Metabolism and secretory function of white adipose tissue: effect of dietary fat

Detalhes bibliográficos
Autor(a) principal: Nascimento,Cláudia M. Oller do
Data de Publicação: 2009
Outros Autores: Ribeiro,Eliane B., Oyama,Lila M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300010
Resumo: Approximately 40% of the total energy consumed by western populations is represented by lipids, most of them being ingested as triacylglycerols and phospholipids. The focus of this review is to analyze the effect of the type of dietary fat on white adipose tissue metabolism and secretory function, particularly on haptoglobin, TNF-α, plasminogen activator inhibitor-1 and adiponectin secretion. Previous studies have demonstrated that the duration of the exposure to the high-fat feeding, amount of fatty acid present in the diet and the type of fatty acid may or may not have a significant effect on adipose tissue metabolism. However, the long-term or short-term high fat diets, especially rich in saturated fatty acids, probably by activation of toll-like receptors, stimulated the expression of proinflammatory adipokines and inhibited adiponectin expression. Further studies are needed to investigate the cellular mechanisms by which dietary fatty acids affect white adipose tissue metabolism and secretory functions.
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spelling Metabolism and secretory function of white adipose tissue: effect of dietary fatadipokineshigh fat dietsmetabolismwhite adipose tissueApproximately 40% of the total energy consumed by western populations is represented by lipids, most of them being ingested as triacylglycerols and phospholipids. The focus of this review is to analyze the effect of the type of dietary fat on white adipose tissue metabolism and secretory function, particularly on haptoglobin, TNF-α, plasminogen activator inhibitor-1 and adiponectin secretion. Previous studies have demonstrated that the duration of the exposure to the high-fat feeding, amount of fatty acid present in the diet and the type of fatty acid may or may not have a significant effect on adipose tissue metabolism. However, the long-term or short-term high fat diets, especially rich in saturated fatty acids, probably by activation of toll-like receptors, stimulated the expression of proinflammatory adipokines and inhibited adiponectin expression. Further studies are needed to investigate the cellular mechanisms by which dietary fatty acids affect white adipose tissue metabolism and secretory functions.Academia Brasileira de Ciências2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300010Anais da Academia Brasileira de Ciências v.81 n.3 2009reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/S0001-37652009000300010info:eu-repo/semantics/openAccessNascimento,Cláudia M. Oller doRibeiro,Eliane B.Oyama,Lila M.eng2009-08-28T00:00:00Zoai:scielo:S0001-37652009000300010Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2009-08-28T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Metabolism and secretory function of white adipose tissue: effect of dietary fat
title Metabolism and secretory function of white adipose tissue: effect of dietary fat
spellingShingle Metabolism and secretory function of white adipose tissue: effect of dietary fat
Nascimento,Cláudia M. Oller do
adipokines
high fat diets
metabolism
white adipose tissue
title_short Metabolism and secretory function of white adipose tissue: effect of dietary fat
title_full Metabolism and secretory function of white adipose tissue: effect of dietary fat
title_fullStr Metabolism and secretory function of white adipose tissue: effect of dietary fat
title_full_unstemmed Metabolism and secretory function of white adipose tissue: effect of dietary fat
title_sort Metabolism and secretory function of white adipose tissue: effect of dietary fat
author Nascimento,Cláudia M. Oller do
author_facet Nascimento,Cláudia M. Oller do
Ribeiro,Eliane B.
Oyama,Lila M.
author_role author
author2 Ribeiro,Eliane B.
Oyama,Lila M.
author2_role author
author
dc.contributor.author.fl_str_mv Nascimento,Cláudia M. Oller do
Ribeiro,Eliane B.
Oyama,Lila M.
dc.subject.por.fl_str_mv adipokines
high fat diets
metabolism
white adipose tissue
topic adipokines
high fat diets
metabolism
white adipose tissue
description Approximately 40% of the total energy consumed by western populations is represented by lipids, most of them being ingested as triacylglycerols and phospholipids. The focus of this review is to analyze the effect of the type of dietary fat on white adipose tissue metabolism and secretory function, particularly on haptoglobin, TNF-α, plasminogen activator inhibitor-1 and adiponectin secretion. Previous studies have demonstrated that the duration of the exposure to the high-fat feeding, amount of fatty acid present in the diet and the type of fatty acid may or may not have a significant effect on adipose tissue metabolism. However, the long-term or short-term high fat diets, especially rich in saturated fatty acids, probably by activation of toll-like receptors, stimulated the expression of proinflammatory adipokines and inhibited adiponectin expression. Further studies are needed to investigate the cellular mechanisms by which dietary fatty acids affect white adipose tissue metabolism and secretory functions.
publishDate 2009
dc.date.none.fl_str_mv 2009-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0001-37652009000300010
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.81 n.3 2009
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
instacron:ABC
instname_str Academia Brasileira de Ciências (ABC)
instacron_str ABC
institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
repository.mail.fl_str_mv ||aabc@abc.org.br
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