Bone disease in HIV infection: a practical review and recommendations for HIV care providers
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/30274 |
Resumo: | Case Western Reserve University. Departments of Pediatrics and Medicine. Cleveland, Ohio, USA. |
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McComsey, Grace ATebas, PabloShane, ElizabethYin, Michael TOverton, E TurnerHuang, Jeannie SAldrovandi, Grace MCardoso, Sandra WSantana, Jorge LBrown, Todd T2018-11-28T13:31:53Z2018-11-28T13:31:53Z2010MCCOMSEY, G. A. et al. Bone disease in HIV infection: a practical review and recommendations for HIV care providers. Clinical infectious diseases, v. 51, n. 8, p. 937-946, 2010.1058-4838https://www.arca.fiocruz.br/handle/icict/3027410.1086/656412engBone disease in HIV infection: a practical review and recommendations for HIV care providersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCase Western Reserve University. Departments of Pediatrics and Medicine. Cleveland, Ohio, USA.University of Pennsylvania. Department of Medicine. Philadelphia, USA.Columbia University. Department of Medicine. College of Physicians and Surgeons. New York, NY, USA.Columbia University. Department of Medicine. College of Physicians and Surgeons. New York, NY, USA.Washington University School of Medicine. Department of Medicine. St. Louis, Missouri, USA.University of California at San Diego. Department of Pediatrics. San Diego, USA.Childrens Hospital Los Angeles. Department of Pediatrics. Los Angeles, California, USA.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.University of Puerto Rico. School of Medicine. Department of Medicine. San Juan, Puerto Rico.Johns Hopkins University. School of Medicine. Department of Medicine. Baltimore, Maryland, USA.Low bone mineral density (BMD) is prevalent in human immunodeficiency virus (HIV)-infected subjects. Initiation of antiretroviral therapy is associated with a 2%-6% decrease in BMD over the first 2 years, a decrease that is similar in magnitude to that sustained during the first 2 years of menopause. Recent studies have also described increased fracture rates in the HIV-infected population. The causes of low BMD in individuals with HIV infection appear to be multifactorial and likely represent a complex interaction between HIV infection, traditional osteoporosis risk factors, and antiretroviral-related factors. In this review, we make the point that HIV infection should be considered as a risk factor for bone disease. We recommend screening patients with fragility fractures, all HIV-infected post-menopausal women, and all HIV-infected men ⩾50 years of age. We also discuss the importance of considering secondary causes of osteoporosis. Finally, we discuss treatment of the more severe cases of bone disease, while outlining the caveats and gaps in our knowledge.Anti-HIV AgentsBone DiseasesBone DensityHIV Infectionsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/30274/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALBone Disease in HIV Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdfBone Disease in HIV Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdfapplication/pdf572802https://www.arca.fiocruz.br/bitstream/icict/30274/2/Bone%20Disease%20in%20HIV%20Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdf05474924ddd2180c4e25c02e527947ddMD52TEXTBone Disease in HIV Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdf.txtBone Disease in HIV Infection_Sandra_Wagner_INI_Lapclin-AIDS_2010.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv |
Bone disease in HIV infection: a practical review and recommendations for HIV care providers |
title |
Bone disease in HIV infection: a practical review and recommendations for HIV care providers |
spellingShingle |
Bone disease in HIV infection: a practical review and recommendations for HIV care providers McComsey, Grace A Anti-HIV Agents Bone Diseases Bone Density HIV Infections |
title_short |
Bone disease in HIV infection: a practical review and recommendations for HIV care providers |
title_full |
Bone disease in HIV infection: a practical review and recommendations for HIV care providers |
title_fullStr |
Bone disease in HIV infection: a practical review and recommendations for HIV care providers |
title_full_unstemmed |
Bone disease in HIV infection: a practical review and recommendations for HIV care providers |
title_sort |
Bone disease in HIV infection: a practical review and recommendations for HIV care providers |
author |
McComsey, Grace A |
author_facet |
McComsey, Grace A Tebas, Pablo Shane, Elizabeth Yin, Michael T Overton, E Turner Huang, Jeannie S Aldrovandi, Grace M Cardoso, Sandra W Santana, Jorge L Brown, Todd T |
author_role |
author |
author2 |
Tebas, Pablo Shane, Elizabeth Yin, Michael T Overton, E Turner Huang, Jeannie S Aldrovandi, Grace M Cardoso, Sandra W Santana, Jorge L Brown, Todd T |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
McComsey, Grace A Tebas, Pablo Shane, Elizabeth Yin, Michael T Overton, E Turner Huang, Jeannie S Aldrovandi, Grace M Cardoso, Sandra W Santana, Jorge L Brown, Todd T |
dc.subject.en.pt_BR.fl_str_mv |
Anti-HIV Agents Bone Diseases Bone Density HIV Infections |
topic |
Anti-HIV Agents Bone Diseases Bone Density HIV Infections |
description |
Case Western Reserve University. Departments of Pediatrics and Medicine. Cleveland, Ohio, USA. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010 |
dc.date.accessioned.fl_str_mv |
2018-11-28T13:31:53Z |
dc.date.available.fl_str_mv |
2018-11-28T13:31:53Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MCCOMSEY, G. A. et al. Bone disease in HIV infection: a practical review and recommendations for HIV care providers. Clinical infectious diseases, v. 51, n. 8, p. 937-946, 2010. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/30274 |
dc.identifier.issn.pt_BR.fl_str_mv |
1058-4838 |
dc.identifier.doi.none.fl_str_mv |
10.1086/656412 |
identifier_str_mv |
MCCOMSEY, G. A. et al. Bone disease in HIV infection: a practical review and recommendations for HIV care providers. Clinical infectious diseases, v. 51, n. 8, p. 937-946, 2010. 1058-4838 10.1086/656412 |
url |
https://www.arca.fiocruz.br/handle/icict/30274 |
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eng |
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