Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study

Detalhes bibliográficos
Autor(a) principal: Ferreira, Isabel C.F.R.
Data de Publicação: 2004
Outros Autores: Calhelha, Ricardo C., Estevinho, Leticia M., Queiroz, Maria João R.P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/821
Resumo: Gram positive (Bacillus cereus, B. subtilis), Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria, and Candida albicans as a representative of fungi were used for screening the in vitro antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[ b]thiophene series bearing different substituents, synthesized by us using the palladium-catalyzed C–N coupling methodology. The minimal inhibitory concentration (MIC) and structure–activity relationships (SARs) were evaluated.
id RCAP_51dd8dae7378b5141d118c5ef6fdf2cd
oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/821
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str
spelling Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation studyDiarylaminesAntimicrobial activitySARBenzothiophenesGram positive (Bacillus cereus, B. subtilis), Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria, and Candida albicans as a representative of fungi were used for screening the in vitro antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[ b]thiophene series bearing different substituents, synthesized by us using the palladium-catalyzed C–N coupling methodology. The minimal inhibitory concentration (MIC) and structure–activity relationships (SARs) were evaluated.ElsevierBiblioteca Digital do IPBFerreira, Isabel C.F.R.Calhelha, Ricardo C.Estevinho, Leticia M.Queiroz, Maria João R.P.2008-09-12T13:33:00Z20042004-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/821engFerreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Leticia M.; Queiroz, Maria João R.P. (2004). Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study. Bioorganic & Medicinal Chemistry Letters. ISSN 0960-894X. 14:23, p. 5831-58330960-894X10.1016/j.bmcl.2004.09.038info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-01-16T12:04:48ZPortal AgregadorONG
dc.title.none.fl_str_mv Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study
title Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study
spellingShingle Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study
Ferreira, Isabel C.F.R.
Diarylamines
Antimicrobial activity
SAR
Benzothiophenes
title_short Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study
title_full Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study
title_fullStr Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study
title_full_unstemmed Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study
title_sort Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study
author Ferreira, Isabel C.F.R.
author_facet Ferreira, Isabel C.F.R.
Calhelha, Ricardo C.
Estevinho, Leticia M.
Queiroz, Maria João R.P.
author_role author
author2 Calhelha, Ricardo C.
Estevinho, Leticia M.
Queiroz, Maria João R.P.
author2_role author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Ferreira, Isabel C.F.R.
Calhelha, Ricardo C.
Estevinho, Leticia M.
Queiroz, Maria João R.P.
dc.subject.por.fl_str_mv Diarylamines
Antimicrobial activity
SAR
Benzothiophenes
topic Diarylamines
Antimicrobial activity
SAR
Benzothiophenes
description Gram positive (Bacillus cereus, B. subtilis), Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria, and Candida albicans as a representative of fungi were used for screening the in vitro antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[ b]thiophene series bearing different substituents, synthesized by us using the palladium-catalyzed C–N coupling methodology. The minimal inhibitory concentration (MIC) and structure–activity relationships (SARs) were evaluated.
publishDate 2004
dc.date.none.fl_str_mv 2004
2004-01-01T00:00:00Z
2008-09-12T13:33:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/821
url http://hdl.handle.net/10198/821
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Leticia M.; Queiroz, Maria João R.P. (2004). Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study. Bioorganic & Medicinal Chemistry Letters. ISSN 0960-894X. 14:23, p. 5831-5833
0960-894X
10.1016/j.bmcl.2004.09.038
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1777301782952673280

Registros relacionados