Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
Autor(a) principal: | |
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Data de Publicação: | 2001 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais da Academia Brasileira de Ciências (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004 |
Resumo: | The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals. |
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Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviourPiperaceaePiper solmsianumessential oilsarisanpsychopharmacologic effectThe essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals.Academia Brasileira de Ciências2001-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004Anais da Academia Brasileira de Ciências v.73 n.1 2001reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/S0001-37652001000100004info:eu-repo/semantics/openAccessMOREIRA,DAVYSON L.SOUZA,PATRÍCIA O.KAPLAN,MARIA AUXILIADORA C.PEREIRA,NUNO A.CARDOSO,GERALDO L.GUIMARÃES,ELSIE F.eng2001-03-08T00:00:00Zoai:scielo:S0001-37652001000100004Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2001-03-08T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false |
dc.title.none.fl_str_mv |
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour |
title |
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour |
spellingShingle |
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour MOREIRA,DAVYSON L. Piperaceae Piper solmsianum essential oil sarisan psychopharmacologic effect |
title_short |
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour |
title_full |
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour |
title_fullStr |
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour |
title_full_unstemmed |
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour |
title_sort |
Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour |
author |
MOREIRA,DAVYSON L. |
author_facet |
MOREIRA,DAVYSON L. SOUZA,PATRÍCIA O. KAPLAN,MARIA AUXILIADORA C. PEREIRA,NUNO A. CARDOSO,GERALDO L. GUIMARÃES,ELSIE F. |
author_role |
author |
author2 |
SOUZA,PATRÍCIA O. KAPLAN,MARIA AUXILIADORA C. PEREIRA,NUNO A. CARDOSO,GERALDO L. GUIMARÃES,ELSIE F. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
MOREIRA,DAVYSON L. SOUZA,PATRÍCIA O. KAPLAN,MARIA AUXILIADORA C. PEREIRA,NUNO A. CARDOSO,GERALDO L. GUIMARÃES,ELSIE F. |
dc.subject.por.fl_str_mv |
Piperaceae Piper solmsianum essential oil sarisan psychopharmacologic effect |
topic |
Piperaceae Piper solmsianum essential oil sarisan psychopharmacologic effect |
description |
The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals. |
publishDate |
2001 |
dc.date.none.fl_str_mv |
2001-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0001-37652001000100004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
dc.source.none.fl_str_mv |
Anais da Academia Brasileira de Ciências v.73 n.1 2001 reponame:Anais da Academia Brasileira de Ciências (Online) instname:Academia Brasileira de Ciências (ABC) instacron:ABC |
instname_str |
Academia Brasileira de Ciências (ABC) |
instacron_str |
ABC |
institution |
ABC |
reponame_str |
Anais da Academia Brasileira de Ciências (Online) |
collection |
Anais da Academia Brasileira de Ciências (Online) |
repository.name.fl_str_mv |
Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC) |
repository.mail.fl_str_mv |
||aabc@abc.org.br |
_version_ |
1754302855450198016 |