Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f

Detalhes bibliográficos
Autor(a) principal: PEREIRA,RAFAEL
Data de Publicação: 2019
Outros Autores: PEREIRA,ANNA L., FERREIRA,MARCILIO M., FONTENELLE,RAQUEL O.S., SAKER-SAMPAIO,SILVANA, SANTOS,HÉLCIO S., BANDEIRA,PAULO N., VASCONCELOS,MAYRON A., QUEIROZ,JOSÉ A.N., BRAZ-FILHO,RAIMUNDO, TEIXEIRA,EDSON H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602
Resumo: Abstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main constituents; Germacrene D (17.2%), α-pinene (14.8%) and E-caryophyllene (10.8%). The results showed that isoflavone (2000 to 156 μg/mL) and essential oil (5.0 to 1.25%) present antibacterial and antifungal activity against Gram-positive bacteria and filamentous fungi. The isoflavone and the essential oil also presented antioxidant activity in all the tests, mainly on inhibition of the oxidation of β-carotene test concentrations ranging from 60 to 100%. In conclusion, isoflavone and essential oil from M. peruiferum present an antimicrobial alternative against Gram-positive bacteria, especially of the genus Staphylococcus and dermatophyte fungi of the genus Trichophyton, as well as a natural compound antioxidant.
id ABC-1_0b1cee98704705ebb236a67a3cb201d3
oai_identifier_str oai:scielo:S0001-37652019000300602
network_acronym_str ABC-1
network_name_str Anais da Academia Brasileira de Ciências (Online)
repository_id_str
spelling Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.fantimicrobial activityantioxidant activityessential oilisoflavoneMyroxylon peruiferumAbstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main constituents; Germacrene D (17.2%), α-pinene (14.8%) and E-caryophyllene (10.8%). The results showed that isoflavone (2000 to 156 μg/mL) and essential oil (5.0 to 1.25%) present antibacterial and antifungal activity against Gram-positive bacteria and filamentous fungi. The isoflavone and the essential oil also presented antioxidant activity in all the tests, mainly on inhibition of the oxidation of β-carotene test concentrations ranging from 60 to 100%. In conclusion, isoflavone and essential oil from M. peruiferum present an antimicrobial alternative against Gram-positive bacteria, especially of the genus Staphylococcus and dermatophyte fungi of the genus Trichophyton, as well as a natural compound antioxidant.Academia Brasileira de Ciências2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602Anais da Academia Brasileira de Ciências v.91 n.2 2019reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765201920180204info:eu-repo/semantics/openAccessPEREIRA,RAFAELPEREIRA,ANNA L.FERREIRA,MARCILIO M.FONTENELLE,RAQUEL O.S.SAKER-SAMPAIO,SILVANASANTOS,HÉLCIO S.BANDEIRA,PAULO N.VASCONCELOS,MAYRON A.QUEIROZ,JOSÉ A.N.BRAZ-FILHO,RAIMUNDOTEIXEIRA,EDSON H.eng2019-04-17T00:00:00Zoai:scielo:S0001-37652019000300602Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2019-04-17T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
title Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
spellingShingle Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
PEREIRA,RAFAEL
antimicrobial activity
antioxidant activity
essential oil
isoflavone
Myroxylon peruiferum
title_short Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
title_full Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
title_fullStr Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
title_full_unstemmed Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
title_sort Evaluation of the antimicrobial and antioxidant activity of 7-hydroxy-4’, 6-dimethoxy-isoflavone and essential oil from Myroxylon peruiferum L.f
author PEREIRA,RAFAEL
author_facet PEREIRA,RAFAEL
PEREIRA,ANNA L.
FERREIRA,MARCILIO M.
FONTENELLE,RAQUEL O.S.
SAKER-SAMPAIO,SILVANA
SANTOS,HÉLCIO S.
BANDEIRA,PAULO N.
VASCONCELOS,MAYRON A.
QUEIROZ,JOSÉ A.N.
BRAZ-FILHO,RAIMUNDO
TEIXEIRA,EDSON H.
author_role author
author2 PEREIRA,ANNA L.
FERREIRA,MARCILIO M.
FONTENELLE,RAQUEL O.S.
SAKER-SAMPAIO,SILVANA
SANTOS,HÉLCIO S.
BANDEIRA,PAULO N.
VASCONCELOS,MAYRON A.
QUEIROZ,JOSÉ A.N.
BRAZ-FILHO,RAIMUNDO
TEIXEIRA,EDSON H.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv PEREIRA,RAFAEL
PEREIRA,ANNA L.
FERREIRA,MARCILIO M.
FONTENELLE,RAQUEL O.S.
SAKER-SAMPAIO,SILVANA
SANTOS,HÉLCIO S.
BANDEIRA,PAULO N.
VASCONCELOS,MAYRON A.
QUEIROZ,JOSÉ A.N.
BRAZ-FILHO,RAIMUNDO
TEIXEIRA,EDSON H.
dc.subject.por.fl_str_mv antimicrobial activity
antioxidant activity
essential oil
isoflavone
Myroxylon peruiferum
topic antimicrobial activity
antioxidant activity
essential oil
isoflavone
Myroxylon peruiferum
description Abstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main constituents; Germacrene D (17.2%), α-pinene (14.8%) and E-caryophyllene (10.8%). The results showed that isoflavone (2000 to 156 μg/mL) and essential oil (5.0 to 1.25%) present antibacterial and antifungal activity against Gram-positive bacteria and filamentous fungi. The isoflavone and the essential oil also presented antioxidant activity in all the tests, mainly on inhibition of the oxidation of β-carotene test concentrations ranging from 60 to 100%. In conclusion, isoflavone and essential oil from M. peruiferum present an antimicrobial alternative against Gram-positive bacteria, especially of the genus Staphylococcus and dermatophyte fungi of the genus Trichophyton, as well as a natural compound antioxidant.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0001-3765201920180204
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.91 n.2 2019
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
instacron:ABC
instname_str Academia Brasileira de Ciências (ABC)
instacron_str ABC
institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
repository.mail.fl_str_mv ||aabc@abc.org.br
_version_ 1754302867315884032