Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista brasileira de hematologia e hemoterapia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842009000300005 |
Resumo: | The treatment of iron deficiency anemia in children usually consists in the use of ferrous sulfate solution, but this treatment does not always have the desired effectiveness. The aim of this study was to evaluate the effectiveness of chewable carbonyl iron tablets as an alternative for the treatment of iron deficiency anemia in under six-year-old children. Seventy-three children from Brazilian Family Health Units in Santa Maria, Brazil, were included in this study. One group received chewable carbonyl iron (CI) tablets and a control group received a solution of ferrous sulfate (FS) for 90 days, both at a dose of 5 mg/Kg/day. Blood was drawn from study participants at 0, 30 and 90 days of treatment to evaluate the whole blood test, ferritin concentration, serum iron, and total iron binding capacity. We also evaluated the acceptance and adherence to treatment, and the occurrence of side effects during treatment. Hemoglobin increased 1.3 g/dL in the CI Group and 1.2 g/dL in the FS group during the first 30 days of treatment. After 90 days of treatment, the CI Group had significantly better results for hematocrit, MCV, MCH, iron binding capacity and ferritin concentration compared to the FS Group. The ferritin concentration was significantly higher in the CI Group at the end of the treatment (9.51 ng/mL to 26.16 ng/mL). Additionally, the treatment was better accepted with fewer adverse effects by this group. Chewable carbonyl iron tablets should be considered an important therapeutic option in the treatment of iron deficiency anemia of under six-year-old children. |
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Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old childrenIron deficiency anemiairon carbonylferrous sulfatechildrenThe treatment of iron deficiency anemia in children usually consists in the use of ferrous sulfate solution, but this treatment does not always have the desired effectiveness. The aim of this study was to evaluate the effectiveness of chewable carbonyl iron tablets as an alternative for the treatment of iron deficiency anemia in under six-year-old children. Seventy-three children from Brazilian Family Health Units in Santa Maria, Brazil, were included in this study. One group received chewable carbonyl iron (CI) tablets and a control group received a solution of ferrous sulfate (FS) for 90 days, both at a dose of 5 mg/Kg/day. Blood was drawn from study participants at 0, 30 and 90 days of treatment to evaluate the whole blood test, ferritin concentration, serum iron, and total iron binding capacity. We also evaluated the acceptance and adherence to treatment, and the occurrence of side effects during treatment. Hemoglobin increased 1.3 g/dL in the CI Group and 1.2 g/dL in the FS group during the first 30 days of treatment. After 90 days of treatment, the CI Group had significantly better results for hematocrit, MCV, MCH, iron binding capacity and ferritin concentration compared to the FS Group. The ferritin concentration was significantly higher in the CI Group at the end of the treatment (9.51 ng/mL to 26.16 ng/mL). Additionally, the treatment was better accepted with fewer adverse effects by this group. Chewable carbonyl iron tablets should be considered an important therapeutic option in the treatment of iron deficiency anemia of under six-year-old children.Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842009000300005Revista Brasileira de Hematologia e Hemoterapia v.31 n.3 2009reponame:Revista brasileira de hematologia e hemoterapia (Online)instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)instacron:ABHHTC10.1590/S1516-84842009005000041info:eu-repo/semantics/openAccessFarias,Iria L. G.Colpo,ElisangelaBotton,Salimara R.Silveira,Rosirene B.Fleig,AdrianeSchimitz,Carlos Andre A.Silva,José Edson P.eng2009-08-14T00:00:00Zoai:scielo:S1516-84842009000300005Revistahttp://www.rbhh.org/pt/archivo/https://old.scielo.br/oai/scielo-oai.phpsbhh@terra.com.br||secretaria@rbhh.org1806-08701516-8484opendoar:2009-08-14T00:00Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)false |
dc.title.none.fl_str_mv |
Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children |
title |
Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children |
spellingShingle |
Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children Farias,Iria L. G. Iron deficiency anemia iron carbonyl ferrous sulfate children |
title_short |
Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children |
title_full |
Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children |
title_fullStr |
Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children |
title_full_unstemmed |
Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children |
title_sort |
Carbonyl iron reduces anemia and improves effectiveness of treatment in under six-year-old children |
author |
Farias,Iria L. G. |
author_facet |
Farias,Iria L. G. Colpo,Elisangela Botton,Salimara R. Silveira,Rosirene B. Fleig,Adriane Schimitz,Carlos Andre A. Silva,José Edson P. |
author_role |
author |
author2 |
Colpo,Elisangela Botton,Salimara R. Silveira,Rosirene B. Fleig,Adriane Schimitz,Carlos Andre A. Silva,José Edson P. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Farias,Iria L. G. Colpo,Elisangela Botton,Salimara R. Silveira,Rosirene B. Fleig,Adriane Schimitz,Carlos Andre A. Silva,José Edson P. |
dc.subject.por.fl_str_mv |
Iron deficiency anemia iron carbonyl ferrous sulfate children |
topic |
Iron deficiency anemia iron carbonyl ferrous sulfate children |
description |
The treatment of iron deficiency anemia in children usually consists in the use of ferrous sulfate solution, but this treatment does not always have the desired effectiveness. The aim of this study was to evaluate the effectiveness of chewable carbonyl iron tablets as an alternative for the treatment of iron deficiency anemia in under six-year-old children. Seventy-three children from Brazilian Family Health Units in Santa Maria, Brazil, were included in this study. One group received chewable carbonyl iron (CI) tablets and a control group received a solution of ferrous sulfate (FS) for 90 days, both at a dose of 5 mg/Kg/day. Blood was drawn from study participants at 0, 30 and 90 days of treatment to evaluate the whole blood test, ferritin concentration, serum iron, and total iron binding capacity. We also evaluated the acceptance and adherence to treatment, and the occurrence of side effects during treatment. Hemoglobin increased 1.3 g/dL in the CI Group and 1.2 g/dL in the FS group during the first 30 days of treatment. After 90 days of treatment, the CI Group had significantly better results for hematocrit, MCV, MCH, iron binding capacity and ferritin concentration compared to the FS Group. The ferritin concentration was significantly higher in the CI Group at the end of the treatment (9.51 ng/mL to 26.16 ng/mL). Additionally, the treatment was better accepted with fewer adverse effects by this group. Chewable carbonyl iron tablets should be considered an important therapeutic option in the treatment of iron deficiency anemia of under six-year-old children. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842009000300005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842009000300005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-84842009005000041 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular |
publisher.none.fl_str_mv |
Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular |
dc.source.none.fl_str_mv |
Revista Brasileira de Hematologia e Hemoterapia v.31 n.3 2009 reponame:Revista brasileira de hematologia e hemoterapia (Online) instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) instacron:ABHHTC |
instname_str |
Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) |
instacron_str |
ABHHTC |
institution |
ABHHTC |
reponame_str |
Revista brasileira de hematologia e hemoterapia (Online) |
collection |
Revista brasileira de hematologia e hemoterapia (Online) |
repository.name.fl_str_mv |
Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) |
repository.mail.fl_str_mv |
sbhh@terra.com.br||secretaria@rbhh.org |
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1754213109888712704 |