Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour

Detalhes bibliográficos
Autor(a) principal: MOREIRA,DAVYSON L.
Data de Publicação: 2001
Outros Autores: SOUZA,PATRÍCIA O., KAPLAN,MARIA AUXILIADORA C., PEREIRA,NUNO A., CARDOSO,GERALDO L., GUIMARÃES,ELSIE F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004
Resumo: The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals.
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spelling Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviourPiperaceaePiper solmsianumessential oilsarisanpsychopharmacologic effectThe essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals.Academia Brasileira de Ciências2001-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004Anais da Academia Brasileira de Ciências v.73 n.1 2001reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/S0001-37652001000100004info:eu-repo/semantics/openAccessMOREIRA,DAVYSON L.SOUZA,PATRÍCIA O.KAPLAN,MARIA AUXILIADORA C.PEREIRA,NUNO A.CARDOSO,GERALDO L.GUIMARÃES,ELSIE F.eng2001-03-08T00:00:00Zoai:scielo:S0001-37652001000100004Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2001-03-08T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
title Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
spellingShingle Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
MOREIRA,DAVYSON L.
Piperaceae
Piper solmsianum
essential oil
sarisan
psychopharmacologic effect
title_short Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
title_full Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
title_fullStr Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
title_full_unstemmed Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
title_sort Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
author MOREIRA,DAVYSON L.
author_facet MOREIRA,DAVYSON L.
SOUZA,PATRÍCIA O.
KAPLAN,MARIA AUXILIADORA C.
PEREIRA,NUNO A.
CARDOSO,GERALDO L.
GUIMARÃES,ELSIE F.
author_role author
author2 SOUZA,PATRÍCIA O.
KAPLAN,MARIA AUXILIADORA C.
PEREIRA,NUNO A.
CARDOSO,GERALDO L.
GUIMARÃES,ELSIE F.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv MOREIRA,DAVYSON L.
SOUZA,PATRÍCIA O.
KAPLAN,MARIA AUXILIADORA C.
PEREIRA,NUNO A.
CARDOSO,GERALDO L.
GUIMARÃES,ELSIE F.
dc.subject.por.fl_str_mv Piperaceae
Piper solmsianum
essential oil
sarisan
psychopharmacologic effect
topic Piperaceae
Piper solmsianum
essential oil
sarisan
psychopharmacologic effect
description The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals.
publishDate 2001
dc.date.none.fl_str_mv 2001-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0001-37652001000100004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.73 n.1 2001
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
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instname_str Academia Brasileira de Ciências (ABC)
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institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
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