Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest

Detalhes bibliográficos
Autor(a) principal: Suffredini,I.B.
Data de Publicação: 2004
Outros Autores: Sader,H.S., Gonçalves,A.G., Reis,A.O., Gales,A.C., Varella,A.D., Younes,R.N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Medical and Biological Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300015
Resumo: More than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms.
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spelling Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic ForestPlant extractAntibacterial activityScreeningAmazon Rain ForestAtlantic ForestMore than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms.Associação Brasileira de Divulgação Científica2004-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300015Brazilian Journal of Medical and Biological Research v.37 n.3 2004reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2004000300015info:eu-repo/semantics/openAccessSuffredini,I.B.Sader,H.S.Gonçalves,A.G.Reis,A.O.Gales,A.C.Varella,A.D.Younes,R.N.eng2004-04-20T00:00:00Zoai:scielo:S0100-879X2004000300015Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2004-04-20T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false
dc.title.none.fl_str_mv Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
spellingShingle Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
Suffredini,I.B.
Plant extract
Antibacterial activity
Screening
Amazon Rain Forest
Atlantic Forest
title_short Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title_full Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title_fullStr Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title_full_unstemmed Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
title_sort Screening of antibacterial extracts from plants native to the Brazilian Amazon Rain Forest and Atlantic Forest
author Suffredini,I.B.
author_facet Suffredini,I.B.
Sader,H.S.
Gonçalves,A.G.
Reis,A.O.
Gales,A.C.
Varella,A.D.
Younes,R.N.
author_role author
author2 Sader,H.S.
Gonçalves,A.G.
Reis,A.O.
Gales,A.C.
Varella,A.D.
Younes,R.N.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Suffredini,I.B.
Sader,H.S.
Gonçalves,A.G.
Reis,A.O.
Gales,A.C.
Varella,A.D.
Younes,R.N.
dc.subject.por.fl_str_mv Plant extract
Antibacterial activity
Screening
Amazon Rain Forest
Atlantic Forest
topic Plant extract
Antibacterial activity
Screening
Amazon Rain Forest
Atlantic Forest
description More than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 µg/ml, using a microdilution broth assay against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and Escherichia coli. One extract, VO581, was active against S. aureus (minimum inhibitory concentration (MIC) = 140 µg/ml and minimal bactericidal concentration (MBC) = 160 µg/ml, organic extract obtained from stems) and two extracts were active against E. faecalis, SM053 (MIC = 80 µg/ml and MBC = 90 µg/ml, organic extract obtained from aerial parts), and MY841 (MIC = 30 µg/ml and MBC = 50 µg/ml, organic extract obtained from stems). The most active fractions are being fractionated to identify their active substances. Higher concentrations of other extracts are currently being evaluated against the same microorganisms.
publishDate 2004
dc.date.none.fl_str_mv 2004-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-879X2004000300015
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv Brazilian Journal of Medical and Biological Research v.37 n.3 2004
reponame:Brazilian Journal of Medical and Biological Research
instname:Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
instname_str Associação Brasileira de Divulgação Científica (ABDC)
instacron_str ABDC
institution ABDC
reponame_str Brazilian Journal of Medical and Biological Research
collection Brazilian Journal of Medical and Biological Research
repository.name.fl_str_mv Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)
repository.mail.fl_str_mv bjournal@terra.com.br||bjournal@terra.com.br
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