Antibacterial and antibiofilm activity of Physalis peruviana calyx extract / Atividade antibacteriana e antibiofilme do extrato do cálice de Physalis peruviana

• Autor(a) principal: Bazana, Maiara Taís
• Data de Publicação: 2020
• Outros Autores: Missel, Marcos Vinícius, Deus, Cassandra de, Pinto, Vandré Sonza, Codevilla, Cristiane Franco, Santos, Roberto Christ Vianna, Silva, Cristiane de Bona da, Menezes, Cristiano Ragagnin de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Veras
• Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BRJD/article/view/18140
• topic: biofilm; goldenberry; minimum inhibitory concentration; minimum bactericidal concentration.

This study aimed to evaluate the antibacterial and antibiofilm activity of a P. peruviana calyx extract. Goldenberry calyx extracts were prepared with 60% (v/v) ethanol. Minimum inhibitory concentration (MIC) analyses were performed by the 96-well plate microdilution method together with the minimum bactericidal concentration (MBC). Biofilm inhibition and destruction was performed in microdilution plates. The P. peruviana calyx extract presented antibacterial activity against the pathogens analyzed (Enterobacter aerogenes ATCC 13048, Klebsiella pneumoniae ATCC 1705, Staphylococcus epidermidis (clinical isolate), Streptococcus pneumoniae ATCC 99619, Pseudomonas aeruginosa PA01, Enterococcus faecalis ATCC 29212, Escherichia coli (clinical isolate), Shigella sonnei (clinical isolate), Acinetobacter baumannii ATCC 19606, Streptococcus agalactie (clinical isolate), Acinetobacter baumannii (clinical isolate), Salmonella sp. (clinical isolate), Salmonella enteritidis (clinical isolate), and Staphylococcus aureus (clinical isolate)). MIC varied from 3.15 to 30 mg/mL extract and showed bacteriostatic activity against eight pathogens and bactericidal activity at 30 mg/mL concentration against six strains. Biofilm tests revealed biofilm formation inhibition, although there was no destruction. According to these results, the potential antibacterial activity of P. peruviana calyx extract was verified. This will enable further studies to be carried out to contribute to its use in the food industry as a preservative of natural origin and other clinical applications.