Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering

Detalhes bibliográficos
Autor(a) principal: JAGANATHAN,SARAVANA KUMAR
Data de Publicação: 2020
Outros Autores: MANI,MOHAN P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000101101
Resumo: Abstract Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. The contact angle results revealed the decreased wettability (116° ± 1.528) of the prepared nanocomposites compared to the pure PU (100° ± 0.5774). The incorporation of amla oil into the PU matrix improved the surface roughness. Further, the coagulation assay indicated that the addition of amla oil into PU delayed the blood clotting times and exhibited less toxic to red blood cells. Hence, the fabricated nanocomposites showed enhanced physicochemical and better blood compatibility parameters which may serve as a potential candidate for bone tissue engineering.
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spelling Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineeringpolyurethaneayurveda oilelectrospun scaffoldblood compatibilitybone tissue engineeringAbstract Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. The contact angle results revealed the decreased wettability (116° ± 1.528) of the prepared nanocomposites compared to the pure PU (100° ± 0.5774). The incorporation of amla oil into the PU matrix improved the surface roughness. Further, the coagulation assay indicated that the addition of amla oil into PU delayed the blood clotting times and exhibited less toxic to red blood cells. Hence, the fabricated nanocomposites showed enhanced physicochemical and better blood compatibility parameters which may serve as a potential candidate for bone tissue engineering.Academia Brasileira de Ciências2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000101101Anais da Academia Brasileira de Ciências v.92 n.1 2020reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765202020180369info:eu-repo/semantics/openAccessJAGANATHAN,SARAVANA KUMARMANI,MOHAN P.eng2020-03-25T00:00:00Zoai:scielo:S0001-37652020000101101Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2020-03-25T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
title Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
spellingShingle Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
JAGANATHAN,SARAVANA KUMAR
polyurethane
ayurveda oil
electrospun scaffold
blood compatibility
bone tissue engineering
title_short Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
title_full Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
title_fullStr Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
title_full_unstemmed Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
title_sort Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
author JAGANATHAN,SARAVANA KUMAR
author_facet JAGANATHAN,SARAVANA KUMAR
MANI,MOHAN P.
author_role author
author2 MANI,MOHAN P.
author2_role author
dc.contributor.author.fl_str_mv JAGANATHAN,SARAVANA KUMAR
MANI,MOHAN P.
dc.subject.por.fl_str_mv polyurethane
ayurveda oil
electrospun scaffold
blood compatibility
bone tissue engineering
topic polyurethane
ayurveda oil
electrospun scaffold
blood compatibility
bone tissue engineering
description Abstract Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. The contact angle results revealed the decreased wettability (116° ± 1.528) of the prepared nanocomposites compared to the pure PU (100° ± 0.5774). The incorporation of amla oil into the PU matrix improved the surface roughness. Further, the coagulation assay indicated that the addition of amla oil into PU delayed the blood clotting times and exhibited less toxic to red blood cells. Hence, the fabricated nanocomposites showed enhanced physicochemical and better blood compatibility parameters which may serve as a potential candidate for bone tissue engineering.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000101101
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000101101
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0001-3765202020180369
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.92 n.1 2020
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
instacron:ABC
instname_str Academia Brasileira de Ciências (ABC)
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institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
repository.mail.fl_str_mv ||aabc@abc.org.br
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