Cesarean delivery modulate intestinal microbiome and th9 cell asnwer propensity to allergic diseases? / A modulação do microbioma intestinal por influência do parto cesariana possui correlação com a resposta das células th9 em doenças alérgicas?

• Autor(a) principal: Feitosa, Ivan Brito
• Data de Publicação: 2021
• Outros Autores: Leite, Cleber Queiroz, Medeiros, Jade Gomes da Costa, de Medeiros, Lara Graziela Fernandes Maia, Boas, Amanda Nascimento Vilas, Saldanha, Bruna Pechim, Peres, Julia Garcia, Marcelino, Rafaela Calaça, da Silva, Poliana Alves, Tortora, Nathália Soave
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Veras
• Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BRJD/article/view/27150
• topic: Intestinal microbiota. Helper T cells. Th9.

The type of birth can alter the composition of the human intestinal microbiota and crucially interfere in the formation of the innate and adaptive immune system. Among the various cell groups that can be modulated by the type of delivery are helper T cells (Th). Currently, in addition to the classic Th1 and Th2 profile, other subsets have been identified including Th17, Th22, Th25 and Th9.  Studies on the modulation of T helper lymphocytes associated with the type of birth are still emerging. However, it is known that the action of Th9 cells is modulated according to the intestinal microbiota. Thus, this study aimed to describe how the type of birth, vaginal or cesarean, can change the intestinal microbiota and we hypothesized that the form of delivery changes the pattern of response to Th9 in allergic diseases.