The use of non-human primates as animal models for the study of hepatitis viruses

Detalhes bibliográficos
Autor(a) principal: Vitral,C.L.
Data de Publicação: 1998
Outros Autores: Yoshida,C.F.T., Gaspar,A.M.C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Medical and Biological Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000800003
Resumo: Hepatitis viruses belong to different families and have in common a striking hepatotropism and restrictions for propagation in cell culture. The transmissibility of hepatitis is in great part limited to non-human primates. Enterically transmitted hepatitis viruses (hepatitis A virus and hepatitis E virus) can induce hepatitis in a number of Old World and New World monkey species, while the host range of non-human primates susceptible to hepatitis viruses transmitted by the parenteral route (hepatitis B virus, hepatitis C virus and hepatitis delta virus) is restricted to few species of Old World monkeys, especially the chimpanzee. Experimental studies on non-human primates have provided an invaluable source of information regarding the biology and pathogenesis of these viruses, and represent a still indispensable tool for vaccine and drug testing.
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spelling The use of non-human primates as animal models for the study of hepatitis viruseshepatitis virusesnon-human primatesanimal modelexperimental infectionHepatitis viruses belong to different families and have in common a striking hepatotropism and restrictions for propagation in cell culture. The transmissibility of hepatitis is in great part limited to non-human primates. Enterically transmitted hepatitis viruses (hepatitis A virus and hepatitis E virus) can induce hepatitis in a number of Old World and New World monkey species, while the host range of non-human primates susceptible to hepatitis viruses transmitted by the parenteral route (hepatitis B virus, hepatitis C virus and hepatitis delta virus) is restricted to few species of Old World monkeys, especially the chimpanzee. Experimental studies on non-human primates have provided an invaluable source of information regarding the biology and pathogenesis of these viruses, and represent a still indispensable tool for vaccine and drug testing.Associação Brasileira de Divulgação Científica1998-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000800003Brazilian Journal of Medical and Biological Research v.31 n.8 1998reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X1998000800003info:eu-repo/semantics/openAccessVitral,C.L.Yoshida,C.F.T.Gaspar,A.M.C.eng1998-09-21T00:00:00Zoai:scielo:S0100-879X1998000800003Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:1998-09-21T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false
dc.title.none.fl_str_mv The use of non-human primates as animal models for the study of hepatitis viruses
title The use of non-human primates as animal models for the study of hepatitis viruses
spellingShingle The use of non-human primates as animal models for the study of hepatitis viruses
Vitral,C.L.
hepatitis viruses
non-human primates
animal model
experimental infection
title_short The use of non-human primates as animal models for the study of hepatitis viruses
title_full The use of non-human primates as animal models for the study of hepatitis viruses
title_fullStr The use of non-human primates as animal models for the study of hepatitis viruses
title_full_unstemmed The use of non-human primates as animal models for the study of hepatitis viruses
title_sort The use of non-human primates as animal models for the study of hepatitis viruses
author Vitral,C.L.
author_facet Vitral,C.L.
Yoshida,C.F.T.
Gaspar,A.M.C.
author_role author
author2 Yoshida,C.F.T.
Gaspar,A.M.C.
author2_role author
author
dc.contributor.author.fl_str_mv Vitral,C.L.
Yoshida,C.F.T.
Gaspar,A.M.C.
dc.subject.por.fl_str_mv hepatitis viruses
non-human primates
animal model
experimental infection
topic hepatitis viruses
non-human primates
animal model
experimental infection
description Hepatitis viruses belong to different families and have in common a striking hepatotropism and restrictions for propagation in cell culture. The transmissibility of hepatitis is in great part limited to non-human primates. Enterically transmitted hepatitis viruses (hepatitis A virus and hepatitis E virus) can induce hepatitis in a number of Old World and New World monkey species, while the host range of non-human primates susceptible to hepatitis viruses transmitted by the parenteral route (hepatitis B virus, hepatitis C virus and hepatitis delta virus) is restricted to few species of Old World monkeys, especially the chimpanzee. Experimental studies on non-human primates have provided an invaluable source of information regarding the biology and pathogenesis of these viruses, and represent a still indispensable tool for vaccine and drug testing.
publishDate 1998
dc.date.none.fl_str_mv 1998-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000800003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000800003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-879X1998000800003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv Brazilian Journal of Medical and Biological Research v.31 n.8 1998
reponame:Brazilian Journal of Medical and Biological Research
instname:Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
instname_str Associação Brasileira de Divulgação Científica (ABDC)
instacron_str ABDC
institution ABDC
reponame_str Brazilian Journal of Medical and Biological Research
collection Brazilian Journal of Medical and Biological Research
repository.name.fl_str_mv Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)
repository.mail.fl_str_mv bjournal@terra.com.br||bjournal@terra.com.br
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