Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?

Detalhes bibliográficos
Autor(a) principal: FISCHER,MARTA L.
Data de Publicação: 2021
Outros Autores: RODRIGUES,GABRIELA S., AGUERO,WINDY P., ZOTZ,RAFAEL, SIMÃO-SILVA,DAIANE P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000101102
Resumo: Abstract The Environmental enrichment technique, although scientifically recognized for raising the level of animal welfare, has led to the questioning of its influence on the results of experimental research. Thus, the goal is to promote reflection about the need for standardization of these procedures. For that, documents and experimental analysis were done, in order to quantify and characterize the types of environmental enrichment used and to evaluate the effect of that in the social behavior of Rattus norvegicus. Data from the document review confirmed the hypothesis that the researchers have used a variety of methods, not demonstrating a concern for standardization and prior assessment of its effects on the search results. Demand was corroborated in the experimental study in which, although there was available a simple object acting as refuge promotes behavioral improvements, the presence of the co-specific, as well as characteristics of the micro and macro environment can compromise the homogeneity of the sample. The data from this study endorse the need for validation procedures of environmental enrichment for specific proposals, to investigative data comparison, are possible and contribute to the refinement of the search to reduce the number of animals targeted for this purpose.
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spelling Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?animal ethicsanimal modelanimal experimentationanimal welfare principle of 3R’sRattus norvegicusAbstract The Environmental enrichment technique, although scientifically recognized for raising the level of animal welfare, has led to the questioning of its influence on the results of experimental research. Thus, the goal is to promote reflection about the need for standardization of these procedures. For that, documents and experimental analysis were done, in order to quantify and characterize the types of environmental enrichment used and to evaluate the effect of that in the social behavior of Rattus norvegicus. Data from the document review confirmed the hypothesis that the researchers have used a variety of methods, not demonstrating a concern for standardization and prior assessment of its effects on the search results. Demand was corroborated in the experimental study in which, although there was available a simple object acting as refuge promotes behavioral improvements, the presence of the co-specific, as well as characteristics of the micro and macro environment can compromise the homogeneity of the sample. The data from this study endorse the need for validation procedures of environmental enrichment for specific proposals, to investigative data comparison, are possible and contribute to the refinement of the search to reduce the number of animals targeted for this purpose.Academia Brasileira de Ciências2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000101102Anais da Academia Brasileira de Ciências v.93 n.1 2021reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765202120191526info:eu-repo/semantics/openAccessFISCHER,MARTA L.RODRIGUES,GABRIELA S.AGUERO,WINDY P.ZOTZ,RAFAELSIMÃO-SILVA,DAIANE P.eng2021-03-22T00:00:00Zoai:scielo:S0001-37652021000101102Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2021-03-22T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
title Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
spellingShingle Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
FISCHER,MARTA L.
animal ethics
animal model
animal experimentation
animal welfare principle of 3R’s
Rattus norvegicus
title_short Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
title_full Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
title_fullStr Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
title_full_unstemmed Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
title_sort Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
author FISCHER,MARTA L.
author_facet FISCHER,MARTA L.
RODRIGUES,GABRIELA S.
AGUERO,WINDY P.
ZOTZ,RAFAEL
SIMÃO-SILVA,DAIANE P.
author_role author
author2 RODRIGUES,GABRIELA S.
AGUERO,WINDY P.
ZOTZ,RAFAEL
SIMÃO-SILVA,DAIANE P.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv FISCHER,MARTA L.
RODRIGUES,GABRIELA S.
AGUERO,WINDY P.
ZOTZ,RAFAEL
SIMÃO-SILVA,DAIANE P.
dc.subject.por.fl_str_mv animal ethics
animal model
animal experimentation
animal welfare principle of 3R’s
Rattus norvegicus
topic animal ethics
animal model
animal experimentation
animal welfare principle of 3R’s
Rattus norvegicus
description Abstract The Environmental enrichment technique, although scientifically recognized for raising the level of animal welfare, has led to the questioning of its influence on the results of experimental research. Thus, the goal is to promote reflection about the need for standardization of these procedures. For that, documents and experimental analysis were done, in order to quantify and characterize the types of environmental enrichment used and to evaluate the effect of that in the social behavior of Rattus norvegicus. Data from the document review confirmed the hypothesis that the researchers have used a variety of methods, not demonstrating a concern for standardization and prior assessment of its effects on the search results. Demand was corroborated in the experimental study in which, although there was available a simple object acting as refuge promotes behavioral improvements, the presence of the co-specific, as well as characteristics of the micro and macro environment can compromise the homogeneity of the sample. The data from this study endorse the need for validation procedures of environmental enrichment for specific proposals, to investigative data comparison, are possible and contribute to the refinement of the search to reduce the number of animals targeted for this purpose.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000101102
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000101102
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0001-3765202120191526
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.93 n.1 2021
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
instacron:ABC
instname_str Academia Brasileira de Ciências (ABC)
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institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
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