Anatomopathological and immunohistochemical characterization of a case of granulomatous meningoencephalitis in a bovine with systemic tuberculosis / Caracterização anatomopatológica e imuno-histoquímica de um caso de meningite granulomatosa em bovino com tuberculose sistêmica

• Autor(a) principal: Lazzaretti, Renan
• Data de Publicação: 2022
• Outros Autores: Santos, Ezequiel Davi dos, Setim, Diorges Henrique, Machado, Tanise Policarpo, Seibel, Renata, Bondan, Carlos, Zanella, Ricardo, Ritterbusch, Giseli Aparecida, Motta, Adriana Costa da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Veras
• Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BRJD/article/view/48783
• topic: meningitis; tuberculosis; zoonosis; bovine; immunohistochemistry.

A two-year-old male bovine of Aberdeen Angus breed with anorexia, weight loss, and apathy was reported for necropsy, being diagnosed with systemic tuberculosis and tuberculoid meningitis lesions. Bovine tuberculosis was observed and confirmed through the necropsy of granulomatous lesions, mainly in the lungs and regional lymph nodes; specific staining for alcohol-acid resistant bacilli and immunohistochemistry were also performed. It should be noted that bovine tuberculosis is a zoonotic disease, with mandatory notification, caused by Mycobacterium bovis. In most cases, it has nonspecific clinical symptoms, such as respiratory signs, weight loss, and lymphadenopathy. In rare cases, alterations in the central nervous system occur. Therefore, this study aimed to report a case of granulomatous meningitis in a bovine with systemic tuberculosis through the characterization of its anatomicopathological and immunohistochemical aspects.