Bone disease in HIV infection: a practical review and recommendations for HIV care providers

Detalhes bibliográficos
Autor(a) principal: McComsey, Grace A
Data de Publicação: 2010
Outros Autores: Tebas, Pablo, Shane, Elizabeth, Yin, Michael T, Overton, E Turner, Huang, Jeannie S, Aldrovandi, Grace M, Cardoso, Sandra W, Santana, Jorge L, Brown, Todd T
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/30274
Resumo: Case Western Reserve University. Departments of Pediatrics and Medicine. Cleveland, Ohio, USA.
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spelling McComsey, Grace ATebas, PabloShane, ElizabethYin, Michael TOverton, E TurnerHuang, Jeannie SAldrovandi, Grace MCardoso, Sandra WSantana, Jorge LBrown, Todd T2018-11-28T13:31:53Z2018-11-28T13:31:53Z2010MCCOMSEY, G. A. et al. Bone disease in HIV infection: a practical review and recommendations for HIV care providers. Clinical infectious diseases, v. 51, n. 8, p. 937-946, 2010.1058-4838https://www.arca.fiocruz.br/handle/icict/3027410.1086/656412engBone disease in HIV infection: a practical review and recommendations for HIV care providersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCase Western Reserve University. Departments of Pediatrics and Medicine. Cleveland, Ohio, USA.University of Pennsylvania. Department of Medicine. Philadelphia, USA.Columbia University. Department of Medicine. College of Physicians and Surgeons. New York, NY, USA.Columbia University. Department of Medicine. College of Physicians and Surgeons. New York, NY, USA.Washington University School of Medicine. Department of Medicine. St. Louis, Missouri, USA.University of California at San Diego. Department of Pediatrics. San Diego, USA.Childrens Hospital Los Angeles. Department of Pediatrics. Los Angeles, California, USA.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.University of Puerto Rico. School of Medicine. Department of Medicine. San Juan, Puerto Rico.Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, Maryland, USA.Low bone mineral density (BMD) is prevalent in human immunodeficiency virus (HIV)-infected subjects. Initiation of antiretroviral therapy is associated with a 2%-6% decrease in BMD over the first 2 years, a decrease that is similar in magnitude to that sustained during the first 2 years of menopause. Recent studies have also described increased fracture rates in the HIV-infected population. The causes of low BMD in individuals with HIV infection appear to be multifactorial and likely represent a complex interaction between HIV infection, traditional osteoporosis risk factors, and antiretroviral-related factors. In this review, we make the point that HIV infection should be considered as a risk factor for bone disease. We recommend screening patients with fragility fractures, all HIV-infected post-menopausal women, and all HIV-infected men ⩾50 years of age. We also discuss the importance of considering secondary causes of osteoporosis. Finally, we discuss treatment of the more severe cases of bone disease, while outlining the caveats and gaps in our knowledge.Anti-HIV AgentsBone DiseasesBone DensityHIV Infectionsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/30274/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALBone Disease in HIV Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdfBone Disease in HIV Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdfapplication/pdf572802https://www.arca.fiocruz.br/bitstream/icict/30274/2/Bone%20Disease%20in%20HIV%20Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdf05474924ddd2180c4e25c02e527947ddMD52TEXTBone Disease in HIV Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdf.txtBone Disease in HIV Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Bone disease in HIV infection: a practical review and recommendations for HIV care providers
title Bone disease in HIV infection: a practical review and recommendations for HIV care providers
spellingShingle Bone disease in HIV infection: a practical review and recommendations for HIV care providers
McComsey, Grace A
Anti-HIV Agents
Bone Diseases
Bone Density
HIV Infections
title_short Bone disease in HIV infection: a practical review and recommendations for HIV care providers
title_full Bone disease in HIV infection: a practical review and recommendations for HIV care providers
title_fullStr Bone disease in HIV infection: a practical review and recommendations for HIV care providers
title_full_unstemmed Bone disease in HIV infection: a practical review and recommendations for HIV care providers
title_sort Bone disease in HIV infection: a practical review and recommendations for HIV care providers
author McComsey, Grace A
author_facet McComsey, Grace A
Tebas, Pablo
Shane, Elizabeth
Yin, Michael T
Overton, E Turner
Huang, Jeannie S
Aldrovandi, Grace M
Cardoso, Sandra W
Santana, Jorge L
Brown, Todd T
author_role author
author2 Tebas, Pablo
Shane, Elizabeth
Yin, Michael T
Overton, E Turner
Huang, Jeannie S
Aldrovandi, Grace M
Cardoso, Sandra W
Santana, Jorge L
Brown, Todd T
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv McComsey, Grace A
Tebas, Pablo
Shane, Elizabeth
Yin, Michael T
Overton, E Turner
Huang, Jeannie S
Aldrovandi, Grace M
Cardoso, Sandra W
Santana, Jorge L
Brown, Todd T
dc.subject.en.pt_BR.fl_str_mv Anti-HIV Agents
Bone Diseases
Bone Density
HIV Infections
topic Anti-HIV Agents
Bone Diseases
Bone Density
HIV Infections
description Case Western Reserve University. Departments of Pediatrics and Medicine. Cleveland, Ohio, USA.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2018-11-28T13:31:53Z
dc.date.available.fl_str_mv 2018-11-28T13:31:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv MCCOMSEY, G. A. et al. Bone disease in HIV infection: a practical review and recommendations for HIV care providers. Clinical infectious diseases, v. 51, n. 8, p. 937-946, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/30274
dc.identifier.issn.pt_BR.fl_str_mv 1058-4838
dc.identifier.doi.none.fl_str_mv 10.1086/656412
identifier_str_mv MCCOMSEY, G. A. et al. Bone disease in HIV infection: a practical review and recommendations for HIV care providers. Clinical infectious diseases, v. 51, n. 8, p. 937-946, 2010.
1058-4838
10.1086/656412
url https://www.arca.fiocruz.br/handle/icict/30274
dc.language.iso.fl_str_mv eng
language eng
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