A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences

Detalhes bibliográficos
Autor(a) principal: Mello-Coelho,V. de
Data de Publicação: 2005
Outros Autores: Hess,K.L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Medical and Biological Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000011
Resumo: cDNA microarray is an innovative technology that facilitates the analysis of the expression of thousands of genes simultaneously. The utilization of this methodology, which is rapidly evolving, requires a combination of expertise from the biological, mathematical and statistical sciences. In this review, we attempt to provide an overview of the principles of cDNA microarray technology, the practical concerns of the analytical processing of the data obtained, the correlation of this methodology with other data analysis methods such as immunohistochemistry in tissue microarrays, and the cDNA microarray application in distinct areas of the basic and clinical sciences.
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spelling A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciencesBiotechnologycDNA microarrayGene expressionGenomicscDNA microarray is an innovative technology that facilitates the analysis of the expression of thousands of genes simultaneously. The utilization of this methodology, which is rapidly evolving, requires a combination of expertise from the biological, mathematical and statistical sciences. In this review, we attempt to provide an overview of the principles of cDNA microarray technology, the practical concerns of the analytical processing of the data obtained, the correlation of this methodology with other data analysis methods such as immunohistochemistry in tissue microarrays, and the cDNA microarray application in distinct areas of the basic and clinical sciences.Associação Brasileira de Divulgação Científica2005-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000011Brazilian Journal of Medical and Biological Research v.38 n.10 2005reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2005001000011info:eu-repo/semantics/openAccessMello-Coelho,V. deHess,K.L.eng2005-11-01T00:00:00Zoai:scielo:S0100-879X2005001000011Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2005-11-01T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false
dc.title.none.fl_str_mv A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences
title A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences
spellingShingle A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences
Mello-Coelho,V. de
Biotechnology
cDNA microarray
Gene expression
Genomics
title_short A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences
title_full A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences
title_fullStr A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences
title_full_unstemmed A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences
title_sort A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences
author Mello-Coelho,V. de
author_facet Mello-Coelho,V. de
Hess,K.L.
author_role author
author2 Hess,K.L.
author2_role author
dc.contributor.author.fl_str_mv Mello-Coelho,V. de
Hess,K.L.
dc.subject.por.fl_str_mv Biotechnology
cDNA microarray
Gene expression
Genomics
topic Biotechnology
cDNA microarray
Gene expression
Genomics
description cDNA microarray is an innovative technology that facilitates the analysis of the expression of thousands of genes simultaneously. The utilization of this methodology, which is rapidly evolving, requires a combination of expertise from the biological, mathematical and statistical sciences. In this review, we attempt to provide an overview of the principles of cDNA microarray technology, the practical concerns of the analytical processing of the data obtained, the correlation of this methodology with other data analysis methods such as immunohistochemistry in tissue microarrays, and the cDNA microarray application in distinct areas of the basic and clinical sciences.
publishDate 2005
dc.date.none.fl_str_mv 2005-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-879X2005001000011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv Brazilian Journal of Medical and Biological Research v.38 n.10 2005
reponame:Brazilian Journal of Medical and Biological Research
instname:Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
instname_str Associação Brasileira de Divulgação Científica (ABDC)
instacron_str ABDC
institution ABDC
reponame_str Brazilian Journal of Medical and Biological Research
collection Brazilian Journal of Medical and Biological Research
repository.name.fl_str_mv Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)
repository.mail.fl_str_mv bjournal@terra.com.br||bjournal@terra.com.br
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