Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/25948 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil. |
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Pinho, Marcia BerrêdoKalume, Dario E.Correa, Paloma R.Gomes, Leonardo H. F.Pereira, Melissa P.Silva, Renata F. daCastello Branco, Luiz R. R.Degrave, Wim M.Lima, Leila Mendonça2018-04-19T13:40:05Z2018-04-19T13:40:05Z2011PINHO, Márcia Berrêdo; et al. Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur. BMC Microbiology, v.11:80, 12p, 2011.1471-2180https://www.arca.fiocruz.br/handle/icict/2594810.1186/1471-2180-11-80engBioMed CentralMycobacterium bovis BCG MoreuMycobacterium bovis BCG PasteurTuberculosePerfil proteômicoVacina brasileiraM. bovis BCG PasteurTuberculosisBrazilian vaccineMycobacterium bovis BCG MoreauProteomic profileBacille Calmette-GuerinProteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteurinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil.Fundação Ataulpho de Paiva. Centro de Pesquisas Arlindo de Assis. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil.Bacille Calmette-Guerin (BCG) is currently the only available vaccine against tuberculosis (TB) and comprises a heterogeneous family of sub-strains with genotypic and phenotypic differences. The World Health Organization (WHO) affirms that the characterization of BCG sub-strains, both on genomic and proteomic levels, is crucial for a better comprehension of the vaccine. In addition, these studies can contribute in the development of a more efficient vaccine against TB. Here, we combine two-dimensional electrophoresis (2DE) and mass spectrometry to analyse the proteomic profile of culture filtrate proteins (CFPs) from M. bovis BCG Moreau, the Brazilian vaccine strain, comparing it to that of BCG Pasteur. CFPs are considered of great importance given their dominant immunogenicity and role in pathogenesis, being available for interaction with host cells since early infection.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/25948/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALmarcia_pinho_etal_IOC-2011.pdfmarcia_pinho_etal_IOC-2011.pdfapplication/pdf3783223https://www.arca.fiocruz.br/bitstream/icict/25948/2/marcia_pinho_etal_IOC-2011.pdf2205e1a3919a0089ea6c1bdb46d004d4MD52TEXTmarcia_pinho_etal_IOC-2011.pdf.txtmarcia_pinho_etal_IOC-2011.pdf.txtExtracted texttext/plain60190https://www.arca.fiocruz.br/bitstream/icict/25948/3/marcia_pinho_etal_IOC-2011.pdf.txtb050798f33b4e1422d70dbafe9803cd4MD53icict/259482018-08-15 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| dc.title.pt_BR.fl_str_mv |
Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur |
| title |
Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur |
| spellingShingle |
Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur Pinho, Marcia Berrêdo Mycobacterium bovis BCG Moreu Mycobacterium bovis BCG Pasteur Tuberculose Perfil proteômico Vacina brasileira M. bovis BCG Pasteur Tuberculosis Brazilian vaccine Mycobacterium bovis BCG Moreau Proteomic profile Bacille Calmette-Guerin |
| title_short |
Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur |
| title_full |
Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur |
| title_fullStr |
Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur |
| title_full_unstemmed |
Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur |
| title_sort |
Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur |
| author |
Pinho, Marcia Berrêdo |
| author_facet |
Pinho, Marcia Berrêdo Kalume, Dario E. Correa, Paloma R. Gomes, Leonardo H. F. Pereira, Melissa P. Silva, Renata F. da Castello Branco, Luiz R. R. Degrave, Wim M. Lima, Leila Mendonça |
| author_role |
author |
| author2 |
Kalume, Dario E. Correa, Paloma R. Gomes, Leonardo H. F. Pereira, Melissa P. Silva, Renata F. da Castello Branco, Luiz R. R. Degrave, Wim M. Lima, Leila Mendonça |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Pinho, Marcia Berrêdo Kalume, Dario E. Correa, Paloma R. Gomes, Leonardo H. F. Pereira, Melissa P. Silva, Renata F. da Castello Branco, Luiz R. R. Degrave, Wim M. Lima, Leila Mendonça |
| dc.subject.other.pt_BR.fl_str_mv |
Mycobacterium bovis BCG Moreu Mycobacterium bovis BCG Pasteur Tuberculose Perfil proteômico Vacina brasileira |
| topic |
Mycobacterium bovis BCG Moreu Mycobacterium bovis BCG Pasteur Tuberculose Perfil proteômico Vacina brasileira M. bovis BCG Pasteur Tuberculosis Brazilian vaccine Mycobacterium bovis BCG Moreau Proteomic profile Bacille Calmette-Guerin |
| dc.subject.en.pt_BR.fl_str_mv |
M. bovis BCG Pasteur Tuberculosis Brazilian vaccine Mycobacterium bovis BCG Moreau Proteomic profile Bacille Calmette-Guerin |
| description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática.. Rio de Janeiro, RJ. Brasil. |
| publishDate |
2011 |
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2011 |
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2018-04-19T13:40:05Z |
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2018-04-19T13:40:05Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.citation.fl_str_mv |
PINHO, Márcia Berrêdo; et al. Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur. BMC Microbiology, v.11:80, 12p, 2011. |
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https://www.arca.fiocruz.br/handle/icict/25948 |
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1471-2180 |
| dc.identifier.doi.none.fl_str_mv |
10.1186/1471-2180-11-80 |
| identifier_str_mv |
PINHO, Márcia Berrêdo; et al. Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur. BMC Microbiology, v.11:80, 12p, 2011. 1471-2180 10.1186/1471-2180-11-80 |
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eng |
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BioMed Central |
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BioMed Central |
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