Chemical composition and in vitro biological activities of the essential oils of the rhizomes of Zingiber officinale Roscoe and Curcuma longa L. (Zingiberaceae) / Composição química e atividades biológicas in vitro dos óleos essenciais dos rizomas de Zingiber officinale Roscoe e Curcuma longa L. (Zingiberaceae)

• Autor(a) principal: Camilo, Cicera Janaine
• Data de Publicação: 2020
• Outros Autores: Carvalho, Natália Kelly Gomes de, Nonato, Carla de Fatima Alves, Leite, Débora Odília Duarte, Dantas, Alexandro Rodrigues, Pereira, Rafael Caldas, Rodrigues, Fabíola Fernandes Galvão, Costa, José Galberto Martins da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Veras
• DOI: 10.34117/bjdv6n4-084
• Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BRJD/article/view/8502
• topic: Antioxidant; antibiotic modulation; essential oil.

Zingiberofficinale Roscoe and Curcuma longa L. (Zingiberaceae) essential oils were obtained by the hydrodistillation method. The oils offered yields of 0.120% and 0.044% respectively. GC-MS analyzes allowed the identification of 11 constituents in the Curcuma longa essential oil, with major components: ar-turmerone (36.8%), ?-tumerone (32.3%) and curlone (19,2%) For the Zingiberofficinaleessential oil 19 constituents were identified, being: neral (22.9%), zingiberene (15.5%) and geranial (14.9%) the main components. The result of the toxicity test showed significant activity against Artemiasalina for both oils. The dose values required to eliminate 50% (LC50) of the larvae were 100 µg / mL for Z. officinale and 25 µg / mL for C. longa. The antioxidant activity was performed against DPPH free radical. The most significant activity was exhibited by Z. officinale with an IC50 value of 215.8 µg / mL. The antibacterial assay with Z. officinale oil showed efficacy against S. aureus and E. coli, with MIC values of ? 213.3 ?g / mL and 85.3 ?g / mL respectively. For C. longa, MIC values ? 1024 ?g / mL were observed for both bacteria tested. Modulation with aminoglycoside antibiotics showed synergism of C. longa oil combined with amikacin against S. aureus, with a decrease in MIC from 1024 ?g / mL to 14.7 ?g / mL. Meanwhile, the Zingiberofficinale oil obtained a MIC reduction to 6.7 ?g / mL, demonstrating greater efficacy. The results observed here demonstrate the biological potential of the species as cytotoxic and antimicrobial.