Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power

Detalhes bibliográficos
Autor(a) principal: Ferreira, Isabel C.F.R.
Data de Publicação: 2006
Outros Autores: Queiroz, Maria João R.P., Vilas-Boas, Miguel, Estevinho, Leticia M., Begouin, Agathe, Kirsch, Gilbert
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/825
Resumo: The antioxidant properties of substituted diarylamines in the benzo[b]thiophene series were evaluated by their reducing power and free radical scavenging activity. The results were compared with those of standards: acid ascorbic for the first method and BHA and BHT for the second. For both methods it was possible to establish some structure–activity relationships (SARs) based on the position of the arylamination on the benzo[b]thiophene moiety, the presence of different substituents on the phenyl ring (F, 1 or 2 OMe) and on the thiophene ring (H, CO2Et, CO2H).
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spelling Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing powerDiarylaminesBenzothiophenesAntioxidant activityStructure–activity relationshipsThe antioxidant properties of substituted diarylamines in the benzo[b]thiophene series were evaluated by their reducing power and free radical scavenging activity. The results were compared with those of standards: acid ascorbic for the first method and BHA and BHT for the second. For both methods it was possible to establish some structure–activity relationships (SARs) based on the position of the arylamination on the benzo[b]thiophene moiety, the presence of different substituents on the phenyl ring (F, 1 or 2 OMe) and on the thiophene ring (H, CO2Et, CO2H).ElsevierBiblioteca Digital do IPBFerreira, Isabel C.F.R.Queiroz, Maria João R.P.Vilas-Boas, MiguelEstevinho, Leticia M.Begouin, AgatheKirsch, Gilbert2008-09-12T14:53:06Z20062006-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/825engFerreira, Isabel C.F.R.; Queiroz, Maria João R.P.; Vilas-Boas, Miguel; Estevinho, Leticia M.; Begouin, Agathe; Kirsch, Gilbert (2006). Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power. Bioorganic & Medicinal Chemistry Letters. ISSN 0960-894X. 16:5, p. 1384-13870960-894X10.1016/j.bmcl.2005.11.035info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-01-16T12:04:48ZPortal AgregadorONG
dc.title.none.fl_str_mv Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
title Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
spellingShingle Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
Ferreira, Isabel C.F.R.
Diarylamines
Benzothiophenes
Antioxidant activity
Structure–activity relationships
title_short Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
title_full Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
title_fullStr Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
title_full_unstemmed Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
title_sort Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power
author Ferreira, Isabel C.F.R.
author_facet Ferreira, Isabel C.F.R.
Queiroz, Maria João R.P.
Vilas-Boas, Miguel
Estevinho, Leticia M.
Begouin, Agathe
Kirsch, Gilbert
author_role author
author2 Queiroz, Maria João R.P.
Vilas-Boas, Miguel
Estevinho, Leticia M.
Begouin, Agathe
Kirsch, Gilbert
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Ferreira, Isabel C.F.R.
Queiroz, Maria João R.P.
Vilas-Boas, Miguel
Estevinho, Leticia M.
Begouin, Agathe
Kirsch, Gilbert
dc.subject.por.fl_str_mv Diarylamines
Benzothiophenes
Antioxidant activity
Structure–activity relationships
topic Diarylamines
Benzothiophenes
Antioxidant activity
Structure–activity relationships
description The antioxidant properties of substituted diarylamines in the benzo[b]thiophene series were evaluated by their reducing power and free radical scavenging activity. The results were compared with those of standards: acid ascorbic for the first method and BHA and BHT for the second. For both methods it was possible to establish some structure–activity relationships (SARs) based on the position of the arylamination on the benzo[b]thiophene moiety, the presence of different substituents on the phenyl ring (F, 1 or 2 OMe) and on the thiophene ring (H, CO2Et, CO2H).
publishDate 2006
dc.date.none.fl_str_mv 2006
2006-01-01T00:00:00Z
2008-09-12T14:53:06Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/825
url http://hdl.handle.net/10198/825
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ferreira, Isabel C.F.R.; Queiroz, Maria João R.P.; Vilas-Boas, Miguel; Estevinho, Leticia M.; Begouin, Agathe; Kirsch, Gilbert (2006). Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power. Bioorganic & Medicinal Chemistry Letters. ISSN 0960-894X. 16:5, p. 1384-1387
0960-894X
10.1016/j.bmcl.2005.11.035
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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