Red cabbage (Brassica oleracea L.) extract reverses lipid oxidative stress in rats

• Autor(a) principal: VEBER,BRUNO
• Data de Publicação: 2020
• Outros Autores: CAMARGO,ANDERSON, DALMAGRO,ANA PAULA, BONDE,HENRIQUE LUIS P., MAGRO,DÉBORA D. DAL, LIMA,DANIELA D. DE, ZENI,ANA LÚCIA B.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Anais da Academia Brasileira de Ciências (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100711
• topic: red cabbage; Brassica oleracea; oxidative stress; antioxidants; Triton WR-1339

Abstract Red cabbage (Brassica oleracea L. var. capitata f. rubra DC.) extract has been demonstrated hypolipidemic and antioxidant capacity. Herein, we investigated the effect of red cabbage aqueous extract (RC) or fenofibrate (FF) in oxidative stress induced by Triton WR-1339 in rats. The antioxidant capacity was evaluated through the superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities and, thiobarbituric reactive species (TBARS) and protein carbonyl (PC) levels in erythrocytes, liver, kidneys, cerebral cortex and hippocampus of male rats. The alterations promoted by Triton WR-1339 in enzymatic antioxidant defense in the liver, kidneys and hippocampus were reversed by RC or FF treatments. The TBARS and PC levels increased in the liver, cerebral cortex and hippocampus of hyperlipidemic rats were decreased by the treatments with RC or FF. These findings demonstrated that RC is a potential therapy to treat diseases not only involving dyslipidemic condition but also oxidative stress.