Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais da Academia Brasileira de Ciências (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602 |
Resumo: | Abstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main constituents; Germacrene D (17.2%), α-pinene (14.8%) and E-caryophyllene (10.8%). The results showed that isoflavone (2000 to 156 μg/mL) and essential oil (5.0 to 1.25%) present antibacterial and antifungal activity against Gram-positive bacteria and filamentous fungi. The isoflavone and the essential oil also presented antioxidant activity in all the tests, mainly on inhibition of the oxidation of β-carotene test concentrations ranging from 60 to 100%. In conclusion, isoflavone and essential oil from M. peruiferum present an antimicrobial alternative against Gram-positive bacteria, especially of the genus Staphylococcus and dermatophyte fungi of the genus Trichophyton, as well as a natural compound antioxidant. |
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Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.fantimicrobial activityantioxidant activityessential oilisoflavoneMyroxylon peruiferumAbstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main constituents; Germacrene D (17.2%), α-pinene (14.8%) and E-caryophyllene (10.8%). The results showed that isoflavone (2000 to 156 μg/mL) and essential oil (5.0 to 1.25%) present antibacterial and antifungal activity against Gram-positive bacteria and filamentous fungi. The isoflavone and the essential oil also presented antioxidant activity in all the tests, mainly on inhibition of the oxidation of β-carotene test concentrations ranging from 60 to 100%. In conclusion, isoflavone and essential oil from M. peruiferum present an antimicrobial alternative against Gram-positive bacteria, especially of the genus Staphylococcus and dermatophyte fungi of the genus Trichophyton, as well as a natural compound antioxidant.Academia Brasileira de Ciências2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602Anais da Academia Brasileira de Ciências v.91 n.2 2019reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765201920180204info:eu-repo/semantics/openAccessPEREIRA,RAFAELPEREIRA,ANNA L.FERREIRA,MARCILIO M.FONTENELLE,RAQUEL O.S.SAKER-SAMPAIO,SILVANASANTOS,HÉLCIO S.BANDEIRA,PAULO N.VASCONCELOS,MAYRON A.QUEIROZ,JOSÉ A.N.BRAZ-FILHO,RAIMUNDOTEIXEIRA,EDSON H.eng2019-04-17T00:00:00Zoai:scielo:S0001-37652019000300602Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2019-04-17T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false |
dc.title.none.fl_str_mv |
Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f |
title |
Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f |
spellingShingle |
Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f PEREIRA,RAFAEL antimicrobial activity antioxidant activity essential oil isoflavone Myroxylon peruiferum |
title_short |
Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f |
title_full |
Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f |
title_fullStr |
Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f |
title_full_unstemmed |
Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f |
title_sort |
Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f |
author |
PEREIRA,RAFAEL |
author_facet |
PEREIRA,RAFAEL PEREIRA,ANNA L. FERREIRA,MARCILIO M. FONTENELLE,RAQUEL O.S. SAKER-SAMPAIO,SILVANA SANTOS,HÉLCIO S. BANDEIRA,PAULO N. VASCONCELOS,MAYRON A. QUEIROZ,JOSÉ A.N. BRAZ-FILHO,RAIMUNDO TEIXEIRA,EDSON H. |
author_role |
author |
author2 |
PEREIRA,ANNA L. FERREIRA,MARCILIO M. FONTENELLE,RAQUEL O.S. SAKER-SAMPAIO,SILVANA SANTOS,HÉLCIO S. BANDEIRA,PAULO N. VASCONCELOS,MAYRON A. QUEIROZ,JOSÉ A.N. BRAZ-FILHO,RAIMUNDO TEIXEIRA,EDSON H. |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
PEREIRA,RAFAEL PEREIRA,ANNA L. FERREIRA,MARCILIO M. FONTENELLE,RAQUEL O.S. SAKER-SAMPAIO,SILVANA SANTOS,HÉLCIO S. BANDEIRA,PAULO N. VASCONCELOS,MAYRON A. QUEIROZ,JOSÉ A.N. BRAZ-FILHO,RAIMUNDO TEIXEIRA,EDSON H. |
dc.subject.por.fl_str_mv |
antimicrobial activity antioxidant activity essential oil isoflavone Myroxylon peruiferum |
topic |
antimicrobial activity antioxidant activity essential oil isoflavone Myroxylon peruiferum |
description |
Abstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main constituents; Germacrene D (17.2%), α-pinene (14.8%) and E-caryophyllene (10.8%). The results showed that isoflavone (2000 to 156 μg/mL) and essential oil (5.0 to 1.25%) present antibacterial and antifungal activity against Gram-positive bacteria and filamentous fungi. The isoflavone and the essential oil also presented antioxidant activity in all the tests, mainly on inhibition of the oxidation of β-carotene test concentrations ranging from 60 to 100%. In conclusion, isoflavone and essential oil from M. peruiferum present an antimicrobial alternative against Gram-positive bacteria, especially of the genus Staphylococcus and dermatophyte fungi of the genus Trichophyton, as well as a natural compound antioxidant. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0001-3765201920180204 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
dc.source.none.fl_str_mv |
Anais da Academia Brasileira de Ciências v.91 n.2 2019 reponame:Anais da Academia Brasileira de Ciências (Online) instname:Academia Brasileira de Ciências (ABC) instacron:ABC |
instname_str |
Academia Brasileira de Ciências (ABC) |
instacron_str |
ABC |
institution |
ABC |
reponame_str |
Anais da Academia Brasileira de Ciências (Online) |
collection |
Anais da Academia Brasileira de Ciências (Online) |
repository.name.fl_str_mv |
Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC) |
repository.mail.fl_str_mv |
||aabc@abc.org.br |
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1754302867315884032 |