Entry, dispersion and differentiation of microglia in the developing central nervous system

Detalhes bibliográficos
Autor(a) principal: NAVASCUÉS,JULIO
Data de Publicação: 2000
Outros Autores: CALVENTE,RUTH, MARÍN-TEVA,JOSÉ L., CUADROS,MIGUEL A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652000000100013
Resumo: Microglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream. Once in the nervous parenchyma, microglial cells increase in number and disperse throughout the CNS; these cells finally differentiate to become fully ramified microglial cells. In this article we review present knowledge on these phases of microglial development and the factors that probably influence them.
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spelling Entry, dispersion and differentiation of microglia in the developing central nervous systemmicrogliahematopoietic lineagemeningesmigrationproliferationMicroglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream. Once in the nervous parenchyma, microglial cells increase in number and disperse throughout the CNS; these cells finally differentiate to become fully ramified microglial cells. In this article we review present knowledge on these phases of microglial development and the factors that probably influence them.Academia Brasileira de Ciências2000-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652000000100013Anais da Academia Brasileira de Ciências v.72 n.1 2000reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/S0001-37652000000100013info:eu-repo/semantics/openAccessNAVASCUÉS,JULIOCALVENTE,RUTHMARÍN-TEVA,JOSÉ L.CUADROS,MIGUEL A.eng2000-08-07T00:00:00Zoai:scielo:S0001-37652000000100013Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2000-08-07T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Entry, dispersion and differentiation of microglia in the developing central nervous system
title Entry, dispersion and differentiation of microglia in the developing central nervous system
spellingShingle Entry, dispersion and differentiation of microglia in the developing central nervous system
NAVASCUÉS,JULIO
microglia
hematopoietic lineage
meninges
migration
proliferation
title_short Entry, dispersion and differentiation of microglia in the developing central nervous system
title_full Entry, dispersion and differentiation of microglia in the developing central nervous system
title_fullStr Entry, dispersion and differentiation of microglia in the developing central nervous system
title_full_unstemmed Entry, dispersion and differentiation of microglia in the developing central nervous system
title_sort Entry, dispersion and differentiation of microglia in the developing central nervous system
author NAVASCUÉS,JULIO
author_facet NAVASCUÉS,JULIO
CALVENTE,RUTH
MARÍN-TEVA,JOSÉ L.
CUADROS,MIGUEL A.
author_role author
author2 CALVENTE,RUTH
MARÍN-TEVA,JOSÉ L.
CUADROS,MIGUEL A.
author2_role author
author
author
dc.contributor.author.fl_str_mv NAVASCUÉS,JULIO
CALVENTE,RUTH
MARÍN-TEVA,JOSÉ L.
CUADROS,MIGUEL A.
dc.subject.por.fl_str_mv microglia
hematopoietic lineage
meninges
migration
proliferation
topic microglia
hematopoietic lineage
meninges
migration
proliferation
description Microglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream. Once in the nervous parenchyma, microglial cells increase in number and disperse throughout the CNS; these cells finally differentiate to become fully ramified microglial cells. In this article we review present knowledge on these phases of microglial development and the factors that probably influence them.
publishDate 2000
dc.date.none.fl_str_mv 2000-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652000000100013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652000000100013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0001-37652000000100013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.72 n.1 2000
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
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instname_str Academia Brasileira de Ciências (ABC)
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reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
repository.mail.fl_str_mv ||aabc@abc.org.br
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