Differential diagnosis of pulmonary Sarcoidosis in an elderly patient: case report/ Diagnóstico diferencial de Sarcoidose pulmonar em um paciente idoso: relato de caso

• Autor(a) principal: Filho, Reinaldo Leite de Morais
• Data de Publicação: 2021
• Outros Autores: Figueiredo, Bárbara Queiroz de, Dutra, Dalbert Samuel, Teixeira, Janayna Fraga, Gonçalves, Luanna Oliveira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Veras
• Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BRJD/article/view/41003
• topic: Pulmonary sarcoidosis; Diagnosis; Transbronchial biopsy.

INTRODUCTION: Sarcoidosis is a worldwide disease with a lifetime incidence rate of 0.85–2.4%, generally affecting people between 25 and 40 years of age. The clinical phenotype of sarcoidosis can be extremely diverse in terms of presentation, involved organs, duration and severity, however, pulmonary involvement is present in 86–92% of cases according to chest radiography, alone or in association with locations extrapulmonary in about 50% of cases. PURPOSE: to demonstrate a clinical case, by differential diagnosis, of pulmonary sarcoidosis. METHODOLOGY: this is a clinical case study with a qualitative and descriptive perspective, which consists of research that, in general, takes place with direct data collection, whose researcher is the indispensable instrument. CASE REPORT: elderly patient, who, after admission to the emergency room, had symptoms such as mental confusion, wasting syndrome, with previous imaging exams without alterations. The results of transbronchial biopsy showed foci of fibrosis in the lamina propria and non-caseating epithelioid granulomatous inflammation in the lung parenchyma, as well as negative Baar and fungus tests. From this perspective, the differential diagnosis was found, closing the clinical case for pulmonary sarcoidosis. DISCUSSION: The diversity of the sarcoidosis phenotype is often linked to epidemiological factors and, interestingly, as shown by recent studies, to the genotype. FINAL CONSIDERATIONS: sarcoidosis is a frequent but multifaceted disease that still poses diagnostic and therapeutic challenges.