Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://repositorio.unifesp.br/handle/11600/55011 http://dx.doi.org/10.1167/iovs.16-20969 |
Resumo: | PURPOSE. The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). METHODS. Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 x 3-and 6 x 6-mm(2) scans were obtained on both instruments. The 3 x 3-mm(2) SS-OCTA scans consisted of 300 A-scans per B-scan at 300 B-scan positions, and the SD-OCTA scans consisted of 245 A-scans at 245 B-scan positions. The 6 x 6-mm(2) SS-OCTA scans consisted of 420 A-scans per B-scan at 420 B-scan positions, and the SD-OCTA scans consisted of 350 A-scans and 350 B-scan positions. B-scans were repeated four times at each position in the 3 x 3-mm(2) scans and twice in the 6 x 6-mm(2) scans. Choroidal neovascularization was excluded if not fully contained within the 3 x 3-mm(2) scans. The same algorithm was used to detect CNV on both instruments. Two graders outlined the CNV, and the lesion areas were compared between instruments. RESULTS. Twenty-seven consecutive eyes from 23 patients were analyzed. For the 3 x 3-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.17 and 1.01 mm(2), respectively (P = 0.047). For the 6 x 6-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.24 and 0.74 mm(2) (P = 0.003). CONCLUSIONS. The areas of CNV tended to be larger when imaged with SS-OCTA than with SD-OCTA, and this difference was greater for the 6 x 6-mm(2) scans. |
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Miller, Andrew R.Roisman, Luiz [UNIFESP]Zhang, QinqinZheng, FangDias, Joao Rafael de OliveiraYehoshua, ZoharSchaal, Karen B.Feuer, WilliamGregori, GiovanniChu, ZhongdiChen, Chieh-LiKubach, SophieAn, LinStetson, Paul F.Durbin, Mary K.Wang, Ruikang K.Rosenfeld, Philip J.2020-07-17T14:02:46Z2020-07-17T14:02:46Z2017Investigative Ophthalmology & Visual Science. Rockville, v. 58, n. 3, p. 1499-1505, 2017.0146-0404https://repositorio.unifesp.br/handle/11600/55011http://dx.doi.org/10.1167/iovs.16-20969WOS000398089000018.pdf10.1167/iovs.16-20969WOS:000398089000018PURPOSE. The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). METHODS. Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 x 3-and 6 x 6-mm(2) scans were obtained on both instruments. The 3 x 3-mm(2) SS-OCTA scans consisted of 300 A-scans per B-scan at 300 B-scan positions, and the SD-OCTA scans consisted of 245 A-scans at 245 B-scan positions. The 6 x 6-mm(2) SS-OCTA scans consisted of 420 A-scans per B-scan at 420 B-scan positions, and the SD-OCTA scans consisted of 350 A-scans and 350 B-scan positions. B-scans were repeated four times at each position in the 3 x 3-mm(2) scans and twice in the 6 x 6-mm(2) scans. Choroidal neovascularization was excluded if not fully contained within the 3 x 3-mm(2) scans. The same algorithm was used to detect CNV on both instruments. Two graders outlined the CNV, and the lesion areas were compared between instruments. RESULTS. Twenty-seven consecutive eyes from 23 patients were analyzed. For the 3 x 3-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.17 and 1.01 mm(2), respectively (P = 0.047). For the 6 x 6-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.24 and 0.74 mm(2) (P = 0.003). CONCLUSIONS. The areas of CNV tended to be larger when imaged with SS-OCTA than with SD-OCTA, and this difference was greater for the 6 x 6-mm(2) scans.Carl Zeiss Meditec, Inc.National Eye InstituteResearch to Prevent Blindness, Inc. (New York, NY)National Eye Institute Center Core GrantCAPES Foundation, Ministry of Education of Brazil (Brasilia, Brazil)German Research FoundationUniv Miami, Miller Sch Med, Bascom Palmer Eye Inst, Dept Ophthalmol, Miami, FL 33136 USAUniv Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, BrazilUniv Washington, Dept Bioengn, Seattle, WA 98195 USACarl Zeiss Meditec Inc, Adv Dev, Dublin, CA USAUniv Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, BrazilNational Eye Institute: R01EY024158National Eye Institute Center Core Grant: P30EY014801German Research Foundation: SCHA 1869/1-1Web of Science1499-1505engAssoc Research Vision Ophthalmology IncInvestigative Ophthalmology & Visual Scienceoptical coherence tomography angiographyOCTAswept-source OCTAspectral-domain OCTAneovascular AMDchoroidal neovascularizationComparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularizationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRockville583info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000398089000018.pdfapplication/pdf1256897${dspace.ui.url}/bitstream/11600/55011/1/WOS000398089000018.pdf9424b79da5f6e27e267833a0d466e80bMD51open accessTEXTWOS000398089000018.pdf.txtWOS000398089000018.pdf.txtExtracted texttext/plain36007${dspace.ui.url}/bitstream/11600/55011/2/WOS000398089000018.pdf.txtb4e76b6351f4bd2e463f7257d3e91f2eMD52open accessTHUMBNAILWOS000398089000018.pdf.jpgWOS000398089000018.pdf.jpgIM Thumbnailimage/jpeg7697${dspace.ui.url}/bitstream/11600/55011/4/WOS000398089000018.pdf.jpg8d546f37866cc3281942dc953e5669adMD54open access11600/550112022-08-01 05:08:29.55open accessoai:repositorio.unifesp.br:11600/55011Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:07:14.806078Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization |
title |
Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization |
spellingShingle |
Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization Miller, Andrew R. optical coherence tomography angiography OCTA swept-source OCTA spectral-domain OCTA neovascular AMD choroidal neovascularization |
title_short |
Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization |
title_full |
Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization |
title_fullStr |
Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization |
title_full_unstemmed |
Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization |
title_sort |
Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization |
author |
Miller, Andrew R. |
author_facet |
Miller, Andrew R. Roisman, Luiz [UNIFESP] Zhang, Qinqin Zheng, Fang Dias, Joao Rafael de Oliveira Yehoshua, Zohar Schaal, Karen B. Feuer, William Gregori, Giovanni Chu, Zhongdi Chen, Chieh-Li Kubach, Sophie An, Lin Stetson, Paul F. Durbin, Mary K. Wang, Ruikang K. Rosenfeld, Philip J. |
author_role |
author |
author2 |
Roisman, Luiz [UNIFESP] Zhang, Qinqin Zheng, Fang Dias, Joao Rafael de Oliveira Yehoshua, Zohar Schaal, Karen B. Feuer, William Gregori, Giovanni Chu, Zhongdi Chen, Chieh-Li Kubach, Sophie An, Lin Stetson, Paul F. Durbin, Mary K. Wang, Ruikang K. Rosenfeld, Philip J. |
author2_role |
author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Miller, Andrew R. Roisman, Luiz [UNIFESP] Zhang, Qinqin Zheng, Fang Dias, Joao Rafael de Oliveira Yehoshua, Zohar Schaal, Karen B. Feuer, William Gregori, Giovanni Chu, Zhongdi Chen, Chieh-Li Kubach, Sophie An, Lin Stetson, Paul F. Durbin, Mary K. Wang, Ruikang K. Rosenfeld, Philip J. |
dc.subject.eng.fl_str_mv |
optical coherence tomography angiography OCTA swept-source OCTA spectral-domain OCTA neovascular AMD choroidal neovascularization |
topic |
optical coherence tomography angiography OCTA swept-source OCTA spectral-domain OCTA neovascular AMD choroidal neovascularization |
description |
PURPOSE. The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). METHODS. Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 x 3-and 6 x 6-mm(2) scans were obtained on both instruments. The 3 x 3-mm(2) SS-OCTA scans consisted of 300 A-scans per B-scan at 300 B-scan positions, and the SD-OCTA scans consisted of 245 A-scans at 245 B-scan positions. The 6 x 6-mm(2) SS-OCTA scans consisted of 420 A-scans per B-scan at 420 B-scan positions, and the SD-OCTA scans consisted of 350 A-scans and 350 B-scan positions. B-scans were repeated four times at each position in the 3 x 3-mm(2) scans and twice in the 6 x 6-mm(2) scans. Choroidal neovascularization was excluded if not fully contained within the 3 x 3-mm(2) scans. The same algorithm was used to detect CNV on both instruments. Two graders outlined the CNV, and the lesion areas were compared between instruments. RESULTS. Twenty-seven consecutive eyes from 23 patients were analyzed. For the 3 x 3-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.17 and 1.01 mm(2), respectively (P = 0.047). For the 6 x 6-mm(2) scans, the mean lesion areas for the SS-OCTA and SD-OCTA instruments were 1.24 and 0.74 mm(2) (P = 0.003). CONCLUSIONS. The areas of CNV tended to be larger when imaged with SS-OCTA than with SD-OCTA, and this difference was greater for the 6 x 6-mm(2) scans. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2020-07-17T14:02:46Z |
dc.date.available.fl_str_mv |
2020-07-17T14:02:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Investigative Ophthalmology & Visual Science. Rockville, v. 58, n. 3, p. 1499-1505, 2017. |
dc.identifier.uri.fl_str_mv |
https://repositorio.unifesp.br/handle/11600/55011 http://dx.doi.org/10.1167/iovs.16-20969 |
dc.identifier.issn.none.fl_str_mv |
0146-0404 |
dc.identifier.file.none.fl_str_mv |
WOS000398089000018.pdf |
dc.identifier.doi.none.fl_str_mv |
10.1167/iovs.16-20969 |
dc.identifier.wos.none.fl_str_mv |
WOS:000398089000018 |
identifier_str_mv |
Investigative Ophthalmology & Visual Science. Rockville, v. 58, n. 3, p. 1499-1505, 2017. 0146-0404 WOS000398089000018.pdf 10.1167/iovs.16-20969 WOS:000398089000018 |
url |
https://repositorio.unifesp.br/handle/11600/55011 http://dx.doi.org/10.1167/iovs.16-20969 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Investigative Ophthalmology & Visual Science |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
1499-1505 |
dc.coverage.none.fl_str_mv |
Rockville |
dc.publisher.none.fl_str_mv |
Assoc Research Vision Ophthalmology Inc |
publisher.none.fl_str_mv |
Assoc Research Vision Ophthalmology Inc |
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reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
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