Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.

Detalhes bibliográficos
Autor(a) principal: Pinto, Maria E.A.
Data de Publicação: 2017
Outros Autores: Araújo, Sthéfane Gomes, Morais, Marcela I., Sá, Nívea P., Lima, Caroline M., Rosa, Carlos A., Siqueira Filho, Ezequias Pessoa de, Johann, Susana, Lima, Luciana A.R.S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/25468
Resumo: 2020-01-01
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spelling Pinto, Maria E.A.Araújo, Sthéfane GomesMorais, Marcela I.Sá, Nívea P.Lima, Caroline M.Rosa, Carlos A.Siqueira Filho, Ezequias Pessoa deJohann, SusanaLima, Luciana A.R.S.2018-03-22T15:56:44Z2018-03-22T15:56:44Z2017PINTO, Maria E.A. et al. Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. An. Acad. Bras. Ciênc., v. 89, n. 3, p. 1671-1681, 2017.0001-3765https://www.arca.fiocruz.br/handle/icict/2546810.1590/0001-3765201720160908engAcademia Brasileira de Ciênciasanti fungosantioxidantesoleos vegetaisantifungalantioxidantfatty acid methyl estersvegetable oilsAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-01-01Universidade Federal de São João Del Rei. Divinópolis, MG, BrazilUniversidade Federal de São João Del Rei. Divinópolis, MG, BrazilUniversidade Federal de São João Del Rei. Divinópolis, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Instituto Rene Rachou. René Rachou. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, BrazilUniversidade Federal de São João Del Rei. Divinópolis, MG, BrazilFatty acid methyl esters (FAMEs) were obtained from vegetable oils of soybean, corn and sunflower. The current study was focused on evaluating the antifungal activity of FAMEs mainly against Paracoccidioides spp., as well as testing the interaction of these compounds with commercial antifungal drugs and also their antioxidant potential. FAMEs presented small IC50 values (1.86-9.42 μg/mL). All three FAMEs tested showed antifungal activity against isolates of Paracoccidioides spp. with MIC values ranging from 15.6-500 µg/mL. Sunflower FAMEs exhibited antifungal activity that extended also to other genera, with an MIC of 15.6 μg/mL against Candida glabrata and C. krusei and 31.2 μg/mL against C. parapsilosis. FAMEs exhibited a synergetic effect with itraconazole. The antifungal activity of the FAMEs against isolates of Paracoccidioides spp. is likely due to the presence of methyl linoleate, the major compound present in all three FAMEs. The results obtained indicate the potential of FAMEs as sources for antifungal and antioxidant activity.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/25468/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.pdfAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.pdfapplication/pdf632690https://www.arca.fiocruz.br/bitstream/icict/25468/2/Antifungal%20and%20antioxidant%20activity%20of%20fatty%20acid%20methyl%20esters%20from%20vegetable%20oils.pdf042a1b2676ed88146463bd92d80209e8MD52TEXTAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.pdf.txtAntifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
title Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
spellingShingle Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
Pinto, Maria E.A.
anti fungos
antioxidantes
oleos vegetais
antifungal
antioxidant
fatty acid methyl esters
vegetable oils
title_short Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
title_full Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
title_fullStr Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
title_full_unstemmed Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
title_sort Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils.
author Pinto, Maria E.A.
author_facet Pinto, Maria E.A.
Araújo, Sthéfane Gomes
Morais, Marcela I.
Sá, Nívea P.
Lima, Caroline M.
Rosa, Carlos A.
Siqueira Filho, Ezequias Pessoa de
Johann, Susana
Lima, Luciana A.R.S.
author_role author
author2 Araújo, Sthéfane Gomes
Morais, Marcela I.
Sá, Nívea P.
Lima, Caroline M.
Rosa, Carlos A.
Siqueira Filho, Ezequias Pessoa de
Johann, Susana
Lima, Luciana A.R.S.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pinto, Maria E.A.
Araújo, Sthéfane Gomes
Morais, Marcela I.
Sá, Nívea P.
Lima, Caroline M.
Rosa, Carlos A.
Siqueira Filho, Ezequias Pessoa de
Johann, Susana
Lima, Luciana A.R.S.
dc.subject.other.pt_BR.fl_str_mv anti fungos
antioxidantes
oleos vegetais
topic anti fungos
antioxidantes
oleos vegetais
antifungal
antioxidant
fatty acid methyl esters
vegetable oils
dc.subject.en.pt_BR.fl_str_mv antifungal
antioxidant
fatty acid methyl esters
vegetable oils
description 2020-01-01
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2018-03-22T15:56:44Z
dc.date.available.fl_str_mv 2018-03-22T15:56:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv PINTO, Maria E.A. et al. Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. An. Acad. Bras. Ciênc., v. 89, n. 3, p. 1671-1681, 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/25468
dc.identifier.issn.pt_BR.fl_str_mv 0001-3765
dc.identifier.doi.none.fl_str_mv 10.1590/0001-3765201720160908
identifier_str_mv PINTO, Maria E.A. et al. Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils. An. Acad. Bras. Ciênc., v. 89, n. 3, p. 1671-1681, 2017.
0001-3765
10.1590/0001-3765201720160908
url https://www.arca.fiocruz.br/handle/icict/25468
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/25468/1/license.txt
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