Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
Autor(a) principal: | |
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Data de Publicação: | 2004 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Medical and Biological Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300015 |
Resumo: | More than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms. |
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Brazilian Journal of Medical and Biological Research |
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Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic ForestPlant extractAntibacterial activityScreeningAmazon Rain ForestAtlantic ForestMore than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms.Associação Brasileira de Divulgação Científica2004-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300015Brazilian Journal of Medical and Biological Research v.37 n.3 2004reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2004000300015info:eu-repo/semantics/openAccessSuffredini,I.B.Sader,H.S.Gonçalves,A.G.Reis,A.O.Gales,A.C.Varella,A.D.Younes,R.N.eng2004-04-20T00:00:00Zoai:scielo:S0100-879X2004000300015Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2004-04-20T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false |
dc.title.none.fl_str_mv |
Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest |
title |
Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest |
spellingShingle |
Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest Suffredini,I.B. Plant extract Antibacterial activity Screening Amazon Rain Forest Atlantic Forest |
title_short |
Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest |
title_full |
Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest |
title_fullStr |
Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest |
title_full_unstemmed |
Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest |
title_sort |
Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest |
author |
Suffredini,I.B. |
author_facet |
Suffredini,I.B. Sader,H.S. Gonçalves,A.G. Reis,A.O. Gales,A.C. Varella,A.D. Younes,R.N. |
author_role |
author |
author2 |
Sader,H.S. Gonçalves,A.G. Reis,A.O. Gales,A.C. Varella,A.D. Younes,R.N. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Suffredini,I.B. Sader,H.S. Gonçalves,A.G. Reis,A.O. Gales,A.C. Varella,A.D. Younes,R.N. |
dc.subject.por.fl_str_mv |
Plant extract Antibacterial activity Screening Amazon Rain Forest Atlantic Forest |
topic |
Plant extract Antibacterial activity Screening Amazon Rain Forest Atlantic Forest |
description |
More than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms. |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300015 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-879X2004000300015 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research v.37 n.3 2004 reponame:Brazilian Journal of Medical and Biological Research instname:Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC |
instname_str |
Associação Brasileira de Divulgação Científica (ABDC) |
instacron_str |
ABDC |
institution |
ABDC |
reponame_str |
Brazilian Journal of Medical and Biological Research |
collection |
Brazilian Journal of Medical and Biological Research |
repository.name.fl_str_mv |
Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC) |
repository.mail.fl_str_mv |
bjournal@terra.com.br||bjournal@terra.com.br |
_version_ |
1754302932948353024 |