autores: Neto, João Lopes Toledo, Foggiato, Augusto Alberto, Silva, Douglas Fernandes da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Veras
• Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BRJD/article/view/20492
• topic: mesenchymal stem cells; odontology; culture medium; bioengineering; SARS-CoV-2.

Mesenchymal stem cells (MSC) are undifferentiated cell structures with the ability to both renew themselves and differentiate into different specialized cell types. These can be found in some structures of the dental organ, such as in the dental pulp, in the periodontal ligament, in the dental follicle and in the apical papilla, changing to being called dental stem cells (DSC). When compared with other types of MSC, DSC have the benefit of being obtained in a minimally invasive and painless way. These particularities make them the ideal tool for applicability in dental and non-dental therapies. In this review was emphasize that, in an appropriate culture medium, DSC can be used for the restoration of dental structures, in the repair of nervous and bone tissue and in the treatment of neurodegenerative, hepatic and ocular deficits. In addition, in the current context of COVID-19, MSC are being investigated and applied to treat complications caused by the new coronavirus, which has been extended to DSC. In summary, this review article concludes that understanding the functioning of these cells and their properties may allow the development of more effective treatments or even the cure of several pathologies.